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  3. Xoritas 1.5 gm Injection 1's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

CEFUROXIME-1500MG

Manufacturer/Marketer :

Aequitas Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- BACTERIALS

Country of origin

India

Manufacturer/Marketer address

Unit No. 207, Neelkanth Commercial Centre, 122, Sahar Road, Andheri (East), Mumbai - 400099
Other Info - XOR0017

Author Details

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FAQs

Xoritas 1.5 gm Injection 1's works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

After taking an antibiotic, you may need to wait up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also affect the working of antibiotics.

Xoritas 1.5 gm Injection 1's is used to treat bacterial infections and does not treat viral infections such as cough, flu or cold.

Xoritas 1.5 gm Injection 1's may interact with birth control pills and lower its efficiency. Inform your doctor if you use any birth control pills.

Xoritas 1.5 gm Injection 1's may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience a severe, persistent diarrhoea, or if you find blood or mucus in stools, consult your doctor immediately. Do not take anti-diarrhoeal medicine on your own.

Disclaimer

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Alcohol

Caution

It is not known if alcohol affects Xoritas 1.5 gm Injection 1's. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

Please consult the doctor as there are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Xoritas 1.5 gm Injection 1's.

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Driving

Caution

Xoritas 1.5 gm Injection 1's may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Limited information is available regarding the use of Xoritas 1.5 gm Injection 1's in patients suffering from liver impairment. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney problems.

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Children

Safe if prescribed

Xoritas 1.5 gm Injection 1's can be given safely to children provided a child specialist has prescribed the dose.

About Xoritas 1.5 gm Injection 1's

Xoritas 1.5 gm Injection 1's belongs to the class of cephalosporin antibiotics indicated to treat a wide range of bacterial infections including lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia (blood infection), meningitis (infection of brain and spinal cord), gonorrhoea (sexually transmitted infections), bone and joint infections. Xoritas 1.5 gm Injection 1's is also used to prevent infections during surgery. 

Xoritas 1.5 gm Injection 1's is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

A healthcare expert will administer Xoritas 1.5 gm Injection 1's; do not self-administer. In some cases, Xoritas 1.5 gm Injection 1's may cause side effects such as diarrhoea, nausea, vomiting, pain, and swelling at the site of injection. Most of these side effects do not require medical attention and resolve over time. However, if the side effects persist or worsen, consult your doctor.

Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions. Consult your doctor if you are pregnant, breastfeeding, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Xoritas 1.5 gm Injection 1's therapy against the risk to your baby. Xoritas 1.5 gm Injection 1's may cause dizziness, so drive only if you are alert.

Uses of Xoritas 1.5 gm Injection 1's

Bacterial infections

Medicinal Benefits Mweb

Medicinal Benefits

Xoritas 1.5 gm Injection 1's is used to treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Xoritas 1.5 gm Injection 1's is also used to prevent infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. Xoritas 1.5 gm Injection 1's is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

Directions for Use

Xoritas 1.5 gm Injection 1's will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Xoritas 1.5 gm Injection 1's

  • Pain and swelling at the site of injection
  • Diarrhoea
  • Nausea
  • Vomiting

Drug Warnings

Do not take Xoritas 1.5 gm Injection 1's if you are allergic to any of the contents. Consult your doctor if you are pregnant or breastfeeding. Inform your doctor if you have kidney or liver problems. Xoritas 1.5 gm Injection 1's may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience a severe, persistent diarrhoea, or if you find blood or mucus in stools, consult your doctor immediately. Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions.

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Xoritas 1.5 gm Injection:
Co-administration of Xoritas 1.5 gm Injection may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Xoritas 1.5 gm Injection. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Xoritas 1.5 gm Injection:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Xoritas 1.5 gm Injection.

How to manage the interaction:
Although taking Xoritas 1.5 gm Injection and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Xoritas 1.5 gm Injection:
Co-administration of Dalteparin and Xoritas 1.5 gm Injection can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Xoritas 1.5 gm Injection with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xoritas 1.5 gm Injection:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CEFUROXIME-1500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-1500MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-1500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Xoritas 1.5 gm Injection:
Colitis: In some cases the use of Xoritas 1.5 gm Injection may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Xoritas 1.5 gm Injection should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-1500MGChronic kidney disease
Moderate
How does the disease interact with Xoritas 1.5 gm Injection:
Renal dysfunction: Xoritas 1.5 gm Injection is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Xoritas 1.5 gm Injection as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-1500MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Xoritas 1.5 gm Injection:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Xoritas 1.5 gm Injection after dialysis or an additional dosage to be administered.

How to manage the interaction:
Xoritas 1.5 gm Injection serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-1500MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Xoritas 1.5 gm Injection:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Xoritas 1.5 gm Injection if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Xoritas 1.5 gm Injection should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-1500MGOther diseases of liver
Moderate
How does the disease interact with Xoritas 1.5 gm Injection:
liver disease: With Xoritas 1.5 gm Injection, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-1500MGOther diseases of liver
Moderate
How does the disease interact with Xoritas 1.5 gm Injection:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

Drug-Drug Interactions Checker List

  • GENTAMICIN
  • NEOMYCIN
  • FUROSEMIDE
  • PROBENECID
  • WARFARIN
  • LEVONORGESTREL
  • MEDROXYPROGESTERONE
  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE

Habit Forming

No

Special Advise

  • Regular monitoring of blood count, haemoglobin levels, renal and liver function tests are recommended.
  • Xoritas 1.5 gm Injection 1's might affect lab test results. Inform the person doing the tests that you are taking Xoritas 1.5 gm Injection 1's.

Diet & Lifestyle Advise

  • After completing the course of Xoritas 1.5 gm Injection 1's, probiotics should be taken to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. 
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Xoritas 1.5 gm Injection 1's.
  • Avoid intake of alcoholic beverages with Xoritas 1.5 gm Injection 1's as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Xoritas 1.5 gm Injection 1's in fighting off infections.

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