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Drug-Drug Interactions
FluticasoneMifepristone
Critical
FluticasoneMibefradil
Severe
Drug-Drug Interactions
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FluticasoneMifepristone
Critical
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Otrivin C Nasal Drops 10 ml with Mifepristone may make Otrivin C Nasal Drops 10 ml less effective as a therapy.
How to manage the interaction:
Taking Otrivin C Nasal Drops 10 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Co-administration of Otrivin C Nasal Drops 10 ml with Mifepristone may make Otrivin C Nasal Drops 10 ml less effective as a therapy.
How to manage the interaction:
Taking Otrivin C Nasal Drops 10 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
FluticasoneMibefradil
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Mibefradil may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
Taking Otrivin C Nasal Drops 10 ml with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Mibefradil may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
Taking Otrivin C Nasal Drops 10 ml with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneDelavirdine
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Delavirdine and Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
Co-administration of Delavirdine and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Delavirdine and Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
Co-administration of Delavirdine and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneBoceprevir
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Boceprevir with Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
Co-administration of Boceprevir and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Boceprevir with Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
Co-administration of Boceprevir and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneCobicistat
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
When Otrivin C Nasal Drops 10 ml is taken with Cobicistat, it can cause a decrease in the metabolism of Otrivin C Nasal Drops 10 ml.
How to manage the interaction:
Co-administration of Cobicistat and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
When Otrivin C Nasal Drops 10 ml is taken with Cobicistat, it can cause a decrease in the metabolism of Otrivin C Nasal Drops 10 ml.
How to manage the interaction:
Co-administration of Cobicistat and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneKetoconazole
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Ketoconazole and Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
If you are supposed to take Otrivin C Nasal Drops 10 ml and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
Co-administration of Ketoconazole and Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the bloodstream.
How to manage the interaction:
If you are supposed to take Otrivin C Nasal Drops 10 ml and Ketoconazole together, doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneClarithromycin
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Otrivin C Nasal Drops 10 ml with Clarithromycin may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the blood stream.
How to manage the interaction:
Co-administration of Clarithromycin and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Otrivin C Nasal Drops 10 ml with Clarithromycin may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the blood stream.
How to manage the interaction:
Co-administration of Clarithromycin and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneAmprenavir
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Amprenavir and Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the blood stream.
How to manage the interaction:
Co-administration of Amprenavir and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Amprenavir and Otrivin C Nasal Drops 10 ml may significantly increase the absorption of Otrivin C Nasal Drops 10 ml into the blood stream.
How to manage the interaction:
Co-administration of Amprenavir and Otrivin C Nasal Drops 10 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneRitonavir
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Otrivin C Nasal Drops 10 ml and Ritonavir may increase the blood levels of Otrivin C Nasal Drops 10 ml.
How to manage the interaction:
If you are supposed to take Otrivin C Nasal Drops 10 ml and Ritonavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as palpitations, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, contact a doctor. Do not discontinue the medication without consulting a doctor.
Co-administration of Otrivin C Nasal Drops 10 ml and Ritonavir may increase the blood levels of Otrivin C Nasal Drops 10 ml.
How to manage the interaction:
If you are supposed to take Otrivin C Nasal Drops 10 ml and Ritonavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as palpitations, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneTroleandomycin
Severe
How does the drug interact with Otrivin C Nasal Drops 10 ml:
Co-administration of Troleandomycin may significantly increase the absorption of Otrivin C Nasal Drops 10 ml and tend to increase the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Otrivin C Nasal Drops 10 ml and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Troleandomycin may significantly increase the absorption of Otrivin C Nasal Drops 10 ml and tend to increase the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Otrivin C Nasal Drops 10 ml and Troleandomycin, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, muscle weakness, feeling down, acne, thinning skin, bruises, changes in your period, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
XYLOMETAZOLINE-0.1%W/VOther diseases of liver
Moderate
XYLOMETAZOLINE-0.1%W/VCushing syndrome
Moderate
Drug-Diseases Interactions
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XYLOMETAZOLINE-0.1%W/VOther diseases of liver
Moderate
How does the disease interact with Otrivin C Nasal Drops 10 ml:
Corticosteroids are primarily eliminated by hepatic metabolism, hence liver dysfunction may cause them to accumulate. Hepatic disease patients need to be closely watched.
How to manage the interaction:
Liver disease patients using Otrivin C Nasal Drops 10 ml should be monitored closely.
Corticosteroids are primarily eliminated by hepatic metabolism, hence liver dysfunction may cause them to accumulate. Hepatic disease patients need to be closely watched.
How to manage the interaction:
Liver disease patients using Otrivin C Nasal Drops 10 ml should be monitored closely.
XYLOMETAZOLINE-0.1%W/VCushing syndrome
Moderate
How does the disease interact with Otrivin C Nasal Drops 10 ml:
Rarely, the use of nasal and inhaled corticosteroids may cause hyperadrenocorticism or worsen its symptoms. Corticosteroid side effects can be lessened by administering them locally rather than systemically, although the dangers are still present. Drugs that are applied topically or inhaled may enter the bloodstream, especially when high concentrations are utilised. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded. During inhaled or nasal corticosteroid medication, the emergence of symptoms such irregular menstruation, acneiform lesions, cataracts, and cushingoid features may signify overuse.
How to manage the interaction:
The use of inhaled and nasal corticosteroids such as Otrivin C Nasal Drops 10 ml may rarely precipitate or aggravate conditions of hyperadrenocorticism. Hence, you are advised not to use more than the recommended dosages.
Rarely, the use of nasal and inhaled corticosteroids may cause hyperadrenocorticism or worsen its symptoms. Corticosteroid side effects can be lessened by administering them locally rather than systemically, although the dangers are still present. Drugs that are applied topically or inhaled may enter the bloodstream, especially when high concentrations are utilised. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded. During inhaled or nasal corticosteroid medication, the emergence of symptoms such irregular menstruation, acneiform lesions, cataracts, and cushingoid features may signify overuse.
How to manage the interaction:
The use of inhaled and nasal corticosteroids such as Otrivin C Nasal Drops 10 ml may rarely precipitate or aggravate conditions of hyperadrenocorticism. Hence, you are advised not to use more than the recommended dosages.
XYLOMETAZOLINE-0.1%W/VGlaucoma
Moderate
How does the disease interact with Otrivin C Nasal Drops 10 ml:
In patients with ocular herpes simplex, pharmacologic doses of corticosteroids may raise the risk of corneal perforation. In such patients, corticosteroid therapy should be delivered with caution, both orally and inhalation.
How to manage the interaction:
Inhaled and nasal Otrivin C Nasal Drops 10 ml should be used with caution in patients with ocular herpes simplex (a type of viral eye infection).
In patients with ocular herpes simplex, pharmacologic doses of corticosteroids may raise the risk of corneal perforation. In such patients, corticosteroid therapy should be delivered with caution, both orally and inhalation.
How to manage the interaction:
Inhaled and nasal Otrivin C Nasal Drops 10 ml should be used with caution in patients with ocular herpes simplex (a type of viral eye infection).
XYLOMETAZOLINE-0.1%W/VOsteoporosis without pathological fracture
Moderate
How does the disease interact with Otrivin C Nasal Drops 10 ml:
Long-term inhalation of corticosteroids may cause a decline in bone density. This effect, which has mostly been documented with high dosages (>= 800 mcg/day of beclomethasone or similar for >= 1 year), appears to be dose-related. Patients getting lesser dosages have also been shown to have lower levels of total body calcium. Patients with osteoporosis should be treated with inhaled and nasal corticosteroids over the long term with caution. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded.
How to manage the interaction:
Long-term therapy with inhaled and nasal corticosteroids should be used with caution in patients with osteoporosis. It is advised not to exceed more than the recommended dosages.
Long-term inhalation of corticosteroids may cause a decline in bone density. This effect, which has mostly been documented with high dosages (>= 800 mcg/day of beclomethasone or similar for >= 1 year), appears to be dose-related. Patients getting lesser dosages have also been shown to have lower levels of total body calcium. Patients with osteoporosis should be treated with inhaled and nasal corticosteroids over the long term with caution. It is crucial that the lowest effective dosage be used and that the recommended dosages of the various products not be exceeded.
How to manage the interaction:
Long-term therapy with inhaled and nasal corticosteroids should be used with caution in patients with osteoporosis. It is advised not to exceed more than the recommended dosages.
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