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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Trimark Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

INDIA

Manufacturer/Marketer address

Plot No: 260, H.No:1-257/260, 2nd Floor, Srinivasa Nagar, A.S.Rao Nagar, Kapra, Hyderabad-500062, Telangana, India.
Other Info - TRI1408

FAQs

Tripcobal Tablet is a combination of two drugs: Amitriptyline (antiepileptic) and Methylcobalamin (vitamin B12). Amitriptyline improves nerve signal conduction of damaged nerves. Methylcobalamin is a form of Vitamin B12 that helps in the regeneration of damaged nerves and helps produce the myelin sheath (outer protecting layer of nerves). Thus, Tripcobal Tablet promotes the healing of damaged nerves and improves nerve conduction in diabetes or traumatic conditions.

Dry mouth could be a side-effect of Tripcobal Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Tripcobal Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Tripcobal Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.

Do not discontinue Tripcobal Tablet without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Tripcobal Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Tripcobal Tablet ; your doctor will reduce the dose gradually.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Tripcobal Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Tripcobal Tablet ; your doctor will decide whether Tripcobal Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Tripcobal Tablet causes drowsiness, sleepiness, and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Tripcobal Tablet should not be given to children as the safety and efficacy have not been established.

About Tripcobal Tablet

Tripcobal Tablet belongs to a group of medications known as 'anticonvulsants' used to manage neuropathic pain due to damaged nerves. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, with a prickling, stabbing, tingling, or burning sensation. 

Tripcobal Tablet is a suspended-release tablet that combines two drugs: Mecobalamin (vitamin B12) and Amitriptyline (anticonvulsant). Mecobalamin (also known as methylcobalamin) is a form of Vitamin B12 required by the brain and nerves for producing red blood cells. Amitriptyline works by changing how nerves send messages to your brain. Together, Tripcobal Tablet helps to treat neuropathic pain (pain due to nerve damage). 

Take Tripcobal Tablet as prescribed by your doctor. Depending on your medical condition, you are advised to take Tripcobal Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Tripcobal Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Tripcobal Tablet causes drowsiness and dizziness, so drive only if you are alert. Tripcobal Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Tripcobal Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, and diabetes before using the Tripcobal Tablet . 

Uses of Tripcobal Tablet

Neuropathic pain

Medicinal Benefits Mweb

Medicinal Benefits

Tripcobal Tablet is a combination of two drugs: Methylcobalamin and Amitriptyline. Methylcobalamin is used to restore vitamin B12 in the body to treat damaged nerve conditions due to diabetes or other traumatic situations. It also has a neuroprotective activity that helps the nerve cells to function properly and treat neuropathic pain. On the other side, Amitriptyline prevents neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma or epilepsy. Together, Tripcobal Tablet helps to treat neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Tripcobal Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Heartburn
  • Dryness in mouth
  • Dizziness
  • Blurred vision

Drug Warnings

Do not take Tripcobal Tablet if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking other antidepressants like isocarboxazid, phenelzine, selegiline, tranylcypromine or have taken them in the last 14 days, have severe liver disease or if you have taken moclobemide (used to treat depression and social anxiety). Inform your doctor before taking Tripcobal Tablet if you have heart rhythm problems or hypotension. Consult your doctor immediately if you have suicidal thoughts like killing or harming yourself. Do not take Tripcobal Tablet if you are pregnant or breastfeeding unless prescribed. Tripcobal Tablet causes drowsiness and dizziness, do not drive unless you are alert. Tripcobal Tablet can be given to children above six years if prescribed by the doctor for treating bedwetting. Tripcobal Tablet should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol with Tripcobal Tablet as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Tripcobal Tablet causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug-Drug Interactions

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AmitriptylineLinezolid
Critical
AmitriptylineTranylcypromine
Critical

Drug-Drug Interactions

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AmitriptylineLinezolid
Critical
How does the drug interact with Tripcobal Tablet:
Taking Linezolid with Tripcobal Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linezolid and Tripcobal Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Tripcobal Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineTranylcypromine
Critical
How does the drug interact with Tripcobal Tablet:
Taking Tranylcypromine with Tripcobal Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although using Tranylcypromine and Tripcobal Tablet together is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
AmitriptylineFurazolidone
Critical
How does the drug interact with Tripcobal Tablet:
Combining Furazolidone with Tripcobal Tablet can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Tripcobal Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Tripcobal Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineRasagiline
Critical
How does the drug interact with Tripcobal Tablet:
Using Tripcobal Tablet together with Rasagiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Rasagiline and Tripcobal Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Inform a doctor if you have recently taken Tripcobal Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineHalofantrine
Critical
How does the drug interact with Tripcobal Tablet:
Combining Tripcobal Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Tripcobal Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Tripcobal Tablet:
Tripcobal Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Tripcobal Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineMethylene blue
Critical
How does the drug interact with Tripcobal Tablet:
Combining Methylene blue with Tripcobal Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Methylene blue and Tripcobal Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Tripcobal Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylinePimozide
Critical
How does the drug interact with Tripcobal Tablet:
Combining Tripcobal Tablet and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Tripcobal Tablet with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineBepridil
Critical
How does the drug interact with Tripcobal Tablet:
Combining Tripcobal Tablet and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Tripcobal Tablet with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylinePotassium chloride
Critical
How does the drug interact with Tripcobal Tablet:
The combination of Tripcobal Tablet and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Tripcobal Tablet and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TRAMADOL
  • TRAZODONE
  • HYDROCODONE
  • OXYCODONE
  • ACETAMINOPHEN
  • BUPROPION
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • ZOLPIDEM
  • CYCLOBENZAPRINE
  • GABAPENTIN
  • LAMOTRIGINE
  • ESCITALOPRAM
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE

Habit Forming

No

Special Advise

  •  Tripcobal Tablet can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
  • Tripcobal Tablet can cause dry mouth, so in that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Diet & Lifestyle Advise

  •  
  • Include food rich in vitamins B and D in your diet.
  • Include cayenne pepper in your diet to help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.
  •  
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