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  3. Vectibix 100 mg Infusion 5 ml

Vectibix 100 mg Infusion 5 ml, Pack of 1 INJECTION
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Lakshmithulasi Yarragunta , Pharm-D (PB)
Non returnable*
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Whats That

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Synonym :

MONOCLONAL ANTIBODIES

Composition :

PANITUMUMAB-100MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Vectibix 100 mg Infusion 5 ml

Vectibix 100 mg Infusion 5 ml belongs to a class of monoclonal antibodies. It is used alone or with other anticancer medicines to treat wild-type RAS metastatic colorectal cancer (mCRC). Metastatic colorectal cancer (mCRC) is a type of cancer of the colon or rectum that has spread to other areas of the body.

Vectibix 100 mg Infusion 5 ml contains Panitumumab, which works by slowing or stopping the growth of cancer cells. As a result, it prevents the cancer from spreading.

Vectibix 100 mg Infusion 5 ml will be administered under the supervision of a physician qualified by training and an experienced oncologist. The most frequent side effects of Vectibix 100 mg Infusion 5 ml when taken with other chemotherapy medications include diarrhea, paronychia (nail inflammation), fatigue, nausea, and diarrhea; stomatitis (oral mucosal inflammation and redness), mucosal inflammation, asthenia (abnormal physical weakness), anorexia, hypomagnesemia (an electrolyte disturbance), hypokalemia, rash, skin rash, itchiness, and dry skin. You should talk to your doctor if these side effects persist or worsen.

Notify your doctor of any food or medication allergies or hypersensitivity reactions before taking the Vectibix 100 mg Infusion 5 ml. Vectibix 100 mg Infusion 5 ml may cause fetal harm when administered to a pregnant woman. Before beginning treatment, discuss effective contraception with your healthcare professional. Inform them immediately if you or your partner become pregnant while undergoing therapy. Breastfeeding is not recommended while taking panitumumab. 

Uses of Vectibix 100 mg Infusion 5 ml

Metastatic colorectal cancer (mCRC)

Directions for Use

Vectibix 100 mg Infusion 5 ml will be administered by a trained and experienced oncologist.

Medicinal Benefits

Vectibix 100 mg Infusion 5 ml contains Panitumumab, a monoclonal antibody. It is used alone or in conjunction with other anticancer medications to treat metastatic colorectal cancer (mCRC). It works by slowing or preventing the growth of cancer cells. As a result, it inhibits the cancer from spreading.

Storage

Store in a cool and dry place away from sunlight
Side effects of Vectibix 100 mg Infusion 5 ml
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Know your allergens that cause dermatitis and avoid them.
  • Use fragrance-free detergents and soaps.
  • Apply moisturizer after taking bath to retain moisture in the skin.
  • Apply cool, moist compresses to the rash.
  • Talk to your doctor about creams and ointments to manage your dermatitis.
  • Avoid the use of abrasive scrubs, astringents, and soaps that might irritate skin.
  • Contact a physician or dermatologist to treat any medical concerns if the skin symptoms worsen or continue.
  • Drink enough water throughout the day to maintain hydrated, plump skin.
  • If the skin symptoms persist or worsen, consult a doctor or dermatologist
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Soak the infected nail in warm water for 10 to 20 minutes, a few times a day.
  • Apply topical antibiotic ointment as advised by the doctor.
  • Avoid irritants and excessive moisture.
  • Maintaining adequate hydration will help you control your magnesium levels and improve your general health.
  • Maintain a diet high in magnesium-rich foods such as spinach, almonds, chickpeas and brown rice.
  • Limit your alcohol intake because too much of it lowers your magnesium levels.
  • Plan blood testing on a regular basis to monitor magnesium levels.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Before taking Vectibix 100 mg Infusion 5 ml, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions. The dosage of this medicine will be based on your health condition. Your doctor may adjust your dose during therapy based on the treatment results. Vectibix 100 mg Infusion 5 ml may cause infusion reactions, interstitial lung disease (ILD), ocular toxicity, and dermatologic or soft tissue toxicity. Hence, inform the doctor immediately if you suffer any side effects. If therapy needs to be stopped, your doctor will make that decision. Vectibix 100 mg Infusion 5 ml is recommended not to be used in pregnant women. Therefore, if you become pregnant while on treatment with Panitumumab, tell your doctor immediately. Breastfeeding is not recommended while taking panitumumab. Alcohol should be avoided during treatment with this medicine. Drive only if alert, as the Vectibix 100 mg Infusion 5 ml may cause nausea or tiredness.

Drug-Drug Interactions

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PanitumumabAmiodarone
Severe

Drug-Drug Interactions

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PanitumumabAmiodarone
Severe
How does the drug interact with Vectibix 100 mg Infusion 5 ml:
Coadministration of Amiodarone together with Vectibix 100 mg Infusion 5 ml may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Vectibix 100 mg Infusion 5 ml interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the best meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain a proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Performing yoga may also help improve both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried foods, processed meats, refined carbs, and added sugars.

Habit Forming

No

Therapeutic Class

MONOCLONAL ANTIBODIES

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Lakshmithulasi YarraguntaDoctor badge

Reviewed By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Last Updated

Jul 8, 2025 | 9:50 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Vectibix 100 mg Infusion 5 ml contains Panitumumab, which works by slowing or stopping the growth of cancer cells. Thus, it prevents the cancer from spreading.

Attend all your doctor's appointments while receiving Vectibix 100 mg Infusion 5 ml to ensure the therapy is effective. Regular blood tests and weight checks must be performed. While taking the Vectibix 100 mg Infusion 5 ml, both men and women should use an effective means of contraception. Do not use any other medications unless prescribed by the doctor.

Magnesium and calcium levels in the blood may significantly fall as a result of Panitumumab. Laboratory testing may be recommended by your doctor both before and during treatment.

Some dietary changes can help you manage side effects; for example, in case of diarrhoea-Choose foods or drinks with sodium (sports drinks or broth) and potassium (bananas and all-natural fruit juices).

Drug-Drug Interactions Checker List

  • AMINOLEVULINIC ACID
  • AMIODARONE
  • DRONEDARONE
  • BEVACIZUMAB
  • ZIPRASIDONE

Special Advise

  • Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to Vectibix 100 mg Infusion 5 ml.
  • Pregnancy testing is recommended prior to starting treatment with Vectibix 100 mg Infusion 5 ml.
  • Do not donate sperm throughout treatment and at least two months after treatment.

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Metastatic colorectal cancer (mCRC): Colorectal cancer is a disease in which cells in the colon or rectum grow out of control. Metastasis means that the cancer cells have spread beyond the colon to other organs. This is also referred to as advanced colon cancer or stage IV colon cancer.

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