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  1. Home
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  3. Zisavel 100 mg Capsule 7's

Written By Veda Maddala , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
Know More
COD available

Online payment accepted

Zisavel 100 mg Capsule 7's, Pack of 1 Capsule
Zisavel 100 mg Capsule 7's, Pack of 1 Capsule
rxMedicinePrescription drug

Whats That

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Composition :

ISAVUCONAZOLE-100MG

Manufacturer/Marketer :

BDR Pharmaceuticals Internationals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS

Country of origin

India

Manufacturer/Marketer address

Engineering Center 6Th Floor, 9Th Matthew Road, Opera House, Mumbai – 400 00
Other Info - ZIS0019

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Aug 20, 2024 | 1:09 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Zisavel 100 mg Capsule contains Isavuconazole that works by inhibiting the synthesis of fungal cell membranes which are essential for their survival. Thereby, Zisavel 100 mg Capsule kills or inhibits the growth of the fungus.

Mucormycosis is not contagious. Mucormycosis is a severe fungal infection of the skin or respiratory system that occurs in people with weakened immune system.

Zisavel 100 mg Capsule may cause headache as a common side effect. However, if the condition persists or worsen, please consult a doctor.

You are not recommended to take Zisavel 100 mg Capsule with ketoconazole as it may increase the levels of Zisavel 100 mg Capsule in blood and increase the risk of side effects such as diarrhoea, vomiting, nausea or liver problems. However, please consult your doctor before taking Zisavel 100 mg Capsule with other medicines.

You are not recommended to stop using Zisavel 100 mg Capsule without consulting your doctor as it may worsen the condition or cause a recurring infection. Therefore, use Zisavel 100 mg Capsule for as long as your doctor has prescribed it and if you experience any difficulty while taking Zisavel 100 mg Capsule, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zisavel 100 mg Capsule as it may increase the risk of liver damage.

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Pregnancy

Caution

Zisavel 100 mg Capsule is given to a pregnant woman if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zisavel 100 mg Capsule. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Drive only if you are alert after taking Zisavel 100 mg Capsule as it may cause drowsiness, confusion or tiredness.

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Liver

Caution

Zisavel 100 mg Capsule should be given with caution, especially if you have a history of Liver diseases/conditions.

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Kidney

Caution

Zisavel 100 mg Capsule should be given with caution, especially if you have a history of Kidney diseases/conditions.

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Children

Unsafe

Zisavel 100 mg Capsule is not recommended for children below 18 years as the safety and effectiveness were not established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5071.pdf

About Zisavel 100 mg Capsule

Zisavel 100 mg Capsule belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis. Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs when the infection spreads from lungs to kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

Zisavel 100 mg Capsule contains Isavuconazole (antifungal) that works by inhibiting the synthesis of fungal cell membranes, which are essential for their survival. Thereby, Zisavel 100 mg Capsule kills or inhibits the growth of the fungus.

Take Zisavel 100 mg Capsule as prescribed by your doctor. You are advised to take Zisavel 100 mg Capsule for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Zisavel 100 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Zisavel 100 mg Capsule or any other medicines, please tell your doctor. Zisavel 100 mg Capsule is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Zisavel 100 mg Capsule. Avoid breastfeeding while taking Zisavel 100 mg Capsule. Drive only if you are alert after taking Zisavel 100 mg Capsule as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking Zisavel 100 mg Capsule as it may increase the risk of liver damage.

Uses of Zisavel 100 mg Capsule

Invasive aspergillosis and Mucormycosis

Medicinal Benefits Mweb

Medicinal Benefits

Zisavel 100 mg Capsule contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Zisavel 100 mg Capsule kills or stops the growth of the fungus.

Directions for Use

Take Zisavel 100 mg Capsule with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Side Effects of Zisavel 100 mg Capsule

  • Headache
  • Decreased appetite
  • Drowsiness
  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Chest pain

Drug Warnings

If you are allergic to Zisavel 100 mg Capsule or any other medicines, please tell your doctor. Zisavel 100 mg Capsule is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Zisavel 100 mg Capsule. Avoid breastfeeding while taking Zisavel 100 mg Capsule. Drive only if you are alert after taking Zisavel 100 mg Capsule as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking Zisavel 100 mg Capsule as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interactions

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IsavuconazoleSaquinavir
Critical
IsavuconazoleCisapride
Critical

Drug-Drug Interactions

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IsavuconazoleSaquinavir
Critical
How does the drug interact with Zisavel 100 mg Capsule:
When Zisavel 100 mg Capsule is taken with Saquinavir, it can increase the risk of liver damage.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazoleCisapride
Critical
How does the drug interact with Zisavel 100 mg Capsule:
When Zisavel 100 mg Capsule is taken with Cisapride, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Cisapride is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
IsavuconazoleCeritinib
Critical
How does the drug interact with Zisavel 100 mg Capsule:
Taking ceritinib with Zisavel 100 mg Capsule may significantly increase the blood levels of Zisavel 100 mg Capsule.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Ceritinib is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loose stools, yellow discoloration of skin and eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazoleRitonavir
Critical
How does the drug interact with Zisavel 100 mg Capsule:
Taking Zisavel 100 mg Capsule with Ritonavir may significantly increase the blood levels of Zisavel 100 mg Capsule, which may increase the risk of side effects.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like nausea, vomiting, loose stools, light color stools or dark urine, consult a doctor. Do not discontinue any medications without consulting a doctor.
IsavuconazolePhenytoin
Critical
How does the drug interact with Zisavel 100 mg Capsule:
Co-administration of phenytoin and Zisavel 100 mg Capsule may significantly reduce the blood levels of Zisavel 100 mg Capsule, which may make Zisavel 100 mg Capsule less effective in treating your condition.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Phenytoin is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IsavuconazoleKetoconazole
Critical
How does the drug interact with Zisavel 100 mg Capsule:
Co-administration of Ketoconazole and Zisavel 100 mg Capsule can significantly increase the blood levels of Zisavel 100 mg Capsule, which may increase the risk of side effects.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
IsavuconazoleItraconazole
Critical
How does the drug interact with Zisavel 100 mg Capsule:
The blood levels and effects of Zisavel 100 mg Capsule may be significantly enhanced by taking Itraconazole along with it.

How to manage the interaction:
Co-administration of Zisavel 100 mg Capsule and Itraconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazolePhenobarbital
Critical
How does the drug interact with Zisavel 100 mg Capsule:
When Zisavel 100 mg Capsule is taken with Phenobarbital, may decrease the blood levels of Zisavel 100 mg Capsule, which may make Zisavel 100 mg Capsule less effective.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with Phenobarbital is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
IsavuconazolePosaconazole
Critical
How does the drug interact with Zisavel 100 mg Capsule:
When Zisavel 100 mg Capsule is taken with Posaconazole, it can increase the levels of Zisavel 100 mg Capsule in the blood.

How to manage the interaction:
Although there is an interaction between Zisavel 100 mg Capsule and posaconazole, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazolePrimidone
Critical
How does the drug interact with Zisavel 100 mg Capsule:
Taking Zisavel 100 mg Capsule with primidone may decrease the blood levels of Zisavel 100 mg Capsule and reduce its effectiveness.

How to manage the interaction:
Taking Zisavel 100 mg Capsule with primidone is not recommended, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ISAVUCONAZOLE-100MGGrapefruit and Grapefruit Juice

Drug-Food Interactions

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ISAVUCONAZOLE-100MGGrapefruit and Grapefruit Juice
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit and grapefruit juice during Zisavel 100 mg Capsule treatment may cause an interaction. Avoid grapefruit products during treatment with Zisavel 100 mg Capsule

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RITONAVIR
  • EFAVIRENZ
  • RIFABUTIN
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • KETOCONAZOLE
  • ETRAVIRINE

Habit Forming

No

Special Advise

Regular blood tests are recommended while taking Zisavel 100 mg Capsule to monitor liver functioning.

Diet & Lifestyle Advise

  • Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
  • Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
  • Bandage all wounds until they heal to prevent fungal infections.
  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Zisavel 100 mg Capsule Substitute

Always consult your doctor before taking any new medications and supplements

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