Zerodol-MR Tablet is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
 
Zerodol-MR Tablet contains Tizanidine (muscle relaxant) and Aceclofenac (NSAID). Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac works by blocking the effect of prostaglandins which cause pain and inflammation. Thereby, reduces mild to moderate pain and inflammation. Together, Zerodol-MR Tablet helps in relieving pain due to muscle spasms.
 
You are advised to take Zerodol-MR Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Zerodol-MR Tablet may cause drowsiness and dizziness, so drive with caution. Zerodol-MR Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Zerodol-MR Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions.

Zerodol-MR Tablet is a combination of two drugs, namely: Tizanidine and Aceclofenac. Zerodol-MR Tablet is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Tizanidine is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac is an analgesic that works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Zerodol-MR Tablet helps in relieving pain due to muscle spasms.

Do not take Zerodol-MR Tablet if you are allergic to any of its components. Inform your doctor if you have/ had high blood pressure, heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of the intestine, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Zerodol-MR Tablet may cause drowsiness and dizziness, so drive only if you are alert. Zerodol-MR Tablet is not recommended for children as safety and effectiveness have not been established. Stop taking Zerodol-MR Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.