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Our body breaks down anticancer agents like ifosfamide or cyclophosphamide to form a chemical known as acrolein, which can harm and irritate the bladder. UROMITEXAN 100MG INJECTION 2ML works by making this natural chemical less harmful or toxic. However, UROMITEXAN 100MG INJECTION 2ML does not change ifosfamide's anti-cancer effects.
No, UROMITEXAN 100MG INJECTION 2ML should not be taken with an anti-coagulant like warfarin, heparin or coumarin as it might increase the risk of bleeding and lead to serious complications.
An autoimmune disorder is a condition in which the immune system attacks healthy parts of the body and causes pain, swelling, and damage. Some autoimmune disorders are rheumatoid arthritis, systemic lupus erythematosus or nephritis.
Please inform your doctor if you observe any change in the urine colour (like if you have red/pink-coloured urine).
In addition to bladder bleeding in hemorrhagic cystitis, an individual might also experience bladder wall scarring, decreased bladder size (atrophy), severe systemic infection (urosepsis), and urinary obstruction.
Alcohol
Caution
Avoid consumption of alcohol while on treatment with UROMITEXAN 100MG INJECTION 2ML as it may lead to serious side effects.
Pregnancy
Unsafe
UROMITEXAN 100MG INJECTION 2ML is not recommended to be used in pregnancy as it may cause serious side effects. Use effective birth control measures before starting the treatment with Ifosamide and for 3 months after completing the treatment. If you get pregnant while you are receiving UROMITEXAN 100MG INJECTION 2ML, inform your doctor.
Breast Feeding
Unsafe
UROMITEXAN 100MG INJECTION 2ML should not be used if you are breastfeeding as it is known to pass through the breast milk and harm your infant. Do not breastfeed for at least one week following your last dosage of mesna or ifosfamide.
Driving
Unsafe
UROMITEXAN 100MG INJECTION 2ML is known to cause blurred vision and drowsiness. So, do not drive or operate machinery, which requires mental alertness.
Liver
Caution
Let your doctor know if you have any history of liver diseases before receiving UROMITEXAN 100MG INJECTION 2ML.
Kidney
Caution
Let your doctor know if you have any history of kidney diseases before receiving UROMITEXAN 100MG INJECTION 2ML. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Children
Caution
The safety and efficacy of UROMITEXAN 100MG INJECTION 2ML in children have not been established. Moreover, UROMITEXAN 100MG INJECTION 2ML contains benzyl alcohol, which is known to cause a gasping syndrome in children. Hence, use is not recommended.
About UROMITEXAN 100MG INJECTION 2ML
UROMITEXAN 100MG INJECTION 2ML belongs to a class of medication known as 'cytoprotectant' primarily used to prevent Hemorrhagic cystitis (a condition that causes bleeding in the urine due to the effect of anticancer agents (Ifosfamide). Our bodies degrade the anticancer drug (ifosfamide) to generate a compound (acrolein) that can injure and irritate the bladder. UROMITEXAN 100MG INJECTION 2ML decreases the risk of bladder irritation and bleeding caused by other anti-cancer drugs.
UROMITEXAN 100MG INJECTION 2ML contains 'Mesna', a chemo-protectant medicine that alters the breakdown of anti-cancer agents (Ifosfamide) found in the urine, making it less toxic. In addition, it binds to other urotoxic metabolites and inhibits their effects on the bladder.
UROMITEXAN 100MG INJECTION 2ML will be administered to your vein by a trained healthcare professional; hence, do not self-administer. In some cases, this medicine may cause certain side effects such as nausea, vomiting, headache, flushing (sense of warmth in the face, ears, neck, and trunk), lethargy, rash, diarrhea, light-headedness, abdominal pain, flu-like symptoms, fever, and injection site reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
UROMITEXAN 100MG INJECTION 2ML is not recommended if you are allergic to it or any of its ingredients. An effective birth control measure should be taken to avoid pregnancy in women of a mother-bearing you’re your doctor may suggest regular urine and blood test while receiving UROMITEXAN 100MG INJECTION 2ML to monitor your CBC (blood cell count). UROMITEXAN 100MG INJECTION 2ML is not indicated for use in hematuria due to other underlying pathological conditions like thrombocytopenia. It is advised to drink at least 1-2 litres of fluid daily while receiving UROMITEXAN 100MG INJECTION 2ML. This medicine should be avoided in pregnant and breastfeeding populations due to serious side effects; hence inform your doctor before administration.
Uses of UROMITEXAN 100MG INJECTION 2ML
Medicinal Benefits
UROMITEXAN 100MG INJECTION 2ML belongs to a class of medication known as 'chemoprotectant' primarily used to prevent bleeding into the urine by a particular anticancer medicine known as ifosfamide (ifosfamide-induced hemorrhagic cystitis). It also reduces the risk of inflammation and bleeding in the bladder by receiving anti-cancer medication. It contains Mesna, which works by reacting chemically with the urotoxic ifosfamide (anti-cancer medicines) metabolites, resulting in their detoxification. In addition, it binds to other urotoxic metabolites and inhibits their effects on the bladder.
Directions for Use
Side Effects of UROMITEXAN 100MG INJECTION 2ML
Drug Warnings
Do not take this injection if you are allergic to UROMITEXAN 100MG INJECTION 2ML or any of its ingredients. An effective birth control method should be used to avoid pregnancy in women of childbearing age. Maintain a three-month gap between your last dose of UROMITEXAN 100MG INJECTION 2ML and your next pregnancy. Regular urine and blood test should be done while receiving UROMITEXAN 100MG INJECTION 2ML to monitor your CBC (blood cell count). It is not indicated for use in hematuria due to other underlying pathological conditions like thrombocytopenia. This medicine is known to cause blurry vision and dizziness, so do not drive or operate machinery.
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