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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

LOCAL ANESTHETICS

Country of origin

India

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - XYL0003

Author Details

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FAQs

Xylocaine Adrenaline 2% Injection contains Lidocaine and Adrenaline. Lidocaine blocks the influx of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses (nerve signal). Hence, it gives an anesthetic effect and decreases the sensation of pain. Adrenaline works by constricting and narrowing blood vessels by acting on alpha receptors that cause muscle contractions. Thus, it decreasing the bleeding and the effects of Xylocaine Adrenaline 2% Injection will last longer.

You are not recommended to take duloxetine (antidepressant) with Xylocaine Adrenaline 2% Injection as co-administration of these two medicines may increase the risk of high blood pressure and heart rate. However, please consult your doctor before taking other medicines with Xylocaine Adrenaline 2% Injection.

Xylocaine Adrenaline 2% Injection causes drowsiness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

A person of age 65 or older should use Xylocaine Adrenaline 2% Injection with caution, as directed by the doctor as the chances of occurrence of side effects increase in older people.

Xylocaine Adrenaline 2% Injection should be used with caution in patients suffering from heart rhythm disorders as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have any heart problems before taking Xylocaine Adrenaline 2% Injection so that the dose may be adjusted appropriately or an alternate medicine may be prescribed.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Xylocaine Adrenaline 2% Injection. Alcohol intake, along with Xylocaine Adrenaline 2% Injection, may cause increased drowsiness.

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Pregnancy

Unsafe

It is not recommended to take Xylocaine Adrenaline 2% Injection while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe you Xylocaine Adrenaline 2% Injection only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Please consult your doctor if you have any concerns regarding this, your doctor will decide whether breastfeeding mothers can take Xylocaine Adrenaline 2% Injection or not.

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Driving

Caution

Xylocaine Adrenaline 2% Injection may cause drowsiness and vision disturbances, do not drive or operate heavy machinery if you feel drowsy.

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Liver

Caution

Xylocaine Adrenaline 2% Injection should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Xylocaine Adrenaline 2% Injection should be used with caution in patients with kidney impairment/kidney disease. Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Xylocaine Adrenaline 2% Injection should not be used by children, as the efficacy and safety have not been established.

About Xylocaine Adrenaline 2% Injection

Xylocaine Adrenaline 2% Injection belongs to the class of local anaesthetics known as numbing medication used to produce local numbness (anaesthesia) on skin before surgical procedure and reduce pain and discomfort caused by invasive medical procedures such as surgery. It is also used to reduce the discomfort of contractions during labour. Xylocaine Adrenaline 2% Injection is also used to treat certain types of chronic pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person.

Xylocaine Adrenaline 2% Injection is a combination of two drugs: Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Lidocaine works by blocking the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain. Adrenaline works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine.

Xylocaine Adrenaline 2% Injection will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side-effects such as reactions at the application site (burning, itching, redness, and irritation), nausea, vomiting and allergy. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

The usage of Xylocaine Adrenaline 2% Injection is not allowed in patients who are hypersensitive to any of the components present in it as it may cause serious side effects.  Before starting the medication, tell your doctor about your medical history, especially if you have high blood pressure or heart problems such as a slow heart beat, hypovolaemia (decreased volume of blood), epilepsy, diabetes, liver disease, a certain blood disorder (methemoglobinemia). Please consult a doctor if you are pregnant or breastfeeding before taking Xylocaine Adrenaline 2% Injection. Xylocaine Adrenaline 2% Injection is not recommended for children. 

Uses of Xylocaine Adrenaline 2% Injection

Pain relief (local anaesthesia).

Medicinal Benefits Mweb

Medicinal Benefits

Xylocaine Adrenaline 2% Injection is a combination of two medicines, namely; Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Xylocaine Adrenaline 2% Injection is used to produce local numbness (anaesthesia). Lidocaine is a local anesthetic which works by blocking the transmission of the nerve signals in the body, thereby helps in decreasing the sensation of pain. Adrenaline is a vasoconstrictor which works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine. Xylocaine Adrenaline 2% Injection is used to reduce pain and discomfort caused by invasive medical procedures such as surgery, needle punctures or insertion of a breathing tube or catheter. It is also used to reduce the discomfort of contractions during labour. Xylocaine Adrenaline 2% Injection will start to work rapidly after being injected and will slowly wear off when the surgical procedure is over.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Side Effects of Xylocaine Adrenaline 2% Injection

  • Pale skin
  • Burning sensation
  • Stinging sensation
  • Erythema (skin redness)
  • Itching
  • Pain at the site of application
  • Petechiae (red or purple spot caused by bleeding into the skin)

Drug Warnings

Do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Xylocaine Adrenaline 2% Injection if you are pregnant or breastfeeding, your doctor will prescribe you Xylocaine Adrenaline 2% Injection only if the benefits outweigh the risks. Xylocaine Adrenaline 2% Injection causes drowsiness, so drive with caution. Avoid consuming alcohol along with Xylocaine Adrenaline 2% Injection as it could lead to increased drowsiness. Xylocaine Adrenaline 2% Injection may not be suitable for people with respiratory disease, heart disease, epilepsy, low blood pressure, kidney or liver problems. Inform your doctor about your health condition and medications before taking Xylocaine Adrenaline 2% Injection to rule out any side-effects.

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Xylocaine Adrenaline 2% Injection 30 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Saquinavir can increase the blood levels of Xylocaine Adrenaline 2% Injection 30 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Dapsone with Xylocaine Adrenaline 2% Injection 30 ml can increase the risk of methemoglobinemia (a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Xylocaine Adrenaline 2% Injection 30 ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Sulfadiazine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Xylocaine Adrenaline 2% Injection 30 ml with Sulfadiazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml with phenobarbital may increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking phenobarbital and Xylocaine Adrenaline 2% Injection 30 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Nitrofurantoin may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Nitrofurantoin with Xylocaine Adrenaline 2% Injection 30 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LidocainePrilocaine
Severe
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Prilocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Prilocaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Combination of chloroquine and Xylocaine Adrenaline 2% Injection 30 ml can increase the risk of methemoglobinemia (an uncommon disease that can result in low oxygen levels in tissues and important organs).

How to manage the interaction:
Taking chloroquine and Xylocaine Adrenaline 2% Injection 30 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience any of the following symptoms: gray discoloration of the skin, abnormal blood coloring, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, rapid heartbeat, palpitations, anxiety, or confusion, consult your doctor
LidocaineAmyl nitrite
Severe
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Xylocaine Adrenaline 2% Injection 30 ml with Amyl nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Xylocaine Adrenaline 2% Injection 30 ml and Amyl nitrite, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineIohexol
Severe
How does the drug interact with Xylocaine Adrenaline 2% Injection 30 ml:
Taking Iohexol and Xylocaine Adrenaline 2% Injection 30 ml may increase the risk of causing seizures(fits).

How to manage the interaction:
Although there is a possible interaction between Xylocaine Adrenaline 2% Injection 30 ml and Iohexol, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LORAZEPAM
  • ALPRAZOLAM
  • HALOTHANE
  • PRILOCAINE
  • TRAMADOL
  • AMIODARONE
  • PROPRANOLOL
  • SODIUM NITRITE
  • DOMPERIDONE
  • CIMETIDINE
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE

Habit Forming

No

Special Advise

Inform your doctor about any blood diseases/problems like hypovolaemia (decreased volume of blood), heart problems such as a slow heart beat, difficulty breathing or ever had a stroke.

Diet & Lifestyle Advise

  • ​Indulge yourself in mindfulness activities like yoga that help in reducing stress levels and pain management.
  • Never forget to get about 7-8 hours of sleep as it will help your muscles to heal fast and reduces inflammation and swelling.
  • Take out some time for meditation, read books, take a warm bubble bath, spend time with family or listen to relaxing music.
  • Make a habit of eating food rich in antioxidants such as berries, onion, milk, spinach, kidney beans, dark chocolate, etc.
  • Foods rich in flavonoids helps the body to heal faster by reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Strictly limit smoking and alcohol consumption as it may worsen the side effects of the drug.

Xylocaine Adrenaline 2% Injection Substitute

Always consult your doctor before taking any new medications and supplements

  • El-Ligno ADR Injection 30 ml

    by Others

    0.92per tablet
  • Ignol-ADR Injection 30 ml

    by Others

    1.14per tablet

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