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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

Daffohils Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIPSYCHOTICS

Country of origin

India

Manufacturer/Marketer address

F-109,110, Upsidc Industrial Area,Central Hope Town,Selaqui,Dehradun-248011 (U.K)
Other Info - ZOS0061

Author Details

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FAQs

Zosar Tablet contains Trifluoperazine and Trihexyphenidyl. Trifluoperazine is a typical antipsychotic which works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is used to treat and prevent side effects such as involuntary movements (shaking of hands, muscle spasms) caused by Trifluoperazine.

Dry mouth could be a side-effect of Zosar Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Antidepressants should be avoided while taking Zosar Tablet as it might increase sedative effects. Consult your doctor before taking Zosar Tablet if you are using depressants.

Zosar Tablet can cause decreased sweating which results in rising in body temperature (hyperthermia). This serious side effect is greater in hot weather so it is advisable to drink plenty of water fluids, especially in summer. However, kidney patients should consult a doctor before drinking any fluid.

Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, feel unusually suspicious or confused. Trihexyphenidyl in Zosar Tablet may cause hallucination in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Zosar Tablet , please talk to your doctor immediately.

Zosar Tablet should be avoided by dementia (decline in memory, behaviour, thinking and ability to do daily activities) patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you are suffering from dementia before taking Zosar Tablet .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol with Zosar Tablet as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Zosar Tablet is not recommended for use during pregnancy, especially in the third trimesters as it may cause adverse effects in the baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Zosar Tablet may be unsafe to use during breastfeeding. Please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Zosar Tablet may cause dizziness, double vision or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Zosar Tablet .

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Liver

Unsafe

Zosar Tablet is not recommended for patients suffering from Liver diseases/conditions. Please consult a doctor if you have any concerns regarding this.

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Kidney

Caution

Take Zosar Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Please consult your paediatrician. Your child's doctor may weigh the benefits and risks before prescribing this medicine to your child.

About Zosar Tablet

Zosar Tablet belongs to a class of drugs called 'antipsychotics' used to prevent and treat schizophrenia (a mental illness). Additionally, Zosar Tablet may be used to anxiety and depression over a short period. Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do.

Zosar Tablet combination composed of two different medicines, namely, Trifluoperazine and Trihexyphenidyl. Trifluoperazine inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thereby, Zosar Tablet helps in controlling psychotic illness, relieving depression, lightening the mood, and relieving anxiety symptoms such as fear and panic. On the other hand, Trihexyphenidyl is an anticholinergic agent that acts on the nervous system and corrects some of the chemical imbalances that cause some side effects such as shaking of hands and muscle spasms due to Trifluoperazine.

Take Zosar Tablet as prescribed by your doctor. You are advised to take Zosar Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience nausea, constipation, dryness in the mouth, sedation, weight gain, orthostatic hypotension (sudden lowering of blood pressure on standing), urinary retention, increased prolactin level in the blood, dizziness, blurred vision, and nervousness. Most of these side effects of Zosar Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zosar Tablet or any other medicines, please tell your doctor. Avoid taking Zosar Tablet if you are pregnant, especially in the third trimester, as it may cause adverse effects in the baby such as breathing problems, muscle stiffness or weakness, shaking, etc. Please consult a doctor if you are pregnant or breastfeeding. Zosar Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse reactions. Avoid consuming alcohol along with Zosar Tablet as it could lead to increased drowsiness and dizziness. Consult your doctor before giving this medicine to your child. Keep your doctor informed about your medicines and health condition and rule out any side effects. 

Uses of Zosar Tablet

Schizophrenia, Anxiety, Depression

Medicinal Benefits Mweb

Medicinal Benefits

Zosar Tablet combination composed of two different medicines, namely; Trifluoperazine and Trihexyphenidyl used to prevent and treat relapses of schizophrenia (a mental illness). Additionally, Zosar Tablet may be used to anxiety and depression over a short period. Trifluoperazine inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behavior, and emotions. Thereby, Zosar Tablet helps in controlling psychotic illness, relieving depression, lighten the mood, and relieve anxiety symptoms such as fear and panic. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms, etc.). On the other hand, Trihexyphenidyl is used to treat and prevent side effects such as involuntary movements (shaking of hands, muscle spasms) caused by Trifluoperazine. Trihexyphenidyl exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Zosar Tablet improves muscle control and reduces stiffness, thereby helps the muscles move naturally. 

Directions for Use

Swallow Zosar Tablet as a whole with water; do not crush, break or chew it.

Side Effects of Zosar Tablet

  • Nausea
  • Constipation
  • Dry mouth
  • Sedation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • Increased prolactin level in the blood
  • Dizziness
  • Abdominal Pain
  • Excessive sweating
  • Decreased blood pressure
  • Urine retention
  • Blurred vision
  • Nervousness

Drug Warnings

If you are allergic to Zosar Tablet or any other medicines, please tell your doctor. Avoid taking Zosar Tablet if you are pregnant, especially in the third trimester, as it may cause adverse effects in the baby such as breathing problems, muscle stiffness or weakness, shaking, etc. Please consult a doctor if you are pregnant or breastfeeding. Zosar Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse reactions. Do not discontinue Zosar Tablet on your own. Inform your doctor before taking Zosar Tablet if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver, or kidney problems. Talk to your doctor immediately if you experience hallucinations. Zosar Tablet may make you sweat less, making you more likely to get heatstroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. Zosar Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Zosar Tablet as it could lead to increased drowsiness and dizziness. 

Drug-Drug Interactions

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TrihexyphenidylPotassium citrate
Critical
TrihexyphenidylPotassium chloride
Critical

Drug-Drug Interactions

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TrihexyphenidylPotassium citrate
Critical
How does the drug interact with Zosar Tablet:
Co-administration of Zosar Tablet with potassium citrate may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Zosar Tablet with potassium citrate is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylPotassium chloride
Critical
How does the drug interact with Zosar Tablet:
Co-administration of Zosar Tablet with potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Zosar Tablet with potassium chloride is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
TrifluoperazineZiprasidone
Critical
How does the drug interact with Zosar Tablet:
Co-administration of Zosar Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zosar Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TrifluoperazineMetoclopramide
Critical
How does the drug interact with Zosar Tablet:
Co-administration of Metoclopramide with Zosar Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Metoclopramide with Zosar Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping., contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylTopiramate
Severe
How does the drug interact with Zosar Tablet:
Taking Zosar Tablet with topiramate can increase the risk of increase body temperature and reduced sweating.

How to manage the interaction:
Co-administration of Zosar Tablet with Topiramate can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness or lightheaded, increase body temperature contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TrihexyphenidylKetamine
Severe
How does the drug interact with Zosar Tablet:
Taking Zosar Tablet with Ketamine can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Zosar Tablet and ketamine, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrihexyphenidylAmantadine
Severe
How does the drug interact with Zosar Tablet:
Coadministration of Allopurinol with Zosar Tablet may increase side effects such as heat intolerance, dry mouth, confusion, constipation, difficulty urinating, and blurred vision especially in the elderly or those with a debilitating (physically weak) condition.

How to manage the interaction:
If you are supposed to take Allopurinol and Zosar Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications.
TrihexyphenidylEsketamine
Severe
How does the drug interact with Zosar Tablet:
Taking Zosar Tablet with esketamine can increase the risk of other side effects.

How to manage the interaction:
Although there is a interaction between Zosar Tablet and esketamine, but can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrihexyphenidylZonisamide
Severe
How does the drug interact with Zosar Tablet:
Coadministration of Zosar Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Zosar Tablet with Zonisamide together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TrifluoperazineSotalol
Severe
How does the drug interact with Zosar Tablet:
Using sotalol together with Zosar Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Zosar Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • GUANETHIDINE
  • CODEINE
  • ATROPINE
  • PROCYCLIDINE
  • PROMAZINE
  • PROCHLORPERAZINE
  • CHLORPROMAZINE
  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • LAMOTRIGINE
  • CLONAZEPAM
  • PREGABALIN
  • LEVODOPA
  • WARFARIN
  • DESFERRIOXAMINE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • QUINIDINE
  • AMIODARONE
  • SOTALOL
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Habit Forming

No

Special Advise

  • If you are going to have a special X-ray examination of the spinal cord or brain involving metrizamide (chemical), inform your doctor that you are taking Zosar Tablet .
  • Blood tests are recommended while taking Zosar Tablet to monitor blood counts and liver functioning.
  • This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate, and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Zosar Tablet Substitute

Substitutes safety advice
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    2.90per tablet
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