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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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Whats That

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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- TUBERCULOSIS

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - TRA0117

Author Details

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FAQs

Trac-4 Tablet is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide, and ethambutol. Trac-4 Tablet works by killing the bacteria named Mycobacterium tuberculosis which causes TB (tuberculosis).

Do not stop taking Trac-4 Tablet despite symptomatic relief. To treat your condition effectually, continue taking Trac-4 Tablet for as long as it has been prescribed for you.

Do not take Trac-4 Tablet along with antacids as it might decrease the effectiveness of Trac-4 Tablet. Maintain a minimum gap of 1 hour between both. However, please consult your doctor before taking other medicines with Trac-4 Tablet.

Consult your doctor before taking Trac-4 Tablet with other medicines. Your doctor would suggest the right time, dose and precautions before taking Trac-4 Tablet with other drugs.

Trac-4 Tablet contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer. Avoid these foods while taking Trac-4 Tablet.

Trac-4 Tablet might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking Trac-4 Tablet. Consult your doctor if you have any concerns regarding this, your doctor may suggest an alternate method of contraception.

Trac-4 Tablet may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva or tears. The colour in tears may last for some time even after you stop taking Trac-4 Tablet. Do not worry as it is a common side-effect of Trac-4 Tablet.

Yes, Trac-4 Tablet might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking Trac-4 Tablet.

Trac-4 Tablet may affect test results of some blood tests such as tests for folate, vitamin B12 and liver function. Inform the person doing the tests that you are taking Trac-4 Tablet.

Yes, Trac-4 Tablet may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking Trac-4 Tablet to check how your liver is functioning.

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Alcohol

Unsafe

Avoid alcohol consumption while taking Trac-4 Tablet as it could lead to increased dizziness and liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe Trac-4 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Trac-4 Tablet passes into breast milk. Do not breastfeed while taking Trac-4 Tablet. Consult your doctor for further advice.

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Driving

Unsafe

Trac-4 Tablet may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Trac-4 Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

Trac-4 Tablet is not recommended for use in children.

About Trac-4 Tablet

Trac-4 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. Trac-4 Tablet does not work against infections caused by the virus, including cold and flu.

Trac-4 Tablet is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and to reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.

The dose and duration of Trac-4 Tablet can vary depending upon your condition and severity of the infection. In some cases, you may experience certain common side-effects such as weakness, nausea, vomiting, malaise (feeling of discomfort), fatigue and vision problems. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer while taking Trac-4 Tablet as they might cause interaction. Maintain a gap of one hour between Trac-4 Tablet and antacid medicines. Consult your doctor before taking Trac-4 Tablet if you are pregnant. Avoid breastfeeding while taking Trac-4 Tablet as it passes into breast milk. Trac-4 Tablet is not recommended for use in children. Trac-4 Tablet may cause dizziness and vision problems, so drive only if you are alert. Avoid consuming alcohol along with Trac-4 Tablet as it might lead to liver problems and increased dizziness.

Uses of Trac-4 Tablet

Tuberculosis (TB)

Medicinal Benefits Mweb

Medicinal Benefits

Trac-4 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Trac-4 Tablet is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide and ethambutol. Isoniazid prevents the formation of the bacterial cell wall, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria (Mycobacterium tuberculosis) to make essential proteins and to reproduce. Ethambutol and pyrazinamide work by slowing the growth of bacteria. Altogether, they kill the bacteria and treat the infection.

Directions for Use

Take Trac-4 Tablet 30 minutes before food or 2 hours after food. Swallow Trac-4 Tablet as a whole with water, do not crush or chew it.

Side Effects of Trac-4 Tablet

  • Weakness
  • Nausea
  • Vomiting
  • Malaise (feeling of discomfort)
  • Fatigue
  • Vision problems

Drug Warnings

Do not take Trac-4 Tablet if you are allergic to any of its contents, if you have jaundice or if you are taking HIV medicines (saquinavir or ritonavir). Before starting Trac-4 Tablet, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking Trac-4 Tablet if you are pregnant. Avoid breastfeeding while taking Trac-4 Tablet as it passes into breast milk. Trac-4 Tablet is not recommended for use in children. Trac-4 Tablet may cause dizziness and vision problems, so drive with caution. Avoid consuming alcohol along with Trac-4 Tablet as it might lead to liver problems and increased dizziness.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • ACETAMINOPHEN
  • INSULIN ISOPHANE
  • SAQUINAVIR
  • RITONAVIR
  • ISOCARBOXAZID
  • LINEZOLID
  • MOCLOBEMIDE
  • METHYLENE BLUE
  • PHENELZINE
  • PROCARBAZINE
  • RASAGILINE
  • SAFINAMIDE
  • SELEGILINE
  • TRANYLCYPROMINE
  • DILTIAZEM
  • VERAPAMIL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • ATAZANAVIR
  • WARFARIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • CICLOSPORIN
  • SIROLIMUS
  • TACROLIMUS
  • LEFLUNOMIDE
  • AZATHIOPRINE

Habit Forming

No

Special Advise

  • Trac-4 Tablet may affect test results of some blood tests such as tests for folate, vitamin B12 and liver function. Inform the person doing the tests that you are taking Trac-4 Tablet.
  • Your doctor may advise you to get regular liver tests while taking Trac-4 Tablet to check how your liver is functioning.
  • Trac-4 Tablet may cause vit B6 deficiency, your doctor may suggest vit B6 supplements while using Trac-4 Tablet.
  • Maintain a gap of one hour between Trac-4 Tablet and antacid medicines.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C such as kiwi, broccoli and bell pepper helps in improving the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
  • Quit smoking and avoid alcohol consumption.

Trac-4 Tablet Substitute

Substitutes safety advice

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