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  3. Zocef Syrup 30 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

CEFUROXIME-125MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTI- BACTERIALS

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ZOC0006

Author Details

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FAQs

Zocef Syrup is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

You should avoid taking Zocef Syrup with oral birth control pills, medicines that reduces gastric acidity (like antacids, omeprazole), immuno suppressing drugs (mycophenolate or mycophenolic), medicines used for reducing uric acid (probenecid), and some urinary glucose tests. Besides this, it also interacts with thyphoid and BCG vaccines.

Depending upon the severity of your medical condition your doctor may prescribe it to you daily for a specific duration. The usual dose ofZocef Syrup is 7 days (5-10 days), but depending on your current infection state your doctor may extend your dose intake for more days.

Try to stay well hydrated by drinking at least 6 glass of water or other fluid per day. Keep your underwear clean and try to use underwear made of cotton to avoid the spread of infection. Always keep your bladder empty as much possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat urinary tract infection.

After taking an antibiotic you may need to wait for up to three hours for eating or drinking any dairy products include milk as well as butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work dampen the effect of antibiotics.

If you have taken accidently over dosage of Zocef Syrup, you may have diarrhoea, nausea or vomiting. In rare cases it can also cause convulsion or seizures (fits). Try to reach out to doctor in this case.

No. Zocef Syrup treats only bacterial infection. Cough, flu or cold are usually caused due to the viruses. So, you should consult doctor for these conditions.

Yes. Zocef Syrup may interact with birth control pills and lowers its efficiency. So, you should tell your doctor if your are using any birth control pills.

No. You should complete the full course of Zocef Syrup as your doctor prescribes. After completing the full course, the Zocef Syrup will work. You must take Zocef Syrup at the right dose, times, and for the right number of days.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Zocef Syrup.

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Pregnancy

Safe if prescribed

Zocef Syrup is a pregnancy category B drug. So, Zocef Syrup can be safely taken by pregnant women if prescribed by the doctor.

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Breast Feeding

Safe if prescribed

Zocef Syrup is excreted in human milk, caution should be exercised. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

No studies on the effects on the ability to drive and use machines have been performed. However, as this medicine may cause dizziness, patients should be warned to be cautious when driving or operating machinery.

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Liver

Caution

Consult your doctor, there is no substantial research yet on the use of Zocef Syrup

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Kidney

Caution

Consult your doctor, there is no substantial research yet on the use of Zocef Syrup

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Children

Safe if prescribed

Zocef Syrup can be given safely to children provided dose has been prescribed by a child specialist. However, There is no clinical evidences of using Zocef Syrup in children under the age of 3 months.

About Zocef Syrup

Zocef Syrup belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

Zocef Syrup is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

You should take Zocef Syrup only if your doctor has prescribed you. Zocef Syrup is available in various forms, such as oral tablets, dispersible tablets, and oral suspension. Most bacterial infections get treated within one week, while some conditions might take longer. So, it would be best if you tried to complete the dose your doctor prescribed for the specific bacterial infection. During the treatment with Zocef Syrup, you may observe some mild and transient nature of common side effects like headache, dizziness,  stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). These side effects are usually in the initial phase and then resolved after some time. However, if these side effects persist, let your doctor know about them.

Overdosage of Zocef Syrup can cause brain problems (cerebral irritation with fits or convulsions attack). There is no clinical evidence of a Zocef Syrup effect on the mother or baby during pregnancy. However, one should take the Zocef Syrup with caution. Zocef Syrup is excreted in the breastmilk, so the nursing mother should cautiously take Zocef Syrup. This antibiotic may cause dizziness, so patients should be cautious while driving a motor vehicle or operating machinery. Zocef Syrup is not recommended for people allergic or hypersensitive to Zocef Syrup, penicillin, or other beta-lactam antibiotics. In the initial stage of the treatment, you might have diarrhoea and abdominal cramps due to loss of gut flora (good intestinal/gut bacteria that aids digestion). So, the doctor may prescribe you prebiotics or probiotics to increase the number of gut flora. You can drink alcoholic beverages while taking amoxicillin, as it does not interact with Zocef Syrup. Liver and kidney-affected people should take this medication with caution.

Uses of Zocef Syrup

Bacterial infections

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Medicinal Benefits

Zocef Syrup treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Zocef Syrup also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of Zocef Syrup is seven days (5-10 days). But, your doctor might prescribe you Zocef Syrup for a longer duration depending on the condition of infection. Zocef Syrup has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Zocef Syrup in doses as prescribed by your doctor with the help of a measuring cup.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the whole contents.

Side Effects of Zocef Syrup

  • Headache
  • Dizziness
  • Stomach upset
  • Overgrowth of candida (fungal skin infection)
  • Unpleasant taste in the mouth
  • Diaper rashes
  • Eosinophilia (increased disease-fighting cells/WBC) 

Drug Warnings

Special care should be taken by the people taking Zocef Syrup who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of Zocef Syrup may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping Zocef Syrup. The case of colitis (inflammatory bowel disease) has been reported using Zocef Syrup. Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking Zocef Syrup. If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of Zocef Syrup immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking Zocef Syrup for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking Zocef Syrup should be warned to be cautious when driving or operating machinery.

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Zocef Syrup 30 ml:
Co-administration of Zocef Syrup 30 ml may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Zocef Syrup 30 ml. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Zocef Syrup 30 ml:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Zocef Syrup 30 ml.

How to manage the interaction:
Although taking Zocef Syrup 30 ml and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zocef Syrup 30 ml:
Co-administration of Dalteparin and Zocef Syrup 30 ml can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Zocef Syrup 30 ml with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zocef Syrup 30 ml:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CEFUROXIME-125MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-125MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-125MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Zocef Syrup 30 ml:
Colitis: In some cases the use of Zocef Syrup 30 ml may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Zocef Syrup 30 ml should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-125MGChronic kidney disease
Moderate
How does the disease interact with Zocef Syrup 30 ml:
Renal dysfunction: Zocef Syrup 30 ml is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Zocef Syrup 30 ml as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-125MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Zocef Syrup 30 ml:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Zocef Syrup 30 ml after dialysis or an additional dosage to be administered.

How to manage the interaction:
Zocef Syrup 30 ml serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-125MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Zocef Syrup 30 ml:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Zocef Syrup 30 ml if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Zocef Syrup 30 ml should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-125MGOther diseases of liver
Moderate
How does the disease interact with Zocef Syrup 30 ml:
liver disease: With Zocef Syrup 30 ml, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-125MGOther diseases of liver
Moderate
How does the disease interact with Zocef Syrup 30 ml:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

Drug-Drug Interactions Checker List

  • OMEPRAZOLE
  • PROBENECID
  • MYCOPHENOLIC ACID

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Zocef Syrup to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Zocef Syrup.
  • Avoid intake of alcoholic beverages with Zocef Syrup as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Zocef Syrup in fighting off infections.

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