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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

AZACITIDINE-100MG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru €“ 140501, Punjab
Other Info - AZA0105

FAQs

Azafab 100 mg Injection works by preventing cancer cells from growing. Thereby, it helps treat cancer.

Men should avoid fathering a child whilst on treatment with Azafab 100 mg Injection. Consult the doctor if you wish to conserve your sperm before starting the treatment. Use effective contraception during the treatment with Azafab 100 mg Injection and for three months after stopping the treatment.

Azafab 100 mg Injection may cause a serious immune reaction known as differentiation syndrome. Consult the doctor immediately if you experience fever, rash, difficulty breathing, cough, decreased urine, rapid weight gain, low blood pressure, or swelling of the legs or arms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol affects Azafab 100 mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Azacitidine belongs to pregnancy category D. Azafab 100 mg Injection should not be used during pregnancy as it may harm the baby. Consult the doctor immediately if you become pregnant during treatment with Azafab 100 mg Injection.

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Breast Feeding

Unsafe

It is unknown if Azacitidine passes into breast milk. Breastfeeding is not recommended during treatment with Azafab 100 mg Injection.

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Driving

Caution

Azafab 100 mg Injection may cause dizziness and tiredness. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Azafab 100 mg Injection. This medicine should be used with caution in patients with severe pre-existing liver impairment.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Azafab 100 mg Injection. Monitoring patients with kidney impairment is advised.

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Children

Unsafe

Azafab 100 mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

About Azafab 100 mg Injection

Azafab 100 mg Injection belongs to the group of medicines called anti-metabolites used in adults with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. These conditions affect the bone marrow and could cause problems with normal blood cell production. 
 
Azafab 100 mg Injection contains Azacitidine, which works by preventing cancer cells from growing. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, Azafab 100 mg Injection may cause side effects such as nausea, vomiting, diarrhoea, constipation, weakness, headache, and injection site reactions. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Azafab 100 mg Injection if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azafab 100 mg Injection. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Azafab 100 mg Injection

Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia.

Medicinal Benefits Mweb

Medicinal Benefits

Azafab 100 mg Injection belongs to the group of medicines called anti-metabolites used to treat myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. Azafab 100 mg Injection contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

Directions for Use

Azafab 100 mg Injection will be administered by a qualified physician; do not self-administer.

Side Effects of Azafab 100 mg Injection

  • Reduced blood count (red blood count, white blood count, and platelets)
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Tiredness
  • Dizziness
  • Pneumonia
  • Injection site reaction (redness, pain or a skin reaction).

Drug Warnings

Do not use Azafab 100 mg Injection if you are allergic to any of its components, have advanced liver cancer, or are breastfeeding. Inform the doctor if you have a low number of platelets, red or white blood cells, heart condition or heart attack, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of liver failure (jaundice, abdominal bloating, shaking, drowsiness, and easy bruising), kidney failure (back pain, increased thirst, swelling of legs and feet, reduced passing of water, dizziness, rapid pulse, nausea, vomiting, reduced appetite, confusion, fatigue or restlessness), fever, pneumonia (shortness of breath or chest pain accompanied with fever), low levels of platelets (bleeding such as blood in stools due to bleeding in the stomach), or allergic reaction (rash, difficulty breathing, itching, or swelling of lips).

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azafab 100 mg Injection:
Taking Yellow fever vaccine with Azafab 100 mg Injection can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azafab 100 mg Injection and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
How does the drug interact with Azafab 100 mg Injection:
When Etanercept is used with Azafab 100 mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Azafab 100 mg Injection, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Azafab 100 mg Injection:
Coadministration of Filgrastim with Azafab 100 mg Injection can reduce the effects of Filgrastim.

How to manage the interaction:
Although there is an interaction between filgrastim and Azafab 100 mg Injection, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AzacitidineCertolizumab
Severe
How does the drug interact with Azafab 100 mg Injection:
Taking Azafab 100 mg Injection with Certolizumab may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azafab 100 mg Injection with Certolizumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azafab 100 mg Injection:
Taking Azafab 100 mg Injection with Teriflunomide can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Azafab 100 mg Injection and Teriflunomide together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azafab 100 mg Injection:
Taking Azafab 100 mg Injection with Natalizumab can raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Azafab 100 mg Injection and Natalizumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azafab 100 mg Injection:
Taking thalidomide together with Azafab 100 mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Azafab 100 mg Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azafab 100 mg Injection:
Taking baricitinib and Azafab 100 mg Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azafab 100 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Azafab 100 mg Injection:
Taking Infliximab with Azafab 100 mg Injection can increase the risk or severity of developing infection.

How to manage the interaction:
Although taking Azafab 100 mg Injection and Infliximab together can cause an interaction, it can be taken if a doctor has suggested it. If you experience symptoms like fever, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, and pain or burning during urination, it is recommended to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineGolimumab
Severe
How does the drug interact with Azafab 100 mg Injection:
Taking Azafab 100 mg Injection with Golimumab can raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azafab 100 mg Injection with Golimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Your doctor will recommend blood tests prior to treatment with Azafab 100 mg Injection and at the start of each cycle to check blood cell count, liver and kidney functioning.
  • Women must use reliable contraception during treatment and for six months after receiving the last dose.
  • Male patients are advised to use effective contraception during treatment and for three months after stopping the treatment.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Azafab 100 mg Injection.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat a balanced diet.

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