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  3. Azimbra 40 mg Injection 0.4 ml

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

ADALIMUMAB-40MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot C, Block, Bandra-Kurla Complex, Bandra (East), Mumbai 400 051, India
Other Info - AZI1134

FAQs

Azimbra 40 mg Injection 0.4 ml contains Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.

Azimbra 40 mg Injection 0.4 ml affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Azimbra 40 mg Injection 0.4 ml can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Azimbra 40 mg Injection 0.4 ml. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Azimbra 40 mg Injection 0.4 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Azimbra 40 mg Injection 0.4 ml.

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Driving

Not applicable

Azimbra 40 mg Injection 0.4 ml will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

Azimbra 40 mg Injection 0.4 ml should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Azimbra 40 mg Injection 0.4 ml should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

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Children

Caution

Azimbra 40 mg Injection 0.4 ml is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Azimbra 40 mg Injection 0.4 ml is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

About Azimbra 40 mg Injection 0.4 ml

Azimbra 40 mg Injection 0.4 ml belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Azimbra 40 mg Injection 0.4 ml consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Azimbra 40 mg Injection 0.4 ml may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Azimbra 40 mg Injection 0.4 ml is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

Azimbra 40 mg Injection 0.4 ml should be avoided if you are allergic to any of its components.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. Azimbra 40 mg Injection 0.4 ml may cause dizziness, so drive only if you are alert and focused. Azimbra 40 mg Injection 0.4 ml should not be given to children under two years of age as safety has not been established. Consult the doctor if you are pregnant or breastfeeding.

Uses of Azimbra 40 mg Injection 0.4 ml

Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease, Uveitis, Ulcerative colitis.

Medicinal Benefits Mweb

Medicinal Benefits

Azimbra 40 mg Injection 0.4 ml consists of Adalimumab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

Directions for Use

Azimbra 40 mg Injection 0.4 ml will be administered by a healthcare professional. Do not self-administer.

Side Effects of Azimbra 40 mg Injection 0.4 ml

  • Tingling or numbness
  • Shortness of breath
  • Vision problems
  • Injection site reactions
  • Headache
  • Nausea
  • Upper respiratory tract infections.
  • Chest pain

Drug Warnings

Azimbra 40 mg Injection 0.4 ml should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes as it can worsen your health condition. Do not take live vaccines while being treated with Azimbra 40 mg Injection 0.4 ml to prevent any serious consequences. Azimbra 40 mg Injection 0.4 ml is not recommended for use in children below two years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Coadministration of baricitinib and Azimbra 40 mg Injection 0.4 ml can raise your risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azimbra 40 mg Injection 0.4 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Combining Azimbra 40 mg Injection 0.4 ml with Cladribine can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Azimbra 40 mg Injection 0.4 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact a doctor right away. These symptoms include infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Taking Infliximab with Azimbra 40 mg Injection 0.4 ml can increase the risk or severity of developing an infection.

How to manage the interaction:
Taking Infliximab with Azimbra 40 mg Injection 0.4 ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Hydroxycarbamide when used with Azimbra 40 mg Injection 0.4 ml may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Azimbra 40 mg Injection 0.4 ml, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Using Azimbra 40 mg Injection 0.4 ml and lenalidomide together may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Lenalidomide with Azimbra 40 mg Injection 0.4 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
When Azimbra 40 mg Injection 0.4 ml is taken with Cyclophosphamide, may increase the risk of serious infections.

How to manage the interaction:
Although taking Cyclophosphamide and Azimbra 40 mg Injection 0.4 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Combining Azimbra 40 mg Injection 0.4 ml with Gemcitabine can increase the risk of side effects like developing serious infections.

How to manage the interaction:
Although taking Gemcitabine and Azimbra 40 mg Injection 0.4 ml together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like feeling sick, having a fever, diarrhea, a sore throat, muscle aches, weight loss, pain when you pee, or having trouble breathing it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Co-administration of Azimbra 40 mg Injection 0.4 ml with Prednisolone can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Prednisolone and Azimbra 40 mg Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Co-administration of Azimbra 40 mg Injection 0.4 ml with Betamethasone can increase the risk of infections.

How to manage the interaction:
Co-administration of Betamethasone with Azimbra 40 mg Injection 0.4 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: infection, complications, fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, losing weight, or pain/burning when you pee. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azimbra 40 mg Injection 0.4 ml:
Coadministration of Azimbra 40 mg Injection 0.4 ml with Busulfan may increase the risk of developing infections.

How to manage the interaction:
Although taking Busulfan and Azimbra 40 mg Injection 0.4 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, diarrhea, sore throat, muscle aches, or pain while urinating, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CERTOLIZUMAB
  • GOLIMUMAB
  • INFLIXIMAB
  • RITUXIMAB
  • ANAKINRA
  • ABATACEPT

Habit Forming

No

Special Advise

  • It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment, though the patient gets a negative tuberculin test.
  • It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Azimbra 40 mg Injection 0.4 ml.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

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