How does Calpol 650 Plus Tablet work?

Calpol 650 Plus Tablet works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, Calpol 650 Plus Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.

Can I take Calpol 650 Plus Tablet with warfarin?

You are not recommended to take Calpol 650 Plus Tablet with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you are supposed to use these medicines together, you are advised to contact your physician so that the dose may be adjusted appropriately to use safely.

Does Calpol 650 Plus Tablet affect laboratory tests?

Calpol 650 Plus Tablet may affect how certain tests work such as blood sugar test and uric acid test. Therefore, if you are about to undergo blood test or any laboratory tests, inform your physician or lab technician that you are taking Calpol 650 Plus Tablet .

Can i take Calpol 650 Plus Tablet with other paracetamol containing products?

You are not recommended to take Calpol 650 Plus Tablet with other paracetamol containing products as it may cause paracetamol overdose.

What happens if i take more than the recommended dose of Calpol 650 Plus Tablet ?

If you take more than suggested doses of Calpol 650 Plus Tablet , it may cause overdose and lead to serious liver damage. The symptoms of overdose include vomiting, loss of appetite, stomach pain, paleness and nausea. However, if you notice any of these symptoms while taking Calpol 650 Plus Tablet , please consult a doctor immediately.

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Calpol 650 Plus Tablet 15's

Calpol 650 Plus Tablet 15's, Pack of 15 TabletS

How Calpol 650 Plus Tablet Works :

how it works data here

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Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

What if I have taken an overdose of Calpol 650 Plus Tablet

overdose test data here

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Author Details

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:31 AM IST

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Drug-Drug Interactions Checker List

WARFARIN
CHOLESTYRAMINE
ASPIRIN
METOCLOPRAMIDE
DOMPERIDONE
CHLORAMPHENICOL
RIFAMPICIN
PROBENECID
ISONIAZID
LAMOTRIGINE
CARBAMAZEPINE
PHENYTOIN

Drug Warnings

Avoid taking Calpol 650 Plus Tablet if allergic to it. Calpol 650 Plus Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Calpol 650 Plus Tablet . Avoid alcohol consumption with Calpol 650 Plus Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Calpol 650 Plus Tablet . Avoid taking more than recommended doses as it may increase the risk of serious liver damage.

Side Effects of Calpol 650 Plus Tablet

side effect 1

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. It can be taken with or without food anytime. Do not crush, break or chew it. Oral liquid: Shake the bottle well before use. Take the suggested dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits Mweb

Medicinal Benefits

Calpol 650 Plus Tablet contains Paracetamol, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, Calpol 650 Plus Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Uses of Calpol 650 Plus Tablet

fever

About Calpol 650 Plus Tablet

Calpol 650 Plus Tablet Test Testing Gopal belongs to the group of medicines called analgesics (pain killers), and antipyretics (fever-reducing agents) used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headache, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body like prostaglandin.

Calpol 650 Plus Tablet works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, Calpol 650 Plus Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Take Calpol 650 Plus Tablet as advised by your physician. Your doctor will recommend how often you need to take Calpol 650 Plus Tablet based on your medical condition. In some cases, Calpol 650 Plus Tablet may cause side effects such as nausea, stomach pain and dark coloured urine. Most of these side effects of Calpol 650 Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking Calpol 650 Plus Tablet if allergic to it. Calpol 650 Plus Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Calpol 650 Plus Tablet . Avoid alcohol consumption with Calpol 650 Plus Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Calpol 650 Plus Tablet .a

What if I have taken an overdose of Calpol 650 Plus Tablet

overdose test data here