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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

ADALIMUMAB-40MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - MAB0028

FAQs

Mabvinra 40 mg Injection contains Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.

Mabvinra 40 mg Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Mabvinra 40 mg Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Mabvinra 40 mg Injection . Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Mabvinra 40 mg Injection . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Mabvinra 40 mg Injection .

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Driving

Not applicable

Mabvinra 40 mg Injection will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

Mabvinra 40 mg Injection should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Mabvinra 40 mg Injection should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

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Children

Caution

Mabvinra 40 mg Injection is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Mabvinra 40 mg Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

About Mabvinra 40 mg Injection

Mabvinra 40 mg Injection  belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Mabvinra 40 mg Injection consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Mabvinra 40 mg Injection may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Mabvinra 40 mg Injection is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

Mabvinra 40 mg Injection should be avoided if you are allergic to any of its components.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. Mabvinra 40 mg Injection may cause dizziness, so drive only if you are alert and focused. Mabvinra 40 mg Injection should not be given to children under two years of age as safety has not been established. Consult the doctor if you are pregnant or breastfeeding.

Uses of Mabvinra 40 mg Injection

Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease, Uveitis, Ulcerative colitis.

Medicinal Benefits Mweb

Medicinal Benefits

Mabvinra 40 mg Injection consists of Adalimumab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

Directions for Use

Mabvinra 40 mg Injection will be administered by a healthcare professional. Do not self-administer.

Side Effects of Mabvinra 40 mg Injection

  • Tingling or numbness
  • Shortness of breath
  • Vision problems
  • Injection site reactions
  • Headache
  • Nausea
  • Upper respiratory tract infections.
  • Chest pain

Drug Warnings

Mabvinra 40 mg Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes as it can worsen your health condition. Do not take live vaccines while being treated with Mabvinra 40 mg Injection to prevent any serious consequences. Mabvinra 40 mg Injection is not recommended for use in children below two years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
When Etoposide is used with Mabvinra 40 mg Injection 0.4 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etoposide and Mabvinra 40 mg Injection 0.4 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Co-administration of Mabvinra 40 mg Injection 0.4 ml and hydrocortisone together can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Mabvinra 40 mg Injection 0.4 ml and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Taking pazopanib with Mabvinra 40 mg Injection 0.4 ml may increase the risk of serious infections.

How to manage the interaction:
Although taking Pazopanib and Mabvinra 40 mg Injection 0.4 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
When Pitavastatin and Mabvinra 40 mg Injection 0.4 ml are taken together, can increase nerve damage.

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Mabvinra 40 mg Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience weakness, numbness, pain, burning, or tingling in your hands, feet, or limbs, consult the doctor.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Co-administration of Mabvinra 40 mg Injection 0.4 ml with fludrocortisone can increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between Fludrocortisone and Mabvinra 40 mg Injection 0.4 ml, it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Using Mabvinra 40 mg Injection 0.4 ml together with Dasatinib may increase the risk of infections.

How to manage the interaction:
There may be a possibility of interaction between Dasatinib and Mabvinra 40 mg Injection 0.4 ml, but it can be taken if prescribed by a doctor. If you experience fever, a sore throat, muscle pain, difficulty breathing, pain, or burning when you urinate, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Combining Mabvinra 40 mg Injection 0.4 ml with Carfilzomib can increase the risk of infections.

How to manage the interaction:
Co-administration of Carfilzomib with Mabvinra 40 mg Injection 0.4 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Combining Mabvinra 40 mg Injection 0.4 ml with Gemcitabine can increase the risk of side effects like developing serious infections.

How to manage the interaction:
Although taking Gemcitabine and Mabvinra 40 mg Injection 0.4 ml together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like feeling sick, having a fever, diarrhea, a sore throat, muscle aches, weight loss, pain when you pee, or having trouble breathing it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
When Everolimus is used with Mabvinra 40 mg Injection 0.4 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Everolimus with Mabvinra 40 mg Injection 0.4 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
When Azathioprine and Mabvinra 40 mg Injection 0.4 ml are taken together, they may raise the risk of severe infections.

How to manage the interaction:
Although there is a possible interaction between Azathioprine and Mabvinra 40 mg Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CERTOLIZUMAB
  • GOLIMUMAB
  • INFLIXIMAB
  • RITUXIMAB
  • ANAKINRA
  • ABATACEPT

Habit Forming

No

Special Advise

  • It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment, though the patient gets a negative tuberculin test.
  • It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Mabvinra 40 mg Injection .

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

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