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  3. Adgef 250 Tablet 15's

Prescription drug
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

GEFITINIB-250MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

Oral

Return Policy :

Not Returnable

Therapeutic Class

[ANTINEOPLASTIC]

Country of origin

India

Manufacturer/Marketer address

Adley Formulation, Sco- 42, Sector 12, Panchkula-134112, Haryana, India
Other Info - ADG0056

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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption with Adgef 250 Tablet 15's as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty in concentrating.

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Pregnancy

Consult your doctor

Adgef 250 Tablet 15's is restricted to use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least 6 months after taking the last dose of Adgef 250 Tablet 15's.

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Breast Feeding

Consult your doctor

Adgef 250 Tablet 15's should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant.

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Driving

Safe if prescribed

It is not known if Adgef 250 Tablet 15's may affect your driving ability or not. Drive only if you are physically stable and mentally focussed. If you experience drowsiness after taking this medication, you should not drive or operate any machinery or vehicles.

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Liver

Consult your doctor

Adgef 250 Tablet 15's should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Consult your doctor

Adgef 250 Tablet 15's is safe to take by patients dealing with kidney disease as prescribed by their doctor. The doctor may adjust the dose according to the medical condition of the patient.

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Children

Safe if prescribed

Adgef 250 Tablet 15's is not recommended for children below 18 years as the safety and effectiveness were not established.

About Adgef 250 Tablet 15's

Adgef 250 Tablet 15's belongs to the group of medicine called ‘anti-cancer’, primarily indicated in lung cancer treatment. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. In this disease, cells of the lung grow uncontrollably, and if not detected at an early stage may spread to other body parts, including the brain.

Adgef 250 Tablet 15's contains 'Gefitinib' which belongs to the group of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Adgef 250 Tablet 15's as prescribed by your doctor. You are suggested to take Adgef 250 Tablet 15's as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side effects such as itching or skin rash, acne, nail problems, vomiting, diarrhea, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Adgef 250 Tablet 15's for as long as your doctor has prescribed. Do not take Adgef 250 Tablet 15's if you are pregnant or planning for pregnancy as Adgef 250 Tablet 15's causes serious birth defects. Adgef 250 Tablet 15's should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition. Avoid consuming alcohol along with Adgef 250 Tablet 15's as it could lead to increased dizziness.

Uses of Adgef 250 Tablet 15's

Non-small cell lung cancer

Medicinal Benefits Mweb

Key Benefits

Adgef 250 Tablet 15's is indicated to the patients dealing with non-small cell lung cancer. Cancer of this type tends to spread quickly in other parts of the body. Adgef 250 Tablet 15's travels through the bloodstream and effectively destroys cancerous cells of the lung and other parts of the body. Adgef 250 Tablet 15's is a ' tyrosine kinase inhibitor (TKI)', that stops the uncontrolled growth and spread of cancerous cells.  It acts by stopping the abnormal protein action that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed, it undergoes a usual process of maturity. Cancerous cells form new cells more quickly, so Adgef 250 Tablet 15's targets cancerous cells and blocks the action of Tyrosine kinase enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Adgef 250 Tablet 15's stops the production, spread and growth of cancerous cells in the body.

Directions for Use

Adgef 250 Tablet 15's can be taken without food on an empty stomach at least one or two hours before taking a meal. Swallow it as a whole with water; do not crush, break or chew it. Do not drink any liquid other than water to swallow the medicine.

Side Effects of Adgef 250 Tablet 15's

  • Acne
  • Dry skin
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Itching or skin rash

Drug Warnings

Tell your doctor if you have liver or kidney disease, vision problems, breathing problems or taking any blood thinner like warfarin. Before undergoing any surgery, it is advised to tell the medical professional who performs the procedure about all the medicines you are taking. Some persons may experience diarrhoea as a side effect of Adgef 250 Tablet 15's, so it is advised to drink a lot of water and tell your doctor in such a case. Inform your doctor if you notice any severe side effects of Adgef 250 Tablet 15's, including shortness of breath, worsening cough, and other vision problems. You need to go to regular blood tests to check if this medicine is working fine for you.  Avoid high-fibre foods, raw fruits, cereals, vegetables, and drink lots of water as Adgef 250 Tablet 15's may cause diarrhoea. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Adgef 250 Tablet:
When Adgef 250 Tablet is taken with Thioridazine it can increase the levels of Thioridazine in the body. This increases the risk or severity of side effects in the body.

How to manage the interaction:
Co-administration of Adgef 250 Tablet with Thioridazine is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms, such as sudden dizziness, lightheadedness, fainting, trouble breathing, or experiencing heart palpitations, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Adgef 250 Tablet:
Co-administration of Lansoprazole with Adgef 250 Tablet may interfere with the absorption of Adgef 250 Tablet and reduce its effectiveness.

How to manage the interaction:
Although taking Lansoprazole and Adgef 250 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. To decrease the effects of the interaction, it is advised to take Adgef 250 Tablet either 12 hours before or 12 hours after lansoprazole. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Adgef 250 Tablet:
Coadministration of Adgef 250 Tablet with Rifampicin can decrease the blood levels of Adgef 250 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Adgef 250 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Adgef 250 Tablet:
Taking Adgef 250 Tablet with esomeprazole may reduce the effectiveness of Adgef 250 Tablet.

How to manage the interaction:
Although taking Esomeprazole and Adgef 250 Tablet together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Esomeprazole. Do not stop taking any medications without consulting a doctor.
GefitinibRifapentine
Severe
How does the drug interact with Adgef 250 Tablet:
When Adgef 250 Tablet is taken with Rifapentine, it can cause the body to process Adgef 250 Tablet faster. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Adgef 250 Tablet and Rifapentine together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Adgef 250 Tablet:
Phenobarbital can drastically lower Adgef 250 Tablet levels in the blood, making the medicine less effective.

How to manage the interaction:
Although taking phenobarbital with Adgef 250 Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
GefitinibMipomersen
Severe
How does the drug interact with Adgef 250 Tablet:
Coadministration of Adgef 250 Tablet and Mipomersen can lead to or increase the risk of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Adgef 250 Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, liver damage, or bleeding contact a doctor right away. Do not stop using any medications without talking to a doctor.
GefitinibFosphenytoin
Severe
How does the drug interact with Adgef 250 Tablet:
When Adgef 250 Tablet is taken with Fosphenytoin, it can cause the body to process Adgef 250 Tablet faster. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Fosphenytoin with Adgef 250 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any unusual symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, uncontrollable eye movements, abnormal body movements, loss of coordination, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Adgef 250 Tablet:
Coadministration of Magnesium oxide with Adgef 250 Tablet impairs absorption and increases the Adgef 250 Tablet levels in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Adgef 250 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any Blistering, peeling or loosening of the skin, bloody, black, or tarry stools, eye redness or pain, heartburn, indigestion, joint or muscle pain, or abdomen pain you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Adgef 250 Tablet:
Taking Rabeprazole together with Adgef 250 Tablet results in decreased levels of Adgef 250 Tablet in your blood. This can result in a decreased effectiveness of Adgef 250 Tablet in treating the disease.

How to manage the interaction:
Although taking Rabeprazole and Adgef 250 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take Adgef 250 Tablet 12 hours before or 12 hours after rabeprazole. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SORAFENIB
  • PACLITAXEL
  • NEOMYCIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • It is suggested to avoid taking an antacid or stomach acid-reducing medicine within 6 hours after taking Adgef 250 Tablet 15's as it may make the medicine less effective if taken simultaneously. 
  • Your doctor may suggest periodic liver function test to monitor the function of the liver due to the use of Adgef 250 Tablet 15's.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles reduce fatigue, helps in weight loss, and give strength. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting helps in improving your health, mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
  • Avoid smoking and alcohol consumption.

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