Do not use P-Cool Cream if you are allergic to any of its components. Inform your doctor if you have high blood pressure, diabetes, thyroid problems, porphyria, fits, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are using prescription/nonprescription drugs or herbal products before starting P-Cool Cream.

P-Cool Cream is a combination of three drugs, namely: Calamine, phenylephrine, and lidocaine. P-Cool Cream is used to treat pain and bleeding associated with anal fissures, external or internal haemorrhoids (piles), post-haemorrhoidectomy pain (pain after operation done to remove piles), and minor degrees of proctitis (inflammation of the rectum). Calamine has antiseptic and anti-pruritic properties. Phenylephrine is a sympathomimetic agent which decreases swelling by shrinking the blood vessels in the affected area. Lidocaine is a local anaesthetic that blocks the pain signals from the nerves to the brain, thereby decreasing the pain sensation.

P-Cool Cream is a combination medicine used to treat pain and bleeding associated with anal fissures and haemorrhoids (piles). An anal fissure is a small tear in the mucosa that lines the anus. Haemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause pain, discomfort, and bleeding.
 
P-Cool Cream is a combination of three drugs, namely: Calamine (anti-pruritic), phenylephrine (sympathomimetic agent), and lidocaine (local anaesthetic). Calamine has antiseptic and anti-pruritic properties. Phenylephrine decreases swelling by shrinking the blood vessels in the affected area. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreases the sensation of pain. 
 
In some cases, you may experience certain common side-effects such as burning sensation, irritation, itching and redness at the application site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Let your doctor know if you are using prescription/nonprescription drugs and herbal products before starting P-Cool Cream. If you are known to be allergic to any of the components in P-Cool Cream, please inform your doctor. Consult your doctor before using P-Cool Cream if you are pregnant or breastfeeding. P-Cool Cream should not be used in children unless prescribed by a doctor.