Tolnip Plus 150mg/325mg Tablet belongs to the class of medicine called 'muscle relaxant' in combination with a painkiller, used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

Tolnip Plus 150mg/325mg Tablet is a combination of two drugs: Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Tolnip Plus 150mg/325mg Tablet include nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. These side effects are not familiar to everyone and vary individually.

Let your doctor know if you use any prescription and non-prescription medications before starting Tolnip Plus 150mg/325mg Tablet. Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking Tolnip Plus 150mg/325mg Tablet if you are pregnant or planning for pregnancy. Tolnip Plus 150mg/325mg Tablet may cause dizziness, so drive only if you are alert and focused. Tolnip Plus 150mg/325mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol and Tolnip Plus 150mg/325mg Tablet as it could lead to increased dizziness and risk of liver damage.

Tolnip Plus 150mg/325mg Tablet treats muscle spasms and consists of Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting Tolnip Plus 150mg/325mg Tablet. Consult your doctor before taking Tolnip Plus 150mg/325mg Tablet if you are pregnant, planning for pregnancy or breastfeeding. Tolnip Plus 150mg/325mg Tablet may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Tolnip Plus 150mg/325mg Tablet as it could lead to increased dizziness and risk of liver damage. Tolnip Plus 150mg/325mg Tablet is not recommended in children as safety and efficacy is not established.

• Let your doctor know that you are taking Tolnip Plus 150mg/325mg Tablet if you are undergoing any medical tests.
• Tolnip Plus 150mg/325mg Tablet may cause fluid retention (oedema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
• Explain a detail history to the doctor as use of Tolnip Plus 150mg/325mg Tablet is contraindicated in patients with myasthenia gravis.