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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zilsar CH 40/12.5 Tablet

Zilsar CH 40/12.5 Tablet belongs to the class of drugs called anti-hypertensive agents primarily used to treat high blood pressure (hypertension). Hypertension (high blood pressure) is a medical condition in which the blood pressure is elevated persistently in the arteries. High blood pressure is mostly caused by obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing.

Zilsar CH 40/12.5 Tablet consists of two medicines, namely: Azilsartan and Chlorthalidone. Azilsartan is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin. This helps relax the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone belongs to thiazide diuretics (water pill) which inhibits fluid retention or build-up. Thus, it relaxes the blood vessels and improves blood circulation. Together, Zilsar CH 40/12.5 Tablet helps lower raised blood pressure.

Your doctor will decide the dosage and duration based on your medical condition. In some cases, Zilsar CH 40/12.5 Tablet can cause side effects like nausea, taste changes, stomach upset, diarrhoea, headache, weakness, dizziness, and decreased blood pressure. Most of these side effects of Zilsar CH 40/12.5 Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking Zilsar CH 40/12.5 Tablet , let your doctor know if you have kidney, liver problems or severe dehydration. Avoid using Zilsar CH 40/12.5 Tablet if you are pregnant. Breastfeeding women should consult their doctor before taking Zilsar CH 40/12.5 Tablet . Do not consume alcohol with Zilsar CH 40/12.5 Tablet as it may increase the risk of side effects. Avoid driving or operating machinery if you experience dizziness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Zilsar CH 40/12.5 Tablet

Hypertension

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zilsar CH 40/12.5 Tablet is a combination of Azilsartan and Chlorthalidone. It is used to treat high blood pressure. Azilsartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Together, Zilsar CH 40/12.5 Tablet helps treat high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not stop taking Zilsar CH 40/12.5 Tablet without your doctor's advice. Sudden stopping of Zilsar CH 40/12.5 Tablet may cause changes in your blood pressure. Inform your doctor about gout, electrolyte imbalance, dehydration, heart, kidney or liver problems. Consult your doctor before using Zilsar CH 40/12.5 Tablet if you are breastfeeding. Avoid taking Zilsar CH 40/12.5 Tablet if you are pregnant. Drive or operate machinery only if you are alert, as Zilsar CH 40/12.5 Tablet may cause dizziness. Avoid alcohol consumption as it may cause unpleasant side effects. Keep your doctor informed about your health condition and medications to rule out any side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zilsar CH 40/12.5 Tablet:
Taking Aliskiren with Zilsar CH 40/12.5 Tablet can increase the risk of low blood pressure and high potassium levels in the body.

How to manage the interaction:
Taking Zilsar CH 40/12.5 Tablet with Aliskiren is generally avoided as it may lead to an interaction, it can be taken if prescribed by the doctor. Consult the doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Make sure to hydrate while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Co-administration of Zilsar CH 40/12.5 Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Zilsar CH 40/12.5 Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Taking Zilsar CH 40/12.5 Tablet with Perindopril can cause low blood pressure, kidney function impairment, or increased potassium levels.

How to manage the interaction:
Although taking Zilsar CH 40/12.5 Tablet with Perindopril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Taking Lithium with Zilsar CH 40/12.5 Tablet can increase the blood levels of Lithium.

How to manage the interaction:
Although taking Zilsar CH 40/12.5 Tablet and Lithium together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, vomiting, muscle weakness, ringing in the ears, excessive thirst, or increased urination, you should consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Coadministration of Zilsar CH 40/12.5 Tablet with Trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between Zilsar CH 40/12.5 Tablet and trimethoprim, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Coadministration of Zilsar CH 40/12.5 Tablet with Trandolapril may cause low blood pressure, kidney function impairment, and increased potassium levels.

How to manage the interaction:
Although taking Zilsar CH 40/12.5 Tablet with Trandolapril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Taking Zilsar CH 40/12.5 Tablet with Captopril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Zilsar CH 40/12.5 Tablet with Captopril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Taking Zilsar CH 40/12.5 Tablet with Quinapril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Zilsar CH 40/12.5 Tablet with Quinapril together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Taking Zilsar CH 40/12.5 Tablet with Moexipril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Zilsar CH 40/12.5 Tablet with Moexipril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms of high potassium like nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zilsar CH 40/12.5 Tablet:
Co-administration of Zilsar CH 40/12.5 Tablet with Amiloride may raise potassium levels in the blood.

How to manage the interaction:
Although taking Amiloride and Zilsar CH 40/12.5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you happen to experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular physical activity or exercise.
  • Limit sodium chloride intake (table salt) in your daily diet.
  • Avoid smoking and alcohol consumption.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress.
  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils.
  • A low salt/sodium diet and regular exercise are recommended along with Zilsar CH 40/12.5 Tablet for effective results.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Zilsar CH 40/12.5 Tablet Substitute

Substitutes safety advice

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zilsar CH 40/12.5 Tablet works by relaxing and widening the blood vessels. It also prevents fluid retention due to excess salt build-up. This helps the heart pump blood easily throughout the body, lowering blood pressure.

Zilsar CH 40/12.5 Tablet can cause high levels of potassium in the blood leading to hyperkalaemia. Hence it is not recommended to use potassium supplements along with Zilsar CH 40/12.5 Tablet . However, consult your doctor if you are already taking other medicines before starting Zilsar CH 40/12.5 Tablet .

Chlorthalidone in Zilsar CH 40/12.5 Tablet may affect blood sugar levels in people with diabetes. Hence, it is advised to regularly monitor your sugar levels while taking Zilsar CH 40/12.5 Tablet . Your doctor may adjust the dose accordingly. Please seek medical advice for more information before starting Zilsar CH 40/12.5 Tablet .

Even though your blood pressure becomes normal after using Zilsar CH 40/12.5 Tablet , it may switch back to high ranges if you stop using it. Therefore, continue taking Zilsar CH 40/12.5 Tablet for as long as your doctor has advised.

Zilsar CH 40/12.5 Tablet may cause dehydration. It is advised to drink plenty of fluids and avoid heavy exercises and sports to prevent dehydration. If you experience extreme thirst and dry mouth for a longer period, please seek medical advice.

Consult your doctor before taking Zilsar CH 40/12.5 Tablet with other medicines as Zilsar CH 40/12.5 Tablet may increase the rate of gastrointestinal transit, which may affect the absorption of other orally administered medicines taken simultaneously.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • POTASSIUM CHLORIDE
  • ASPIRIN
  • CALCIUM CARBONATE
  • MAGNESIUM HYDROXIDE

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Thiazide diuretics like Chlorthalidone may increase serum triglyceride and cholesterol levels. Hence it is advised to monitor your cholesterol levels regularly.
  • Chlorthalidone in Zilsar CH 40/12.5 Tablet may interfere with specific lab tests like parathyroid and protein-bound iodide tests; hence, inform the person doing the tests that you are taking Zilsar CH 40/12.5 Tablet .
  • Your doctor may advise you to get a regular kidney function test and blood examinations for potassium levels and other electrolytes while using Zilsar CH 40/12.5 Tablet to rule out any renal impairment.
  • Regular monitoring of blood glucose levels is advised in diabetic patients while using Zilsar CH 40/12.5 Tablet .

Disease/Condition Glossary

Hypertension: Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases and can be caused due to obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing. Blood pressure is measured in the ratio of systolic pressure to diastolic pressure. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. The ideal blood pressure range lies between 90/60 mmHg and 120/80 mmHg. It is considered high blood pressure if the blood pressure is 140/90 mmHg or greater.

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