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Therapeutic Class

LOCAL ANESTHETICS

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Drug-Drug Interactions Checker List

  • TOCAINIDE
  • MEXILETINE

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Xylocaine 10% Spray 50 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Saquinavir can increase the blood levels of Xylocaine 10% Spray 50 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Xylocaine 10% Spray 50 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Sulfadiazine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Xylocaine 10% Spray 50 ml with Sulfadiazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Flutamide with Xylocaine 10% Spray 50 ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Xylocaine 10% Spray 50 ml and Flutamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Trimethoprim may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Trimethoprim with Xylocaine 10% Spray 50 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience, gray skin color, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with phenobarbital may increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking phenobarbital and Xylocaine 10% Spray 50 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking phenazopyridine with Xylocaine 10% Spray 50 ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Co-administration of Phenazopyridine with Xylocaine 10% Spray 50 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking isosorbide dinitrate with Xylocaine 10% Spray 50 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Xylocaine 10% Spray 50 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineAmprenavir
Severe
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Amprenavir may increase the blood levels of Xylocaine 10% Spray 50 ml, which increases severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Xylocaine 10% Spray 50 ml and Amprenavir, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Xylocaine 10% Spray 50 ml:
Taking Xylocaine 10% Spray 50 ml with Bupivacaine may cause serious side effects including methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells), brain related problems and heart problems.

How to manage the interaction:
There may be a possibility of interaction between Xylocaine 10% Spray 50 ml and Bupivacaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop pale, gray, or blue colored skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug Warnings

Do not use Xylocaine 10% Spray if you are allergic to any of its components. Avoid using Xylocaine 10% Spray on larger skin areas or for a prolonged duration. Inform your doctor if you have methemoglobinemia (abnormal methemoglobin in the blood), heart, kidney or liver problems. Consult your doctor before using Xylocaine 10% Spray if you are pregnant or breastfeeding. Xylocaine 10% Spray is not recommended for children as safety and effectiveness have not been established.

Side Effects of Xylocaine 10% Spray

  • Burning sensation
  • Itching
  • Redness
  • Irritation

Directions for Use

Topical liquid/Gel/Ointment/Jelly: Use it as advised by the doctor. Apply the prescribed dose onto the affected area.Spray: Shake the container before use. Point the nozzle towards the application site and press the button to spray. Do not puncture, incinerate, or break the container, even if it is empty.Patch: Apply the patch to the affected area. Do not handle the patch with wet hands. Avoid bathing/showering/swimming while wearing the patch.

Medicinal Benefits Mweb

Medicinal Benefits

Xylocaine 10% Spray belongs to the class of local anaesthetics used to reduce/relieve pain and discomfort associated with skin irritation, burns, scratches, insect bites, skin abrasions, or sunburn. It is also used to treat post-herpetic neuralgia (pain due to shingles-a viral infection). Xylocaine 10% Spray is also indicated for the prevention and control of pain in urethritis (inflammation of the urethra). Xylocaine 10% Spray may also be used as an adjunct for endotracheal intubation (a medical procedure involving the placement of a tube into the windpipe through the nose or mouth). Xylocaine 10% Spray contains 'lidocaine' that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Xylocaine 10% Spray produces local numbness by blocking the nerve signal in the affected area. Hence, Xylocaine 10% Spray produces an anaesthetic effect and helps decrease the sensation of pain. Xylocaine 10% Spray may also be used to treat premature ejaculation. It works by reducing the sensitivity of skin tissue and sensation when applied to the penis. Thereby prevents premature ejaculation.

Uses of Xylocaine 10% Spray

Reduce/relieve pain and discomfort (local anaesthesia), post-herpetic neuralgia, premature ejaculation, as an adjunct for endotracheal intubation.

About Xylocaine 10% Spray

Xylocaine 10% Spray belongs to the class of local anaesthetics used to reduce/relieve pain and discomfort associated with skin irritation, burns, scratches, insect bites, skin abrasions, or sunburn. It is also used to treat post-herpetic neuralgia (lasting pain after a shingles infection). Xylocaine 10% Spray may also be used to treat premature ejaculation. It is also indicated for the prevention and control of pain in urethritis (inflammation of the urethra). Xylocaine 10% Spray may also be used as an adjunct for endotracheal intubation.
 
Xylocaine 10% Spray contains 'lidocaine' that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Xylocaine 10% Spray produces local numbness by blocking the nerve signal in the affected area. Hence, Xylocaine 10% Spray produces an anaesthetic effect and helps decrease the sensation of pain. 
 
Use Xylocaine 10% Spray as advised by the doctor. In some cases, Xylocaine 10% Spray may cause application site reactions such as burning sensation, itching, redness, and irritation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before using Xylocaine 10% Spray if you are pregnant or breastfeeding. Xylocaine 10% Spray is not recommended for children as safety and effectiveness have not been established. Avoid contact of Xylocaine 10% Spray with eyes, nose, or mouth. If contact occurs, rinse with water immediately. Do not apply Xylocaine 10% Spray on the swollen skin areas or deep puncture wounds. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

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Doctor imageWe provide you with authentic, trustworthy and relevant information

Therapeutic Class

LOCAL ANESTHETICS

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