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  3. Valprol Syrup 200 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Synonym :

VALPROIC ACID

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Valprol Syrup

Valprol Syrup belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits and bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 

Valprol Syrup contains 'Sodium valproate', which decreases the brain's excessive and abnormal nerve activity. Thus, it helps in controlling seizures. Valprol Syrup increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thus, it helps treat bipolar disorder. 

Use Valprol Syrup as prescribed by your doctor. Sometimes, it may cause certain side effects such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually. However, if the side effects persist or worsen, inform your doctor immediately.

Before using Valprol Syrup , inform your doctor about your children's medical conditions, sensitivities, and all medications used. To treat your condition effectually, continue using Valprol Syrup for as long as your doctor has prescribed. Valprol Syrup should be gradually withdrawn, so please do not stop using Valprol Syrup without consulting your doctor. Consult your doctor immediately if you observe any suicidal tendencies in your children.

Uses of Valprol Syrup

Epilepsy, Bipolar disorder

Directions for Use

Syrup/Oral Solution: Give this medicine to your child as directed by your physician or per instructions in the package leaflet.

Medicinal Benefits

Sodium valproate reduces the brain's excessive and unusual nerve activity. On the other hand, it helps to raise the quantity of a chemical substance called GABA in the brain, which helps to stop nerve transmission and has a calming effect. Thus, it aids in the treatment of epilepsy, seizures, and fits, as well as bipolar disorder.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

The presence of other medical problems or using other medications may affect the use of this medicine. So, before using Valprol Syrup , let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use this medication on your own unless prescribed by the doctor. Do not exceed the stated recommended dose.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valprol Syrup 200 ml:
Combining Sodium phenylbutyrate and Valprol Syrup 200 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valprol Syrup 200 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Meropenam and Valprol Syrup 200 ml together can reduce the effect of Valprol Syrup 200 ml.

How to manage the interaction:
Co-administration of Meropenam and Valprol Syrup 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valprol Syrup 200 ml:
Using buprenorphine together with Valprol Syrup 200 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valprol Syrup 200 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Valprol Syrup 200 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valprol Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Leflunomide and Valprol Syrup 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valprol Syrup 200 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Teriflunomide and Valprol Syrup 200 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valprol Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Vorinostat with Valprol Syrup 200 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valprol Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Valprol Syrup 200 ml:
The combined use of Ertapenem and Valprol Syrup 200 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valprol Syrup 200 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Ketamine and Valprol Syrup 200 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valprol Syrup 200 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Valprol Syrup 200 ml:
Co-administration of Lithium with Valprol Syrup 200 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valprol Syrup 200 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your children's living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Let your child rest well and sleep well.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

ANTICONVULSANT

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Valprol Syrup decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Valprol Syrup helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Do not discontinue Valprol Syrup without consulting your doctor. To treat your child's condition effectually, continue using Valprol Syrup for as long as prescribed. Do not be reluctant to speak with your doctor if your child experiences difficulty while taking Valprol Syrup ; your doctor will gradually reduce the dose to avoid worsening seizures.

Valprol Syrup may change the results of liver enzymes and urine and blood tests. Inform the person doing the tests that your child using Valprol Syrup .

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PRIMIDONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • TOPIRAMATE
  • ACETAZOLAMIDE
  • LAMOTRIGINE
  • FELBAMATE
  • WARFARIN
  • ZIDOVUDINE
  • LOPINAVIR
  • RITONAVIR
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • NIMODIPINE
  • PROPOFOL
  • OESTROGEN
  • LEVONORGESTREL
  • MEFLOQUINE
  • CHLOROQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CHOLESTYRAMINE
  • CLONAZEPAM
  • DIAZEPAM

Special Advise

Maintain all scheduled follow-up appointments with your healthcare practitioner.

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a nervous system disorder that occurs due to disturbed nerve cell activity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows.

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