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  3. Valera M 1000 Tablet 15's

Valera M 1000 Tablet 15's, Pack of 15 TABLET S
Valera M 1000 Tablet 15's, Pack of 15 TABLET S
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Composition :

EVOGLIPTIN-5MG + METFORMIN-1000MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Valera M 1000 Tablet

Valera M 1000 Tablet belongs to the group of medications called 'antidiabetic agents' used as an adjunct to diet and exercise to improve glycaemic control in adult patients with type 2 diabetes mellitus. This medication improves glycaemic control in diabetic patients who do not react well to metformin alone. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. 

Valera M 1000 Tablet is a combination of two medicines: Metformin and Evogliptin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. On the other side, Evogliptin works by increasing insulin release from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and post-meal sugar levels. Thereby, Valera M 1000 Tablet reduces sugar levels in the body.

Take Valera M 1000 Tablet as prescribed. You are advised to take Valera M 1000 Tablet for as long as your doctor has advised. In some cases, Valera M 1000 Tablet may cause nausea, vomiting, diarrhoea, headache, stomach ache, respiratory infection, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, consult your doctor.

Do not take Valera M 1000 Tablet if you are allergic to any of its contents. Valera M 1000 Tablet may cause lactic acidosis (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycaemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Valera M 1000 Tablet

Type 2 Diabetes Mellitus

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Valera M 1000 Tablet is indicated for managing type 2 diabetes with the right diet and exercise. Valera M 1000 Tablet is a combination of two medicines: Metformin (biguanide) and Evogliptin (dipeptidyl peptidase-4 inhibitor). Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Evogliptin works by increasing insulin release from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces fasting and post-meal sugar levels. Thereby, Valera M 1000 Tablet reduces sugar levels in the body.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Valera M 1000 Tablet if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). Valera M 1000 Tablet may cause lactic acidosis (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol with Valera M 1000 Tablet as it may increase the risk of lactic acidosis or fast for prolonged periods as it might increase the risk of hypoglycaemia. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

verifiedApollotooltip
MetforminIopamidol
Critical
MetforminIopromide
Critical

Drug-Drug Interactions

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MetforminIopamidol
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iopamidol with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopromide
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iopromide with Valera M 1000 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Valera M 1000 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIopanoic acid
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iopanoic acid with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iodixanol with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIotroxic acid
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iotroxic acid with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Ioglycamic acid with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iopentol with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Valera M 1000 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Valera M 1000 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIofendylate
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Iofendylate with Valera M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Valera M 1000 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Valera M 1000 Tablet:
Co-administration of Valera M 1000 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Valera M 1000 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat at regular intervals. Do not take a long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise weekly.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole-grain foods. Increase fruits, vegetables and other fibre-enriched foods in your diet.
  • Reduce saturated fat foods such as chips, crisps, pastries, biscuits, and samosas.
  • Choose omega-3 fatty acid-containing oils for daily cooking. 
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
  • Avoid drinking alcohol while on Valera M 1000 Tablet . It increases the risk of hypoglycaemia (a decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts various organs).
  • Try to quit smoking and reduce your intake of carbohydrate-rich food like potatoes, rice, mangoes, bread, sugar, etc.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Valera M 1000 Tablet contains Metformin and Evogliptin. Metformin works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin. Evogliptin works by increasing insulin release from the pancreas and decreasing the hormones that raise blood sugar levels. Altogether Valera M 1000 Tablet reduces sugar levels in the body.

Hypoglycemia refers to low blood glucose levels. Valera M 1000 Tablet may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, do intense exercise, or take other antidiabetic medicine along with Valera M 1000 Tablet .

If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. Always carry glucose tablets or sugar candies with you.

Do not discontinue taking Valera M 1000 Tablet without consulting your doctor. Take Valera M 1000 Tablet for as long as it has been advised by the doctor. If you experience any difficulty while taking Valera M 1000 Tablet , consult a doctor.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

Valera M 1000 Tablet can assist in maintaining a consistent blood sugar level and lower your risk of diabetes-related issues in the future.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • PREDNISOLONE
  • FUROSEMIDE
  • ENALAPRIL
  • PERINDOPRIL
  • TESTOSTERONE
  • PROGESTERONE
  • OESTROGEN

Special Advise

  • Keep taking Valera M 1000 Tablet even if your blood sugar levels are controlled.
  • Take short, frequent meals, and avoid prolonged fasting when taking Valera M 1000 Tablet . Beware of hypoglycaemia symptoms, including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.

Disease/Condition Glossary

Type 2 diabetes mellitus: Type 2 diabetes mellitus is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilization of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin; in later stages, your body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite and dry mouth. If not properly treated, this condition may worsen over time and cause toxic effects.

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