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  3. Xtandi 40 mg Soft Capsule 120'S

48 Hrs returnable
COD available

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Whats That

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Composition :

ENZALUTAMIDE-40MG

Manufacturer/Marketer :

Astellas Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Astellas Pharma India Pvt Ltd, 301, 3rd Floor, C and B Square, 127 Andheri Kurla Road, Chakala, Andheri East, Mumbai 400 069.
Other Info - XTA0010

FAQs

Most prostate cancers require testosterone to grow. Xtandi 40Mg Capsule contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Xtandi 40Mg Capsule can slow the cancer's growth and cause it to shrink.

Xtandi 40Mg Capsule is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.

In some cases, Xtandi 40Mg Capsule may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.

Enzalutamide, a prostate cancer medication, is used to treat prostate cancer.

Seizures may occur in patients receiving Xtandi 40Mg Capsule . So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.

Yes, Enzalutamide was generally a well-tolerated medication. Take Xtandi 40Mg Capsule pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Xtandi 40Mg Capsule unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Xtandi 40Mg Capsule therapy or adjust your Xtandi 40Mg Capsule dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Xtandi 40Mg Capsule .

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Pregnancy

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Unsafe

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Caution

Xtandi 40Mg Capsule may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Consult your doctor

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Xtandi 40Mg Capsule in pediatric patients have not been established.

About Xtandi 40Mg Capsule

Xtandi 40Mg Capsule belongs to a group of medicines known as androgen receptor inhibitors. It is used to treat prostate cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Xtandi 40Mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Use this medicine as directed by your doctor. You may sometimes experience trouble breathing (pneumonia), weakness or feeling more tired than usual, back pain, diarrhoea, pain in your joints, swelling (in your hands, arms, legs or feet), muscle or bone pain, muscle weakness, headache, cold-like symptoms, dizziness, high blood pressure and trouble falling or staying asleep (insomnia). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Enzalutamide is only for use in men. Men using this Xtandi 40Mg Capsule must use effective birth control whenever they have sex during your treatment and for three months after their final dose. In rare cases, Xtandi 40Mg Capsule may cause seizures, so tell your doctor if you have or have ever had seizures. Because of the risk of seizure associated with Xtandi 40Mg Capsule use, patients should be advised of the risk of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Consumption of alcohol is strictly avoided.

Uses of Xtandi 40Mg Capsule

Prostate Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Xtandi 40Mg Capsule contains Enzalutamide, which belongs to a group of medicines known as androgen receptor inhibitors. Most prostate cancers require testosterone to grow. In men, the testicles produce the majority of testosterone. Adrenal glands (Just above each kidney) produce a small quantity of testosterone. Enzalutamide is preventing testosterone from reaching cancer cells in the prostate. This can inhibit the growth of the cancer and even cause it to shrink.

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Side Effects of Xtandi 40Mg Capsule

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Asthenia/fatigue/weakness
  • Back pain
  • Diarrhea
  • Cold like symptoms
  • Arthralgia (joint pain)
  • Hot flush
  • Peripheral edema
  • Musculoskeletal pain
  • Headache
  • Upper respiratory infection
  • Muscular weakness
  • Dizziness
  • Insomnia
  • Lower respiratory infection
  • Spinal cord compression
  • Cauda equina syndrome
  • Hematuria (blood in urine)
  • Paresthesia (tingling or prickling sensation)
  • Anxiety
  • Hypertension

Drug Warnings

Do not take Xtandi 40Mg Capsule if you are allergic or hypersensitive to any component present in it. You must take Enzalutamide according to the instructions your doctor or pharmacist gives you. You must take Enzalutamide exactly as prescribed by your doctor or pharmacist. You must take the correct dose, not more or less. Consult your healthcare team before discontinuing Xtandi 40Mg Capsule or missing a dose. Talk to your doctor before taking Xtandi 40Mg Capsule if you have severe allergic reactions to medicines or foods or suffer from any medical illness. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Drug-Drug Interactions

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EnzalutamideZiprasidone
Critical
EnzalutamideRanolazine
Critical

Drug-Drug Interactions

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EnzalutamideZiprasidone
Critical
How does the drug interact with Xtandi 40 mg Soft Capsule:
Taking Xtandi 40 mg Soft Capsule with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Xtandi 40 mg Soft Capsule with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideRanolazine
Critical
How does the drug interact with Xtandi 40 mg Soft Capsule:
Taking Xtandi 40 mg Soft Capsule may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Xtandi 40 mg Soft Capsule with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideLurasidone
Critical
How does the drug interact with Xtandi 40 mg Soft Capsule:
Co-administration of Lurasidone with Xtandi 40 mg Soft Capsule may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Xtandi 40 mg Soft Capsule is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideDronedarone
Critical
How does the drug interact with Xtandi 40 mg Soft Capsule:
Co-administration of Xtandi 40 mg Soft Capsule and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Xtandi 40 mg Soft Capsule and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideRegorafenib
Critical
How does the drug interact with Xtandi 40 mg Soft Capsule:
Taking Xtandi 40 mg Soft Capsule with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Xtandi 40 mg Soft Capsule with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideMifepristone
Severe
How does the drug interact with Xtandi 40 mg Soft Capsule:
Co-administration of Xtandi 40 mg Soft Capsule with mifepristone can increase the risk of irregular heart rhythms. Low potassium levels may also result from prolonged therapy with mifepristone

How to manage the interaction:
Taking Xtandi 40 mg Soft Capsule with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, irregular heartbeat, nausea, vomiting, constipation, abdominal cramping, confusion, muscle cramps, numbness or tingling, chest pain, and/or swelling in the legs or feet, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideDolasetron
Severe
How does the drug interact with Xtandi 40 mg Soft Capsule:
Taking Xtandi 40 mg Soft Capsule and Dolasetron together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Xtandi 40 mg Soft Capsule and Dolasetron together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideHaloperidol
Severe
How does the drug interact with Xtandi 40 mg Soft Capsule:
Co-administration of Xtandi 40 mg Soft Capsule and Haloperidol can affect the rhythm of the heart.

How to manage the interaction:
Co-administration of Xtandi 40 mg Soft Capsule and Haloperidol can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, breathing difficulty, heart palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideCobicistat
Severe
How does the drug interact with Xtandi 40 mg Soft Capsule:
When Xtandi 40 mg Soft Capsule is taken with Cobicistat, the amount of Cobicistat in the blood may be reduced. This might decrease Cobicistat's ability in treating HIV infection.

How to manage the interaction:
There may be a possibility of interaction between Xtandi 40 mg Soft Capsule and Cobicistat, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideErlotinib
Severe
How does the drug interact with Xtandi 40 mg Soft Capsule:
Taking Xtandi 40 mg Soft Capsule with Erlotinib may decrease the blood levels of Erlotinib, which may make Erlotinib less effective.

How to manage the interaction:
Although taking Xtandi 40 mg Soft Capsule and Erlotinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's Wort products during Xtandi 40 mg Soft Capsule treatment may lead to decrease in the effectiveness of Xtandi 40 mg Soft Capsule. Avoid St. John's Wort products during Xtandi 40 mg Soft Capsule treatment

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • BOSUTINIB
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  • FINGOLIMOD
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  • MOXIFLOXACIN

Habit Forming

No

Special Advise

  • Xtandi 40Mg Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Xtandi 40Mg Capsule .
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Peripheral blood counts should be frequently monitored during Xtandi 40Mg Capsule  treatment and, when appropriate, until recovery is achieved.
  • Do not donate sperm during treatment with Xtandi 40Mg Capsule for three months after your last dose.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

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