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  3. Xoflox TZ 400mg/600mg Tablet

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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
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Xoflox TZ 400mg/600mg Tablet, Pack of 1 Tablet
rxMedicinePrescription drug

Whats That

tooltip

Composition :

NORFLOXACIN-400MG + TINIDAZOLE-600MG

Manufacturer/Marketer :

Mexon Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIBIOTICS

Country of origin

India
Other Info - XO44320

FAQs

Xoflox TZ 400mg/600mg Tablet is a combination of two antibiotics, Norfloxacin, and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Yes, Xoflox TZ 400mg/600mg Tablet may cause minor skin rashes or reactions. In case you are experiencing skin rashes or any such allergic reactions, consult a doctor and stop taking Xoflox TZ 400mg/600mg Tablet.

No, Xoflox TZ 400mg/600mg Tablet is a combination of two antibiotic drugs, it helps resolve moderate to severe infections of the stomach. This medicine is not a pain killer. However, completing a full course of Xoflox TZ 400mg/600mg Tablet may bring relief to discomfort, and stomach pain caused due to infections.

The use of Xoflox TZ 400mg/600mg Tablet is considered to be harmful to patients with known allergy to norfloxacin or tinidazole, or any other excipient present in the medicine. It should preferably be avoided in patients with a history of tendinitis (inflammation of the tendons) or tendon rupture. It is also avoided in patients with some neurological disorders.

No, do not stop taking Xoflox TZ 400mg/600mg Tablet even if you feel better as it is an antibiotic medication and a full course of treatment is necessary. For the best advice, consult your doctor and do as advised.

It is recommended not to take dairy products such as milk, yoghurt, and Xoflox TZ 400mg/600mg Tablet as they might decrease the effectiveness of Xoflox TZ 400mg/600mg Tablet. Please maintain a gap of at least 2 hours between both of them.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Xoflox TZ 400mg/600mg Tablet should not be taken along with alcohol as it is known to cause stomach irritation.

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Pregnancy

Caution

Caution should be exercised, it is advisable to consult a doctor before using it.

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Breast Feeding

Safe if prescribed

Xoflox TZ 400mg/600mg Tablet does not pass on to the child significantly via breast milk, it is advisable to consult a doctor before using it.

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Driving

Caution

Xoflox TZ 400mg/600mg Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Xoflox TZ 400mg/600mg Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Xoflox TZ 400mg/600mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Xoflox TZ 400mg/600mg Tablet is not recommended for children below 12 years of age without a doctor's consent. For children above 12 years, the dose to be adjusted and recommended by a child specialist only.

Product Substitutes

Norflox-TZ RF Tablet 10's

Norflox-TZ RF Tablet 10's

₹117

MRP ₹130

Norflokem TZ Tablet 10's

Norflokem TZ Tablet 10's

₹99

MRP ₹110

NDS Nflox-TZ Tablet 10's

NDS Nflox-TZ Tablet 10's

₹118.8

MRP ₹132

Nore T Tablet 10's

Nore T Tablet 10's

₹114.3

MRP ₹127

Nor-Metrogyl-TZ 400/600 Tablet 10's

Nor-Metrogyl-TZ 400/600 Tablet 10's

₹104.9

MRP ₹116.5

Norcraft TZ Tablet 10's

Norcraft TZ Tablet 10's

₹106.7

MRP ₹118.5

Nirflox-TZ Tablet 10's

Nirflox-TZ Tablet 10's

₹64.8

MRP ₹72

Amebact 400mg/600mg Tablet

Amebact 400mg/600mg Tablet

₹40.5

MRP ₹45

Amibex-Tz Tablet 10's

Amibex-Tz Tablet 10's

₹94.05

MRP ₹104.5

Amodys NT 400mg/600mg Tablet

Amodys NT 400mg/600mg Tablet

₹39.6

MRP ₹44

Mapgyl Plus Tablet

Mapgyl Plus Tablet

₹42.75

MRP ₹47.5

Loc 400 mg/600 mg Tablet

Loc 400 mg/600 mg Tablet

₹46.78

MRP ₹51.98

Loxone TZ 400mg/600mg Tablet

Loxone TZ 400mg/600mg Tablet

₹63

MRP ₹70

Dirend TZ 400mg/600mg Tablet

Dirend TZ 400mg/600mg Tablet

₹43.2

MRP ₹48

Lamizol Plus 400 mg/600 mg Tablet

Lamizol Plus 400 mg/600 mg Tablet

₹32.28

MRP ₹35.87

Lanom 400mg/600mg Tablet

Lanom 400mg/600mg Tablet

₹52.2

MRP ₹58

Reference

  1. https://www.medicines.org.uk/emc/product/1066/smpc#gref
  2. https://medlineplus.gov/diarrhea.html
  3. https://www.healthline.com/health/digestive-health/dysentery

About Xoflox TZ 400mg/600mg Tablet

Xoflox TZ 400mg/600mg Tablet is an antibiotic medication primarily used to treat diarrhoea, dysentery and stomach infections. Dysentery is an intestinal infection generally lasting for three to seven days, causing severe diarrhoea with blood. Diarrhoea is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.

Xoflox TZ 400mg/600mg Tablet is a combination of two antibiotics, Norfloxacin and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Xoflox TZ 400mg/600mg Tablet can be taken with or without food. For best results, take Xoflox TZ 400mg/600mg Tablet as advised by your doctor. Do not chew, crush, or break it. Like all medicines, Xoflox TZ 400mg/600mg Tablet may cause side effects, although not everybody gets them. Some side effects of Xoflox TZ 400mg/600mg Tablet include nausea, dryness of mouth, stomach upset, headache. Most of these side effects of Xoflox TZ 400mg/600mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Xoflox TZ 400mg/600mg Tablet if you are allergic to Xoflox TZ 400mg/600mg Tablet, tinidazole, norfloxacin, or any of its ingredients as it can lead to abnormal neurological signs (such as dizziness, vertigo, difficulty in controlling movements). Norfloxacin present in Xoflox TZ 400mg/600mg Tablet is known to cause tendon rupture, so be cautious while taking Xoflox TZ 400mg/600mg Tablet. In patients having myasthenia gravis (muscle weakness), Xoflox TZ 400mg/600mg Tablet should not be taken as it is known to worsen your condition further. Xoflox TZ 400mg/600mg Tablet should not be taken if you are pregnant or breastfeeding. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Xoflox TZ 400mg/600mg Tablet. Consumption of alcohol, along with Xoflox TZ 400mg/600mg Tablet, can cause stomach irritation and increased drowsiness.

Uses of Xoflox TZ 400mg/600mg Tablet

Diarrhoea, Dysentry, Stomach infections

Medicinal Benefits Mweb

Medicinal Benefits

Xoflox TZ 400mg/600mg Tablet is primarily used to treat dysentery, diarrhoea, and upset stomach. Additionally, when Xoflox TZ 400mg/600mg Tablet is taken as a course, as directed by a doctor, it helps eradicate and prevent the return of infections caused due to microorganisms responsible for digestive tract infections. It is a combination of two antibiotics, norfloxacin, and tinidazole. Xoflox TZ 400mg/600mg Tablet plays a vital role in treating diarrhoea and dysentery. Norfloxacin helps by preventing the bacterial cells from dividing and hence killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects of Xoflox TZ 400mg/600mg Tablet

  • Nausea
  • Dryness of mouth
  • Stomach upset
  • Nausea
  • Headache
  • Metallic taste or change in taste
  • Loss of appetite, weakness
  • Skin rash or itching

Drug Warnings

Do not take Xoflox TZ 400mg/600mg Tablet if you are allergic to Xoflox TZ 400mg/600mg Tablet, tinidazole, norfloxacin, or any of its ingredients. Inform your doctor if you have any kidney or liver problem, any neurologic problem, Norfloxacin present in Xoflox TZ 400mg/600mg Tablet is known to cause tendon rupture, so be cautious while taking Xoflox TZ 400mg/600mg Tablet. In patients having myasthenia gravis (muscle weakness), Xoflox TZ 400mg/600mg Tablet should not be taken as it is known to worsen your condition further. Xoflox TZ 400mg/600mg Tablet should not be taken if you are pregnant or breastfeeding. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Diarrhoea can cause dehydration, so please increase the intake of fluids. If you have constipation or have blood in stools, do not take Xoflox TZ 400mg/600mg Tablet. Consumption of alcohol, along with Xoflox TZ 400mg/600mg Tablet, can cause stomach irritation and increased drowsiness.

Drug-Drug Interactions

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NorfloxacinSotalol
Critical
NorfloxacinBepridil
Critical

Drug-Drug Interactions

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NorfloxacinSotalol
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Coadministration of Xoflox TZ 400mg/600mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Xoflox TZ 400mg/600mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Using bepridil together with Xoflox TZ 400mg/600mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Xoflox TZ 400mg/600mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinCisapride
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Coadministration of Xoflox TZ 400mg/600mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Xoflox TZ 400mg/600mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinAmiodarone
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
The combination of Amiodarone and Xoflox TZ 400mg/600mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Xoflox TZ 400mg/600mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Using Mesoridazine together with Xoflox TZ 400mg/600mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Xoflox TZ 400mg/600mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinDisopyramide
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Coadministration of Xoflox TZ 400mg/600mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Xoflox TZ 400mg/600mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
TinidazoleAmprenavir
Critical
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Co-administration of Amprenavir and Xoflox TZ 400mg/600mg Tablet can increase the risk or severity of developing serious side effects.

How to manage the interaction:
Co-administration of Amprenavir and Xoflox TZ 400mg/600mg Tablet is generally avoided, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like flushing, severe headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, excessive sweating, dizziness, lightheadedness, blurred vision, or confusion. Rarely, more severe reactions may include unconsciousness or convulsions, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
NorfloxacinToremifene
Severe
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Using toremifene together with Xoflox TZ 400mg/600mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Xoflox TZ 400mg/600mg Tablet with Toremifene can result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like an irregular heartbeat, dizziness, fainting, or difficulty breathing, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
NorfloxacinTolbutamide
Severe
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Coadministration of Xoflox TZ 400mg/600mg Tablet with Tolbutamide may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Xoflox TZ 400mg/600mg Tablet can be taken with Tolbutamide if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised.
NorfloxacinIvabradine
Severe
How does the drug interact with Xoflox TZ 400mg/600mg Tablet:
Coadministration of Ivabradine with Xoflox TZ 400mg/600mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ivabradine with Xoflox TZ 400mg/600mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MG+TINIDAZOLE-600MGCalcium rich foods

Drug-Food Interactions

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NORFLOXACIN-400MG+TINIDAZOLE-600MGCalcium rich foods
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt

How to manage the interaction:
Consumption of food containing minerals like magnesium, zinc, and calcium reduces the absorption of Tinidazole and Norfloxacin, resulting in reduced medication efficacy in treating infections. It is advised to take Tinidazole and Norfloxacin on an empty stomach and to avoid consuming food or products containing minerals one hour before and 2 hours after consuming Tinidazole and Norfloxacin.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • WARFARIN
  • PROBENECID
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • TRIMETHOPRIM
  • AMOXICILLIN
  • METRONIDAZOLE
  • NITROFURANTOIN
  • ERYTHROMYCIN
  • CALCIUM
  • CHOLERA VACCINE
  • TYPHOID VACCINE
  • SULFAMETHOXAZOLE

Habit Forming

No

Special Advise

  • Diarrhea can cause dehydration, so please increase the intake of fluids.
  • Norfloxacin present in Xoflox TZ 400mg/600mg Tablet is known to cause tendon rupture, so be cautious while taking Xoflox TZ 400mg/600mg Tablet if you have a tendon rupture history.
  • Norfloxacin present in Xoflox TZ 400mg/600mg Tablet may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.

  • You must avoid being in the sunlight for too long as Xoflox TZ 400mg/600mg Tablet may make you more sensitive to the sun.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder antibiotic's absorption.
  • Avoid consumption of alcohol to treat your condition effectively.
  • Avoid usage of tobacco.
  • To cure your condition effectually, complete the full course of Xoflox TZ 400mg/600mg Tablet even though you find symptomatic relief.

Xoflox TZ 400mg/600mg Tablet Substitute

Substitutes safety advice

  • Norflox-TZ RF Tablet 10's

    by Others

    ₹11.70per tablet

  • Norflokem TZ Tablet 10's

    by Others

    ₹9.90per tablet

  • NDS Nflox-TZ Tablet 10's

    by Others

    ₹11.88per tablet

  • Nore T Tablet 10's

    by AYUR

    ₹11.43per tablet

  • Nor-Metrogyl-TZ 400/600 Tablet 10's

    by Others

    ₹10.49per tablet
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