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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- HYPERTENSIVES

Country of origin

India

Manufacturer/Marketer address

Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
Other Info - TRI1450

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Triplixam 4mg/1.25mg/5mg Tablet contains Indapamide, Amlodipine, and Perindopril erbumine. Indapamide lowers blood pressure by increasing the amount of urine produced by the kidneys. Amlodipine relaxes the blood vessels, thereby improves blood flow. Perindopril erbumine widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Triplixam 4mg/1.25mg/5mg Tablet helps treat high blood pressure.

Triplixam 4mg/1.25mg/5mg Tablet may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Triplixam 4mg/1.25mg/5mg Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Do not stop taking Triplixam 4mg/1.25mg/5mg Tablet without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Triplixam 4mg/1.25mg/5mg Tablet for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Triplixam 4mg/1.25mg/5mg Tablet .

Light-headedness could be a side-effect of Triplixam 4mg/1.25mg/5mg Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Triplixam 4mg/1.25mg/5mg Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Avoid consuming grapefruit and grapefruit juice whilst taking Triplixam 4mg/1.25mg/5mg Tablet as it might increase the blood levels of amlodipine; this can lead to an unpredictable increase in the blood pressure-lowering effect of Triplixam 4mg/1.25mg/5mg Tablet . Inform your doctor if you are on a salt-restricted diet, use salt substitutes or if you are taking potassium supplements.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid consuming alcohol as it might cause increased dizziness.

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Pregnancy

Caution

Triplixam 4mg/1.25mg/5mg Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Please consult your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Triplixam 4mg/1.25mg/5mg Tablet is not recommended for breastfeeding mothers. Talk to your doctor if you have any concerns.

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Driving

Caution

Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver problems or any concerns regarding this. Avoid taking Triplixam 4mg/1.25mg/5mg Tablet if you have severe liver disease or hepatic encephalopathy.

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Kidney

Caution

Dose adjustment may be needed. Avoid taking Triplixam 4mg/1.25mg/5mg Tablet if you have severe kidney problems. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Triplixam 4mg/1.25mg/5mg Tablet is not recommended for children as safety and effectiveness have not been established.

About Triplixam 4mg/1.25mg/5mg Tablet

Triplixam 4mg/1.25mg/5mg Tablet belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension). High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Triplixam 4mg/1.25mg/5mg Tablet helps lower the blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke.  
 
Triplixam 4mg/1.25mg/5mg Tablet contains Indapamide, Amlodipine, and Perindopril erbumine. Indapamide lowers blood pressure by increasing the amount of urine produced by the kidneys. Amlodipine relaxes the blood vessels, thereby improves blood flow. Perindopril erbumine widens the blood vessels, making it easier for the heart to pump blood through them. Together, Triplixam 4mg/1.25mg/5mg Tablet helps treat hypertension.
 
You are advised to take Triplixam 4mg/1.25mg/5mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as oedema, headache, dizziness, flushing, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Triplixam 4mg/1.25mg/5mg Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Triplixam 4mg/1.25mg/5mg Tablet is not recommended for breastfeeding mothers and children. Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Triplixam 4mg/1.25mg/5mg Tablet

Hypertension (high blood pressure).

Medicinal Benefits Mweb

Medicinal Benefits

Triplixam 4mg/1.25mg/5mg Tablet is a combination of three drugs, namely: Indapamide, Amlodipine, and Perindopril erbumine. Triplixam 4mg/1.25mg/5mg Tablet belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension). Triplixam 4mg/1.25mg/5mg Tablet helps lower blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke. Indapamide is a diuretic that lowers blood pressure by increasing the amount of urine produced by the kidneys. Amlodipine is a calcium channel blocker that relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine is an angiotensin-converting enzyme inhibitor that widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Triplixam 4mg/1.25mg/5mg Tablet helps treat hypertension.

Directions for Use

Take Triplixam 4mg/1.25mg/5mg Tablet before a meal. Swallow Triplixam 4mg/1.25mg/5mg Tablet as a whole with water; do not crush, break or chew it.

Side Effects of Triplixam 4mg/1.25mg/5mg Tablet

  • Oedema
  • Headache
  • Dizziness
  • Flushing
  • Tiredness
  • Weakness
  • Nausea
  • Vomiting

Drug Warnings

Do not take Triplixam 4mg/1.25mg/5mg Tablet if you are allergic to any of its contents; if you have angioedema, severe liver/kidney problems, liver encephalopathy, severe water retention, low blood pressure, or low blood potassium. Inform your doctor if you have diabetes, heart problems, gout, parathyroid gland problems, heart failure, collagen disease, atherosclerosis (hardening of arteries), excess acid in the blood, liver/kidney problems, if you are on a low-salt diet, if you are taking lithium/potassium-sparing diuretics, low blood pressure in the brain, or if you are taking any other blood pressure-lowering medicines. Triplixam 4mg/1.25mg/5mg Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Triplixam 4mg/1.25mg/5mg Tablet is not recommended for breastfeeding mothers and children. Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness, so drive with caution. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Using Triplixam 4mg/1.25mg/5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Combining Aliskiren with Triplixam 4mg/1.25mg/5mg Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
IndapamideDroperidol
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking Droperidol with Triplixam 4mg/1.25mg/5mg Tablet can lead to severe heart problems.

How to manage the interaction:
Taking Droperidol with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking Protriptyline along with Triplixam 4mg/1.25mg/5mg Tablet can lead to serious heart problems.

How to manage the interaction:
Taking Protriptyline with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Taking Triplixam 4mg/1.25mg/5mg Tablet with Thioridazine can increase the risk of heart problems.

How to manage the interaction:
Taking Thioridazine with Triplixam 4mg/1.25mg/5mg Tablet is not recommended, but can be taken if prescribed by the doctor.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Using Triplixam 4mg/1.25mg/5mg Tablet and phenytoin together may drastically lower Triplixam 4mg/1.25mg/5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Triplixam 4mg/1.25mg/5mg Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Coadministration of Triplixam 4mg/1.25mg/5mg Tablet and carbamazepine together may significantly reduce Triplixam 4mg/1.25mg/5mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Triplixam 4mg/1.25mg/5mg Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Using Triplixam 4mg/1.25mg/5mg Tablet and primidone together may lower Triplixam 4mg/1.25mg/5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Triplixam 4mg/1.25mg/5mg Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Co-administration of Triplixam 4mg/1.25mg/5mg Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Triplixam 4mg/1.25mg/5mg Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
How does the drug interact with Triplixam 4mg/1.25mg/5mg Tablet:
Coadministration of Triplixam 4mg/1.25mg/5mg Tablet and rifampicin together may lower Triplixam 4mg/1.25mg/5mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Triplixam 4mg/1.25mg/5mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LITHIUM
  • DANTROLENE
  • ESTRAMUSTINE
  • SACUBITRIL+VALSARTAN
  • TRIAMTERENE
  • AMILORIDE
  • CICLOSPORIN
  • ALISKIREN

Habit Forming

No

Special Advise

  • Regular monitoring of blood pressure levels, kidney function and electrolyte levels while taking Triplixam 4mg/1.25mg/5mg Tablet is advised.
  • If you are due to have any surgery, inform the doctor that you are taking Triplixam 4mg/1.25mg/5mg Tablet

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet. 
  • Exercise regularly.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Practice meditation or yoga as it helps in managing stress.

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