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  1. Home
  2. Medicine

  3. Apritant 150 Injection 1's

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
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Apritant 150 Injection 1's, Pack of 1 Injection
rxMedicinePrescription drug

Whats That

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Composition :

FOSAPREPITANT-150MG

Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIEMETICS

Country of origin

India

Manufacturer/Marketer address

Msn Laboratories Pvt.Ltd., Msn House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, India
Other Info - APR0164

Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Aug 20, 2024 | 1:17 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Apritant 150 Injection works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Apritant 150 Injection may cause constipation as a common side effect. However, if the condition persists or worsens, please consult your doctor.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain intrauterine devices (IUDs) as they may not work properly when taken together with Apritant 150 Injection. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apritant 150 Injection and for up to 1 month after using Apritant 150 Injection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

The interaction of alcohol with Apritant 150 Injection is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Apritant 150 Injection. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Fosaprepitant is excreted in breast milk. Hence, if you are a nursing mother, discuss with your doctor about the best way to feed your baby if you receive Apritant 150 Injection.

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Driving

Caution

Apritant 150 Injection may cause dizziness or sleepiness in some people. Therefore, if you feel dizzy or sleepy after receiving Apritant 150 Injection, avoid driving or operating machinery.

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Liver

Caution

If you have liver disease, inform your doctor before receiving Apritant 150 Injection.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before receiving Apritant 150 Injection.

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Children

Caution

If you have any concerns regarding the use of Apritant 150 Injection in children, please consult a doctor.

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Keep Refrigerated. Do not freeze.

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5947.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210064s000lbl.pdf
  3. https://ec.europa.eu/health/documents/community-register/2017/20170111136630/anx_136630_en.pdf

About Apritant 150 Injection

Apritant 150 Injection belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines). Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apritant 150 Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Apritant 150 Injection will be administered by a healthcare professional; do not self-administer. In some cases, Apritant 150 Injection may cause common side effects such as headache, hiccups, tiredness, loss of appetite, indigestion, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately. 

If you are allergic to Fosaprepitant or other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Apritant 150 Injection. Drive only if you are alert after receiving Apritant 150 Injection. If you are taking other prescription or non-prescription medicines, inform your doctor before receiving Apritant 150 Injection.

Uses of Apritant 150 Injection

Chemotherapy-induced nausea and vomiting

Medicinal Benefits Mweb

Medicinal Benefits

Apritant 150 Injection contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Directions for Use

Apritant 150 Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Apritant 150 Injection

  • Headache
  • Hiccups
  • Tiredness
  • Loss of appetite
  • Indigestion
  • Constipation

Drug Warnings

If you are allergic to Fosaprepitant or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Apritant 150 Injection. Drive only if you are alert after receiving Apritant 150 Injection. If you are taking any other prescription or non-prescription medicines, inform your doctor before receiving Apritant 150 Injection. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Apritant 150 Injection to check your blood clotting.

Drug-Drug Interactions

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FosaprepitantFlibanserin
Critical
FosaprepitantLomitapide
Critical

Drug-Drug Interactions

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FosaprepitantFlibanserin
Critical
How does the drug interact with Apritant 150 Injection:
Coadministration of Apritant 150 Injection with Flibanserin can increase the levels of Flibanserin in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Apritant 150 Injection with Flibanserin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FosaprepitantLomitapide
Critical
How does the drug interact with Apritant 150 Injection:
When Apritant 150 Injection is taken with Lomitapide, it can increase the levels of Lomitapide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Apritant 150 Injection with Lomitapide together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - diarrhea, nausea, vomiting, pain, discomfort, indigestion, constipation, liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, bleeding or vomiting - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
FosaprepitantCisapride
Critical
How does the drug interact with Apritant 150 Injection:
Coadministration of Apritant 150 Injection with Cisapride can increase the levels of Cisapride in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Apritant 150 Injection with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantTerfenadine
Critical
How does the drug interact with Apritant 150 Injection:
When Apritant 150 Injection is taken with Terfenadine, it can lower the rate at which Apritant 150 Injection is broken down and increases its levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Apritant 150 Injection and Terfenadine together is generally avoided as it can show an interaction, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like Chest discomfort, Shortness of breath, Weakness, or palpitations, it's important to call your doctor right away - they can be serious heart problems. Do not discontinue any medications without consulting a doctor.
FosaprepitantPimozide
Critical
How does the drug interact with Apritant 150 Injection:
When Pimozide is taken with Apritant 150 Injection, it can increase the Pimozide levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Apritant 150 Injection with Pimozide is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantEliglustat
Critical
How does the drug interact with Apritant 150 Injection:
When Apritant 150 Injection is taken with Eliglustat, can increase Eliglustat levels in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Apritant 150 Injection and Eliglustat, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantAstemizole
Critical
How does the drug interact with Apritant 150 Injection:
Coadministration of Apritant 150 Injection with Astemizole can increase the levels of Astemizole in the body. This increases the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Apritant 150 Injection with Astemizole together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantDeflazacort
Severe
How does the drug interact with Apritant 150 Injection:
Coadministration of Apritant 150 Injection with Deflazacort can increase the levels of Deflazacort in the body.

How to manage the interaction:
Taking Apritant 150 Injection with Deflazacort together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantAcalabrutinib
Severe
How does the drug interact with Apritant 150 Injection:
Coadministration of Apritant 150 Injection with Acalabrutinib can reduce the metabolism and increase the levels of Acalabrutinib in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Apritant 150 Injection with Acalabrutinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantRanolazine
Severe
How does the drug interact with Apritant 150 Injection:
When Apritant 150 Injection is taken with Ranolazine, can increase the levels of Ranolazine in the body. This can increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosamprepitant with Ranolazine can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PIMOZIDE
  • ASTEMIZOLE
  • TERFENADINE
  • CISAPRIDE
  • TACROLIMUS
  • EVEROLIMUS
  • CYCLOSPORINE
  • SIROLIMUS
  • FENTANYL
  • ALFENTANIL
  • QUINIDINE
  • ETOPOSIDE
  • IRINOTECAN
  • IFOSFAMIDE
  • ACENOCOUMAROL
  • WARFARIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • TRIAZOLAM
  • PHENOBARBITAL
  • MIDAZOLAM
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • ITRACONAZOLE
  • NEFAZODONE
  • DILTIAZEM
  • DEXAMETHASONE
  • ALPRAZOLAM
  • TOLBUTAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Apritant 150 Injection Substitute

Substitutes safety advice

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  • Fosalon 150mg Injection

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