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  3. Zolecare 4 mg Injection 1's

Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS

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Whats That

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Composition :

ZOLEDRONIC ACID-4MG

Manufacturer/Marketer :

Medicare Remedies Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

BONE ENHANCERS

Country of origin

India

Manufacturer/Marketer address

Plot No. 11, G. No 2/3 Shurashree Chs, Sector 20 C, Airoli, Navi Mumbai - 400708, Thane, Maharashtra, India
Other Info - ZOL0245

Author Details

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FAQs

Zolecare 4 mg Injection contains Zoledronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cells that destroy bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.

You are not recommended to take Zolecare 4 mg Injection if you have hypocalcemia (low levels of calcium in the blood) as it may worsen the condition. However, the levels of calcium and vitamin D may be checked before starting treatment with Zolecare 4 mg Injection.

Zolecare 4 mg Injection may cause osteonecrosis (bone damage) of the jaw. Therefore, to prevent such condition, maintain good oral hygiene and have regular dental check-ups while taking Zolecare 4 mg Injection. Also, is you wear dentures, make sure they fit properly. However, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

You are not recommended to take Zolecare 4 mg Injection with gentamicin as co-administration of these two medicines may increase the risk of very low calcium levels in the blood. However, please consult a doctor before taking Zolecare 4 mg Injection with other medicines.

Zolecare 4 mg Injection may reduce calcium levels in the blood by preventing calcium reabsorption from bones to the blood. Therefore, your doctor may prescribe calcium and vitamin D supplements, and you may be advised to take them for at least 10 days after receiving Zolecare 4 mg Injection.

Zolecare 4 mg Injection may cause flu-like symptoms (chills, tiredness, muscle and joint pain) in some patients as a common side effect. However, if the symptoms persist or worsen even after 2 weeks, please consult a doctor.

Disclaimer

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Alcohol

Caution

Interaction of alcohol with Zolecare 4 mg Injection is unknown. Please consult a doctor before consuming alcohol with Zolecare 4 mg Injection.

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Pregnancy

Unsafe

Zolecare 4 mg Injection is a category D pregnancy drug and is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Zolecare 4 mg Injection is contraindicated in breastfeeding mothers. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Zolecare 4 mg Injection may cause dizziness. Therefore, avoid driving or operating machinery if you feel dizzy after taking Zolecare 4 mg Injection.

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Liver

Caution

Take Zolecare 4 mg Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zolecare 4 mg Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Zolecare 4 mg Injection if you have severe kidney problems.

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Children

Unsafe

Zolecare 4 mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About Zolecare 4 mg Injection

Zolecare 4 mg Injection belongs to the class of medicines called 'bisphosphonates' used to treat osteoporosis (weak and brittle bones) caused by menopause or long-term steroid use. Zolecare 4 mg Injection also treats Paget’s bone and high calcium levels caused by cancer. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women.  As the density of bones decreases, they weaken and are more likely to break. 

Zolecare 4 mg Injection contains Zoledronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.

A doctor or nurse will administer Zolecare 4 mg Injection. In some cases, you may experience headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, pain in the muscles, joints, or bones, swelling, or pain at the infusion site. Most of these side effects of Zolecare 4 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zolecare 4 mg Injection or any other medicines, please tell your doctor. Avoid taking Zolecare 4 mg Injection if you are pregnant or breastfeeding and consult a doctor. Zolecare 4 mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zolecare 4 mg Injection if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zolecare 4 mg Injection may cause dizziness. Zolecare 4 mg Injection may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

Uses of Zolecare 4 mg Injection

Postmenopausal osteoporosis, Paget’s disease, Hypercalcemia (high level of calcium) in cancer

Medicinal Benefits Mweb

Medicinal Benefits

Zolecare 4 mg Injection contains Zoledronic acid used to treat postmenopausal osteoporosis, Paget’s disease, and hypercalcemia of malignancy (bone cancer in which excess of calcium exits). Zolecare 4 mg Injection binds to the bone tightly and prevents calcium removal by osteoclasts (a type of bone cell that destroy bone tissue). This prevents osteoclasts from breaking down the bone, strengthening bones, and minimizing the risk of bones breaking. Also, Zolecare 4 mg Injection may reduce calcium levels in the blood by preventing calcium reabsorption from bones to the blood. Thus, it helps in treating high calcium levels in the blood caused by cancer.

Directions for Use

Zolecare 4 mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Zolecare 4 mg Injection

  • Headache
  • Fever
  • Nausea
  • Dizziness
  • Vomiting
  • Back pain
  • Diarrhoea
  • Flu-like symptoms (chills, tiredness, muscle, and joint pain)
  • Pain in the muscles, joints, or bones
  • Swelling or pain at the infusion site

Drug Warnings

If you are allergic to Zolecare 4 mg Injection or any other medicines, please tell your doctor. Avoid taking Zolecare 4 mg Injection if you are pregnant or breastfeeding and consult a doctor. Zolecare 4 mg Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zolecare 4 mg Injection if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zolecare 4 mg Injection may cause dizziness. If you are not able to take daily calcium supplements, have had sections of the intestine or some or all of the parathyroid glands in the neck surgically removed, have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Zolecare 4 mg Injection. If you are a smoker, inform your doctor before receiving Zolecare 4 mg Injection as it may increase the risk of dental problems. Zolecare 4 mg Injection may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw. You are recommended to drink at least 2 glasses of fluids before and after treatment with Zolecare 4 mg Injection as advised by your doctor to prevent dehydration. Take calcium and vitamin D supplements as prescribed by your doctor as Zolecare 4 mg Injection may reduce calcium levels in the blood.

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • GENTAMICIN
  • FUROSEMIDE

Habit Forming

No

Special Advise

  • A preventive dental check-up is required before using Zolecare 4 mg Injection as it has been reported to cause osteonecrosis of the jaw. 
  • A blood test is recommended before taking each dose of Zolecare 4 mg Injection to monitor kidney functioning. 
  • Regular intake of calcium and vitamin D may be recommended by your doctor while taking treatment with Zolecare 4 mg Injection. 
  • While using Zolecare 4 mg Injection, you may experience musculoskeletal pain, in this case, stop taking Zolecare 4 mg Injection and consult a doctor. 

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy (Chinese white cabbage), spinach, and other green leafy vegetables.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

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