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Drug-Drug Interactions
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice
Drug-Drug Interactions
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Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CLINDAMYCIN-0.5MGOther bacterial intestinal infections
Severe
CLINDAMYCIN-0.5MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
Drug-Diseases Interactions
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CLINDAMYCIN-0.5MGOther bacterial intestinal infections
Severe
How does the disease interact with Klintop Gel 15 gm:
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
CLINDAMYCIN-0.5MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Klintop Gel 15 gm:
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
CLINDAMYCIN-0.5MGOther diseases of liver
Moderate
How does the disease interact with Klintop Gel 15 gm:
The liver is the primary site of Klintop Gel 15 gm metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Klintop Gel 15 gm and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Klintop Gel 15 gm therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Klintop Gel 15 gm is primarily metabolized by the liver. Therapy with Klintop Gel 15 gm should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
The liver is the primary site of Klintop Gel 15 gm metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Klintop Gel 15 gm and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Klintop Gel 15 gm therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Klintop Gel 15 gm is primarily metabolized by the liver. Therapy with Klintop Gel 15 gm should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
CLINDAMYCIN-0.5MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Klintop Gel 15 gm:
Klintop Gel 15 gm is partially removed by the kidney. Klintop Gel 15 gm should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Klintop Gel 15 gm concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Klintop Gel 15 gm should be administered cautiously in patients with severely impaired renal function. Serum Klintop Gel 15 gm concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Klintop Gel 15 gm is partially removed by the kidney. Klintop Gel 15 gm should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Klintop Gel 15 gm concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Klintop Gel 15 gm should be administered cautiously in patients with severely impaired renal function. Serum Klintop Gel 15 gm concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
CLINDAMYCIN-0.5MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Klintop Gel 15 gm:
Klintop Gel 15 gm is partially removed by the kidney. Klintop Gel 15 gm should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Klintop Gel 15 gm concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Klintop Gel 15 gm should be administered cautiously in patients with severely impaired renal function. Serum Klintop Gel 15 gm concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Klintop Gel 15 gm is partially removed by the kidney. Klintop Gel 15 gm should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Klintop Gel 15 gm concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Klintop Gel 15 gm should be administered cautiously in patients with severely impaired renal function. Serum Klintop Gel 15 gm concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
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