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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy

Composition :

ACICLOVIR-250MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - UNI0052

Author Details

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About Univir 250 Injection

Uses of Univir 250 Injection

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Univir 250 Injection

Drug Warnings

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Univir 250 Injection:
Co-administration of Cidofovir with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Univir 250 Injection with Cidofovir is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Univir 250 Injection:
Coadministration of Univir 250 Injection with Tenofovir Disoproxil may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Univir 250 Injection with Tenofovir disoproxil can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Univir 250 Injection:
Concomitant use of Univir 250 Injection with Tizanidine can increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Univir 250 Injection with Tizanidine can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, excessive sweating, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Univir 250 Injection:
Coadministration of Univir 250 Injection with Amphotericin B can increase the risk or severity of kidney disorder.

How to manage the interaction:
Taking Univir 250 Injection with Amphotericin b together can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience irregular urination, muscle ache, shortness if breath, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirMetrizamide
Severe
How does the drug interact with Univir 250 Injection:
Coadministration of Metrizamide in contrast with Univir 250 Injection may increase the risk or severity of kidney disorder.

How to manage the interaction:
Before undergoing any imaging procedure, let your doctor know you are on Univir 250 Injection treatment. Look out for signs such as vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or weakness. Consult the doctor immediately.
How does the drug interact with Univir 250 Injection:
Coadministration of Univir 250 Injection with Everolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Univir 250 Injection with Everolimus together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Univir 250 Injection:
Coadministration of Univir 250 Injection with Tenofovir alafenamide may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Univir 250 Injection with tenofovir alafenamide can result in an interaction. However, if the benefits outweigh the risks, your doctor will prescribe them. Contact a doctor immediately if you experience symptoms such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medication without consulting your doctor.
AciclovirIodamide
Severe
How does the drug interact with Univir 250 Injection:
Coadministration of Iodamide contrast with Univir 250 Injection may increase the risk or severity of kidney injury.

How to manage the interaction:
Before undergoing any imaging procedure let your doctor know you are on Univir 250 Injection treatment.
How does the drug interact with Univir 250 Injection:
Coadministration of Univir 250 Injection with Sirolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Univir 250 Injection with Sirolimus can result in an interaction, it can be taken if your doctor has advised it. However, if you experience vomiting, a decrease in hunger, irregular urine, weight gain or loss, swelling, difficulty breathing, muscle pain, or weakness, consult a doctor.
How does the drug interact with Univir 250 Injection:
Co-administration of Univir 250 Injection with tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Coadministration of Univir 250 Injection with Tacrolimus can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACICLOVIR-250MGOther disorders of kidney and ureter, not elsewhere classified
Severe
ACICLOVIR-250MGVolume depletion
Moderate

Drug-Diseases Interactions

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ACICLOVIR-250MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Univir 250 Injection:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.

How to manage the interaction:
The use of Univir 250 Injection in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACICLOVIR-250MGVolume depletion
Moderate
How does the disease interact with Univir 250 Injection:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.

How to manage the interaction:
Univir 250 Injection is excreted through the kidneys, dehydration may cause damage to kidney functions. Univir 250 Injection infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACICLOVIR-250MGCare involving dialysis
Moderate
How does the disease interact with Univir 250 Injection:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.

How to manage the interaction:
Patients undergoing hemodialysis should be given Univir 250 Injection after completing hemodialysis as hemodialysis removes 60% of Univir 250 Injection from the body.

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