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  3. Geftistar Tablet 10's

Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Whats That

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Composition :

GEFITINIB-250MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - GEF0041

FAQs

It usually takes three to six months for most types of lung cancer to double their size. It took many years for lung cancer to reach a size that could be diagnosed in X-Ray.

The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer followed by coughing.

Geftistar Tablet may affect the ability of women to have a child. Thus it is advised to tell your doctor if you have such a plan.

It is suggested to avoid taking an antacid or stomach acid-reducing medicine within 6 hours after taking Geftistar Tablet as it may make the medicine less effective if taken simultaneously.

Geftistar Tablet is safe to be taken by a diabetic person. However, take Geftistar Tablet only after asking with a doctor as they may adjust the dosing according to the patient's condition.

Geftistar Tablet is restricted to use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least 6 months after taking the last dose of Geftistar Tablet .

Geftistar Tablet should be stopped in cases where a person faces a serious side effect that affects life quality. Otherwise, it would be best if you kept taking Geftistar Tablet until your doctor asks you to stop it.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Geftistar Tablet as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty in concentrating.

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Pregnancy

Unsafe

Geftistar Tablet is restricted to use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least 6 months after taking the last dose of Geftistar Tablet .

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Breast Feeding

Unsafe

Geftistar Tablet should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant.

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Driving

Caution

It is not known if Geftistar Tablet may affect your driving ability or not. Drive only if you are physically stable and mentally focussed. If you experience drowsiness after taking this medication, you should not drive or operate any machinery or vehicles.

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Liver

Caution

Geftistar Tablet should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Caution

Geftistar Tablet is safe to take by patients dealing with kidney disease as prescribed by their doctor. The doctor may adjust the dose according to the medical condition of the patient.

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Children

Unsafe

Geftistar Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

About Geftistar Tablet

Geftistar Tablet belongs to the group of medicine called ‘anti-cancer’, primarily indicated in lung cancer treatment. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. In this disease, cells of the lung grow uncontrollably, and if not detected at an early stage may spread to other body parts, including the brain.

Geftistar Tablet contains 'Gefitinib' which belongs to the group of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Geftistar Tablet as prescribed by your doctor. You are suggested to take Geftistar Tablet as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side effects such as itching or skin rash, acne, nail problems, vomiting, diarrhea, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Geftistar Tablet for as long as your doctor has prescribed. Do not take Geftistar Tablet if you are pregnant or planning for pregnancy as Geftistar Tablet causes serious birth defects. Geftistar Tablet should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition. Avoid consuming alcohol along with Geftistar Tablet as it could lead to increased dizziness.

Uses of Geftistar Tablet

Non-small cell lung cancer

Medicinal Benefits Mweb

Medicinal Benefits

Geftistar Tablet is indicated to the patients dealing with non-small cell lung cancer. Cancer of this type tends to spread quickly in other parts of the body. Geftistar Tablet travels through the bloodstream and effectively destroys cancerous cells of the lung and other parts of the body. Geftistar Tablet is a ' tyrosine kinase inhibitor (TKI)', that stops the uncontrolled growth and spread of cancerous cells.  It acts by stopping the abnormal protein action that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed, it undergoes a usual process of maturity. Cancerous cells form new cells more quickly, so Geftistar Tablet targets cancerous cells and blocks the action of Tyrosine kinase enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Geftistar Tablet stops the production, spread and growth of cancerous cells in the body.

Directions for Use

Geftistar Tablet can be taken without food on an empty stomach at least one or two hours before taking a meal. Swallow it as a whole with water; do not crush, break or chew it. Do not drink any liquid other than water to swallow the medicine.

Side Effects of Geftistar Tablet

  • Acne
  • Dry skin
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Itching or skin rash

Drug Warnings

Tell your doctor if you have liver or kidney disease, vision problems, breathing problems or taking any blood thinner like warfarin. Before undergoing any surgery, it is advised to tell the medical professional who performs the procedure about all the medicines you are taking. Some persons may experience diarrhoea as a side effect of Geftistar Tablet , so it is advised to drink a lot of water and tell your doctor in such a case. Inform your doctor if you notice any severe side effects of Geftistar Tablet , including shortness of breath, worsening cough, and other vision problems. You need to go to regular blood tests to check if this medicine is working fine for you.  Avoid high-fibre foods, raw fruits, cereals, vegetables, and drink lots of water as Geftistar Tablet may cause diarrhoea. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Geftistar Tablet:
When Geftistar Tablet is taken with Thioridazine it can increase the levels of Thioridazine in the body. This increases the risk or severity of side effects in the body.

How to manage the interaction:
Co-administration of Geftistar Tablet with Thioridazine is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms, such as sudden dizziness, lightheadedness, fainting, trouble breathing, or experiencing heart palpitations, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Geftistar Tablet:
Coadministration of Magnesium oxide with Geftistar Tablet impairs absorption and increases the Geftistar Tablet levels in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Geftistar Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any Blistering, peeling or loosening of the skin, bloody, black, or tarry stools, eye redness or pain, heartburn, indigestion, joint or muscle pain, or abdomen pain you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Geftistar Tablet:
Famotidine can make Geftistar Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Co-administration of Famotidine with Geftistar Tablet can result in an interaction, but it can be taken if a doctor has advised it. It is advised you to take Geftistar Tablet 6 hours before or 6 hours after famotidine, to reduce the effects of the interaction. Do not stop using any medications without a doctor's advice.
How does the drug interact with Geftistar Tablet:
Coadministration of Geftistar Tablet with Ranitidine can reduce the acidity levels in the stomach and also decrease the effectiveness of Geftistar Tablet

How to manage the interaction:
Taking Geftistar Tablet with Ranitidine together can possibly result in an interaction, it can be taken if your doctor has advised it. It is recommended that Geftistar Tablet is either taken 6 hours before or 6 hours after Ranitidine to help minimize the impact of the interaction. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Geftistar Tablet:
Co-administration of Calcium carbonate may interfere with the absorption of Geftistar Tablet and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Geftistar Tablet if prescribed by the doctor. However, Geftistar Tablet and Calcium carbonate should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
GefitinibMipomersen
Severe
How does the drug interact with Geftistar Tablet:
Coadministration of Geftistar Tablet and Mipomersen can lead to or increase the risk of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Geftistar Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, liver damage, or bleeding contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Geftistar Tablet:
Taking Rabeprazole together with Geftistar Tablet results in decreased levels of Geftistar Tablet in your blood. This can result in a decreased effectiveness of Geftistar Tablet in treating the disease.

How to manage the interaction:
Although taking Rabeprazole and Geftistar Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take Geftistar Tablet 12 hours before or 12 hours after rabeprazole. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Geftistar Tablet:
Magnesium carbonate can make Geftistar Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Although there is a possible interaction between Geftistar Tablet and Magnesium carbonate, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on how well your treatment is working. Your doctor can help you find other options that won't interfere with your current medication. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Geftistar Tablet:
Taking Geftistar Tablet with Pantoprazole reduces the acidity level in the stomach and may interfere with the absorption of Geftistar Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Pantoprazole with Geftistar Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take Geftistar Tablet 12 hours before or 12 hours after pantoprazole to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
GefitinibMitotane
Severe
How does the drug interact with Geftistar Tablet:
When Geftistar Tablet is taken with Mitotane, it can cause the body to process Geftistar Tablet faster. This can reduce the levels and treatment outcomes of Geftistar Tablet.

How to manage the interaction:
There may be a possibility of interaction between Geftistar Tablet and Mitotane, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SORAFENIB
  • PACLITAXEL
  • NEOMYCIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • It is suggested to avoid taking an antacid or stomach acid-reducing medicine within 6 hours after taking Geftistar Tablet as it may make the medicine less effective if taken simultaneously. 
  • Your doctor may suggest periodic liver function test to monitor the function of the liver due to the use of Geftistar Tablet .

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles reduce fatigue, helps in weight loss, and give strength. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting helps in improving your health, mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
  • Avoid smoking and alcohol consumption.

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