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  1. Home
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  3. Pegalup Oral Solution 200 ml

Pegalup Oral Solution 200 ml, Pack of 1
Pegalup Oral Solution 200 ml, Pack of 1

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Therapeutic Class

LAXATIVES

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:43 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Drug Interactions Checker List

  • AMIKACIN
  • AMIKACIN LIPOSOME
  • KANAMYCIN
  • NEOMYCIN
  • NETILMICIN
  • PLAZOMICIN
  • STREPTOMYCIN
  • CABOTEGRAVIR
  • DOLUTEGRAVIR
  • ERDAFITINIB
  • TOBRAMYCIN

Drug-Drug Interactions

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Potassium chlorideTrihexyphenidyl
Critical
Potassium chlorideAmitriptyline
Critical

Drug-Drug Interactions

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Potassium chlorideTrihexyphenidyl
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Co-administration of trihexyphenidyl with Pegalup Oral Solution 200 ml can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking trihexyphenidyl with Pegalup Oral Solution 200 ml is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
Potassium chlorideAmitriptyline
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
The combination of Amitriptyline and Pegalup Oral Solution 200 ml may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Amitriptyline and Pegalup Oral Solution 200 ml is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
Potassium chlorideEplerenone
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Using Eplerenone together with Pegalup Oral Solution 200 ml may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Pegalup Oral Solution 200 ml with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Potassium chlorideDarifenacin
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Darifenacin with Pegalup Oral Solution 200 ml(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darifenacin with Pegalup Oral Solution 200 ml(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.
Potassium chlorideMepenzolate
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Mepenzolate and Pegalup Oral Solution 200 ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Mepenzolate with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideDoxepin
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Doxepin with Pegalup Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Doxepin with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chloridePropantheline
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Propantheline with Pegalup Oral Solution 200 ml can increase the chance of developing stomach ulcers.

How to manage the interaction:
Taking Propantheline with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideMeclizine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Meclizine and Pegalup Oral Solution 200 ml (oral form) together can increase the potassium levels in blood.

How to manage the interaction:
Taking Meclizine with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideTolterodine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Tolterodine and Pegalup Oral Solution 200 ml together can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tolterodine and Pegalup Oral Solution 200 ml, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or less desire to eat. Do not discontinue medications without consulting a doctor.
Potassium chlorideOxybutynin
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Coadministration of Oxybutynin with Pegalup Oral Solution 200 ml can increase the risk of developing stomach ulcers.

How to manage the interaction:
Taking Oxybutynin with Pegalup Oral Solution 200 ml is generally avoided as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug Warnings

Do not use this medication without a doctor's prescription to treat constipation though it is laxative medicine. It is not intended to treat constipation. It is intended to cleanse the colon (bowel) before a colonoscopy. If you are pregnant or breastfeeding, seek medical advice from your doctor before using Pegalup Oral Solution . Inform your doctor if you have gastrointestinal obstruction, bowel perforation, and gastric retention. Before taking Pegalup Oral Solution , make sure your doctor knows your medical history and other medications you are taking. This will help to rule out any potential side effects.

Side Effects of Pegalup Oral Solution

  • Abdominal pain/cramps
  • Diarrhoea
  • Abdominal discomfort

Directions for Use

Pegalup Oral Solution should be used strictly as directed by the doctor. Read the label carefully and follow the directions for use. Mix Pegalup Oral Solution with water and consume it as advised by the doctor.

Medicinal Benefits Mweb

Medicinal Benefits

Pegalup Oral Solution is a stimulant laxative used to clear the bowel before medical procedures such as colonoscopy or barium enema. It works by increasing water retention in the intestine, which causes a bowel movement. This clears the colon so that the colonoscopy can be performed easily. Pegalup Oral Solution is rich in mineral salts that replaces lost electrolytes and prevent dehydration.

Uses of Pegalup Oral Solution

Cleanse the colon (bowel) for colonoscopy and barium enema

About Pegalup Oral Solution

Pegalup Oral Solution belongs to the class of medicines called stimulant laxatives used to cleanse the colon before a colonoscopy or barium enema (an x-ray test that determines abnormalities in the colon). Colonoscopy or barium enema is a procedure that involves inserting a flexible fibre-optic device into the anus to inspect the colon for identifying the extent of various diseases present in the large intestine or colon.

Pegalup Oral Solution contains Polyethylene glycol 3350, Sodium chloride, Sodium hydrogen carbonate, and Potassium chloride. Together, these salts increase the water content in the intestine and stimulate bowel movement. Thereby, Pegalup Oral Solution  helps to cleanse the large intestine so that the colonoscopy can be performed comfortably. Pegalup Oral Solution is rich in mineral salts that replaces lost electrolytes and prevent dehydration.

Take Pegalup Oral Solution exactly as directed. Certain typical side effects, such as diarrhoea, gastrointestinal pain/cramps, and abdominal discomfort, may occur in some circumstances. Most of these side effects do not necessitate medical treatment and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Consult your doctor before taking Pegalup Oral Solution if you are pregnant or breastfeeding. Let your doctor know if you have gastrointestinal obstruction, bowel perforation, and gastric retention. Drink plenty of fluids whilst taking Pegalup Oral Solution to prevent dehydration. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:43 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Therapeutic Class

LAXATIVES
Side effects of Pegalup Oral Solution 200 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

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Side Effects

Common Side Effects
  • Stomach Pain
  • Loose/ Watery Stools
  • Vomiting
  • Nausea
  • Itching
  • Headache

If any of the above side effects continue or intensify, seek medical advice. Professional guidance may be necessary for appropriate care and treatment adjustments.

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