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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Shef Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zidom-R Tablet

Zidom-R Tablet belongs to a group of medicines called gastrointestinal agents used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.

Zidom-R Tablet is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Zidom-R Tablet helps in treating acidity.

Take Zidom-R Tablet 30-60minutes prior to food. Swallow Zidom-R Tablet as a whole with a glass of water; do not chew, or break it. You are advised to take Zidom-R Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. Consult your doctor before taking Zidom-R Tablet if you are pregnant or breastfeeding. Zidom-R Tablet may cause sleepiness, so drive only if you are alert. Zidom-R Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Zidom-R Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Zidom-R Tablet

Gastro-oesophageal reflux disease, peptic ulcers and Zollinger-Ellison syndrome.

Directions for Use

Take Zidom-R Tablet 30-60minutes prior to food. Swallow Zidom-R Tablet as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Zidom-R Tablet belongs to a group of medicines called gastrointestinal agents used to treat heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Zidom-R Tablet is a combination of two drugs, namely: Omeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Zidom-R Tablet helps in treating acidity.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Zidom-R Tablet if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking Zidom-R Tablet if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. Talk to your doctor before taking Zidom-R Tablet if you have osteoporosis as Zidom-R Tablet may increase the risk of bone fractures on long-term treatment. Consult your doctor before taking Zidom-R Tablet if you are pregnant or breastfeeding. Zidom-R Tablet may cause sleepiness, so drive only if you are alert. Zidom-R Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Zidom-R Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical
How does the drug interact with Zidom-R Tablet:
Using rilpivirine together with Zidom-R Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Zidom-R Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
Zidom-R Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Zidom-R Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
When taken together Zidom-R Tablet may interfere with the absorption of gefitinib into the bloodstream and reduce its effectiveness.

How to manage the interaction:
Although taking Zidom-R Tablet with gefitinib can lead to interaction, they can be taken if recommended by a doctor. However, if you have no other treatment options, it is suggested that you take gefitinib 12 hours before or after Zidom-R Tablet to reduce the impact of the interaction. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
When Zidom-R Tablet is used with citalopram the blood levels of citalopram may increase, increasing the risk of certain adverse effects, such as an abnormal heart rhythm, which can be serious.

How to manage the interaction:
Although taking Zidom-R Tablet and citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid/pounding heartbeats while taking these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
Taking tacrolimus with Zidom-R Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking Zidom-R Tablet with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleNelfinavir
Severe
How does the drug interact with Zidom-R Tablet:
Using Zidom-R Tablet in conjunction with nelfinavir can reduce the effectiveness of nelfinavir.

How to manage the interaction:
Although taking Zidom-R Tablet with nelfinavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
Taking Zidom-R Tablet and carbamazepine may possibly reduce the effects of Zidom-R Tablet, which could reduce its capacity to treat the condition.

How to manage the interaction:
Although taking Zidom-R Tablet and carbamazepine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zidom-R Tablet:
When taken together Zidom-R Tablet can lower the levels of Clopidogrel in the blood, which can result in a decreased effectiveness of clopidogrel.

How to manage the interaction:
Taking Zidom-R Tablet and clopidogrel together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
When taken together, Zidom-R Tablet, through decreasing stomach acid, can reduce atazanavir absorption and blood levels, making the medication less effective.

How to manage the interaction:
Although taking Zidom-R Tablet with atazanavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zidom-R Tablet:
Co-administration of Zidom-R Tablet with mesalazine can decrease the effects of mesalazine.

How to manage the interaction:
There could be a possible interaction between Mesalazine and Zidom-R Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zidom-R Tablet contains Omeprazole and Domperidone. Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Zidom-R Tablet helps in treating acidity.

Diarrhoea might be a side-effect of Zidom-R Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Zidom-R Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Zidom-R Tablet contains domperidone which helps in treating nausea and vomiting. However, Zidom-R Tablet is used to treat acidity. Please consult your doctor, he/she may prescribe you an alternate medicine for treating nausea and vomiting.

Do not take Zidom-R Tablet for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Zidom-R Tablet for 14days.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CIPROFLOXACIN
  • ATORVASTATIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • ERLOTINIB
  • METHOTREXATE
  • CITALOPRAM
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • CYANOCOBALAMIN
  • PHENYTOIN
  • CISAPRIDE
  • DIGOXIN
  • TACROLIMUS
  • RIFAMPICIN

Special Advise

  • Inform your doctor before taking Zidom-R Tablet  if you are due to have Chromogranin A test.
  • Zidom-R Tablet may cause changes in a blood test to check liver functioning. Inform the person doing the tests that you are taking Zidom-R Tablet .
  • Talk to your doctor before taking Zidom-R Tablet if you have osteoporosis as Zidom-R Tablet may increase the risk of bone fractures on long-term treatment.

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion

Zollinger-Ellison syndrome: It is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.

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