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  3. TORISEL 25MG INJECTION

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

TEMSIROLIMUS-25MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Other Info - TOR0218

FAQs

TORISEL 25MG INJECTION works by blocking tumour cell growth and division. Thereby, it helps treat kidney cancer.

TORISEL 25MG INJECTION may result in immunosuppression, leading to an increased risk of infections. Wash your hands frequently and avoid contact with sick people.

Vaccination may be less effective if taken during treatment with TORISEL 25MG INJECTION. Also, some vaccinations should be avoided during treatment. Therefore, do not have any vaccinations without consulting the doctor.

Fertility may be compromised during treatment with TORISEL 25MG INJECTION. Consult the doctor if you have any concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with TORISEL 25MG INJECTION. Please consult the doctor.

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Pregnancy

Caution

TORISEL 25MG INJECTION may cause fetal harm when administered to pregnant women. TORISEL 25MG INJECTION should not be used during pregnancy unless clearly necessary. Consult the doctor if you are pregnant, planning for pregnancy, or thinking you may be pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while using TORISEL 25MG INJECTION and for three weeks after the last dose.

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Driving

Not applicable

TORISEL 25MG INJECTION is unlikely to affect your ability to drive.

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Liver

Caution

TORISEL 25MG INJECTION is not recommended in patients with liver problems. Consult the doctor if you have/had liver problems.

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Kidney

Caution

Please consult the doctor if you have kidney impairment or any concerns regarding this. Your doctor may monitor kidney function while on treatment with this medicine.

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Children

Unsafe

TORISEL 25MG INJECTION is not recommended for children below 18 years as effectiveness has not been established.

About TORISEL 25MG INJECTION

TORISEL 25MG INJECTION belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes).
 
TORISEL 25MG INJECTION contains Temsirolimus, which works by blocking the action of abnormal proteins needed for cancer cells to multiply. This helps slow the growth of tumours. Thereby, it helps treat kidney cancer.
 
In some cases, TORISEL 25MG INJECTION may cause side effects such as diarrhoea, nausea, vomiting, constipation, headache, fever, and decreased appetite. Most of these side effects may not require medical attention and resolve over time. Do not be reluctant to talk with your doctor if any of these side effects persist or worsen.
 
Consult the doctor if you are pregnant or breastfeeding. TORISEL 25MG INJECTION is not recommended for children below 18 years as the effectiveness has not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of TORISEL 25MG INJECTION

 Renal cell cancer (Kidney cancer).

Medicinal Benefits Mweb

Medicinal Benefits

TORISEL 25MG INJECTION belongs to the group of anti-cancer medicines called kinase inhibitors used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidney). It may also be used for previously treated mantle cell lymphoma (a type of cancer affecting the lymph nodes). TORISEL 25MG INJECTION contains Temsirolimus, a selective inhibitor of the enzyme mTOR (mammalian target of rapamycin) that blocks tumour cell growth and division. Thereby, it helps treat kidney cancer.

Directions for Use

TORISEL 25MG INJECTION will be administered by a healthcare professional who is trained and experienced in the administration of anticancer medicine; do not self-administer.

Side Effects of TORISEL 25MG INJECTION

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Fever
  • Loss of appetite
  • Sores or inflammation in the mouth
  • Cough

Drug Warnings

Do not use TORISEL 25MG INJECTION if you are allergic to any of its components if you are allergic to sirolimus (immunosuppressant), or if you have mantle cell lymphoma or liver problems. Inform the doctor if you are allergic to or cannot use anti-histamines if you have/had a tumour in the brain or spinal cord, bruising/bleeding problems, infections, inflammation of lungs, liver or kidney problems, high cholesterol levels, diabetes, eye problems, if you are taking anticoagulants if you drink alcohol or are alcoholic if you are due to undergo any vaccination or surgery, or if you are over 65 years of age. Consult the doctor if you are pregnant or breastfeeding. TORISEL 25MG INJECTION is not recommended for children below 18 years as the effectiveness has not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Torisel 25mg Injection:
Taking Etodolac and Torisel 25mg Injection can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Etodolac and Torisel 25mg Injection, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Torisel 25mg Injection:
Taking Piroxicam with Torisel 25mg Injection may increase the risk of kidney damage.

How to manage the interaction:
Taking Piroxicam with Torisel 25mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Torisel 25mg Injection:
Coadministration of Amphotericin b and Torisel 25mg Injection may increase the risk of kidney problem.

How to manage the interaction:
Although taking Amphotericin b and Torisel 25mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any changes like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Torisel 25mg Injection:
Taking Torisel 25mg Injection and Ezetimibe can increase blood levels of cholesterol and triglycerides.

How to manage the interaction:
There may be a possibility of interaction between Ezetimibe and Torisel 25mg Injection, but it can be taken if prescribed by a doctor. If you are taking sirolimus or Torisel 25mg Injection along with your cholesterol-lowering medications, it is important to regularly check blood cholesterol and triglyceride levels with a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Torisel 25mg Injection:
When Torisel 25mg Injection is taken with Infliximab, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Infliximab and Torisel 25mg Injection, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Torisel 25mg Injection:
Co-administration of Gentamicin and Torisel 25mg Injection may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Gentamicin with Torisel 25mg Injection can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
How does the drug interact with Torisel 25mg Injection:
Coadministration of Vancomycin with Torisel 25mg Injection can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Torisel 25mg Injection may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
TemsirolimusFosphenytoin
Severe
How does the drug interact with Torisel 25mg Injection:
When Torisel 25mg Injection is taken with Fosphenytoin, it can cause Torisel 25mg Injection to be broken down faster in the body. This can lead to low treatment outcomes

How to manage the interaction:
Although taking Fosphenytoin and Torisel 25mg Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any unusual symptoms or if your condition worsens, make sure to contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Torisel 25mg Injection:
Taking fondaparinux with Torisel 25mg Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Fondaparinux with Torisel 25mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Torisel 25mg Injection:
Coadministration of Naproxen and Torisel 25mg Injection may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Naproxen and Torisel 25mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • NEFAZODONE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFABUTIN
  • ST JOHN'S WORT
  • ENALAPRIL
  • RAMIPRIL
  • LISINOPRIL
  • AMLODIPINE
  • AMIODARONE
  • SUNITINIB

Habit Forming

No

Special Advise

Females of reproductive potential and males with partners of reproductive potential must use effective contraception during treatment and for three months after the last dose.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, whole grains and fruits in your diet.
  • Avoid fast, fried foods, processed meats, highly processed foods and beverages, and salty snacks.
  • Get optimal sleep; rest well.

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