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  3. BONSPARK NASAL SPRAY 3.7ML

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Synonym :

CALCITONIN SALMON

Composition :

CALCITONIN-200IU

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

HYPOCALCEMIC AGENTS

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - BON0082

FAQs

BONSPARK NASAL SPRAY contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness).

If you have osteoporosis, avoid smoking, or try to quit. Tobacco use disrupts the mechanisms of bone turnover, resulting in reduced bone mass and bone mineral density (BMD), making bones prone to osteoporosis.

BONSPARK NASAL SPRAY contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones become comparatively less; hence the bone damage is halted. Using BONSPARK NASAL SPRAY can increase bone formation by activation of the bone-forming cells.

Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.

Yes, BONSPARK NASAL SPRAY is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. BONSPARK NASAL SPRAY inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.

Disclaimer

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Alcohol

Caution

Consuming alcohol is not advisable; it affects how the body absorbs calcium and vitamin D, both of which are essential for good bone formation.

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Pregnancy

Not applicable

BONSPARK NASAL SPRAY is intended for postmenopausal women only. So, it is not recommended for use in pregnancy.

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Breast Feeding

Not applicable

BONSPARK NASAL SPRAY is intended for postmenopausal women only. So, it is not recommended for use in breastfeeding women.

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Driving

Not applicable

BONSPARK NASAL SPRAY does not impact your ability to drive or operate machinery.

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Liver

Caution

Limited information is available on the use of BONSPARK NASAL SPRAY in patients with liver disease. Inform your doctor before receiving the BONSPARK NASAL SPRAY if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information is available about using BONSPARK NASAL SPRAY in patients with liver disease. Inform your doctor before receiving the BONSPARK NASAL SPRAY if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Not applicable

BONSPARK NASAL SPRAY is intended for postmenopausal women only. So, it is recommended not to use it in children.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About BONSPARK NASAL SPRAY

BONSPARK NASAL SPRAY belongs to groups of medications called hypocalcemic agents, primarily indicated for the treatment of postmenopausal osteoporosis in women more than five years postmenopause when alternative therapies are unsuitable. Post-menopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period.

BONSPARK NASAL SPRAY contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus it helps to treat osteoporosis in postmenopausal women.

Use BONSPARK NASAL SPRAY as prescribed by the doctor. BONSPARK NASAL SPRAY may cause certain side effects such as hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

BONSPARK NASAL SPRAY is for intranasal use only, do not inject or take it orally. Before using BONSPARK NASAL SPRAY , inform your doctor of all your medical conditions, sensitivities, and all medications you are using. BONSPARK NASAL SPRAY is intended for post-menopausal women; therefore, BONSPARK NASAL SPRAY should not be recommended for other populations. Avoid drinking alcohol because it affects how the body absorbs calcium and vitamin D, which are essential for good bone formation.

Uses of BONSPARK NASAL SPRAY

Postmenopausal osteoporosis

Medicinal Benefits Mweb

Medicinal Benefits

BONSPARK NASAL SPRAY contains Calcitonin, a calcitonin receptor agonist that prevents the loss of bones that happens after menopause and helps to rebuild bones. Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the parathyroid hormone's action, helping regulate the blood’s calcium and phosphate levels. BONSPARK NASAL SPRAY works by suppressing the activity of the osteoclasts (cells that break down bone). When the osteoclasts break down bone tissue, the calcium enters the bloodstream. BONSPARK NASAL SPRAY lessens the amount of calcium in the blood by preventing the breakdown of bone. Thereby, BONSPARK NASAL SPRAY strengthens the bones and minimizes the risk of fractures. BONSPARK NASAL SPRAY also seems to decrease the amount of calcium the kidneys can re-absorb, lowering calcium levels further.

Directions for Use

Insert the tip of the bottle into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Side Effects of BONSPARK NASAL SPRAY

  • Rhinitis (stuffy nose)
  • Epistaxis (nose bleeds)
  • Application site reactions
  • Back pain
  • Arthralgia (joint pain)
  • Headache

Drug Warnings

Before using BONSPARK NASAL SPRAY , Inform your doctor about all your medical conditions, sensitivities, and all medications you are using. BONSPARK NASAL SPRAY is intended for post-menopausal women; therefore, BONSPARK NASAL SPRAY should not be recommended for other populations. In rare situations, individuals using BONSPARK NASAL SPRAY may be affected with anaphylactic shock (a sudden, severe, life-threatening allergic reaction leading to difficulty breathing); if you encounter it, stop using BONSPARK NASAL SPRAY and contact your doctor immediately.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Bonspark Nasal Spray 3.7ml:
Etelcalcetide may decrease the calcium levels in the blood. Concomitant use with calcitonin may increase the risk of hypocalcemia, or low blood calcium.

How to manage the interaction:
Although there is an interaction, calcitonin can be taken with etelcalcetide if prescribed by the doctor. Consult the prescriber if you notice symptoms of hypocalcemia like numbness or tingling around your mouth, muscle spasms, or mental changes (irritability, depression, psychosis). Do not discontinue using any medication without contacting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CALCITONIN-200IUDisorders of mineral metabolism
Moderate
CALCITONIN-200IUDisorders of mineral metabolism
Moderate

Drug-Diseases Interactions

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CALCITONIN-200IUDisorders of mineral metabolism
Moderate
How does the disease interact with Bonspark Nasal Spray 3.7ml:
Calcium levels in the serum are reduced . Patients who already have hypocalcemia should use caution when administering calcium to prevent unwanted side effects. It is preferable to address hypocalcemia before beginning medication. A sufficient intake of calcium and vitamin D should be made sure during the course of treatment if calcitonin is used to promote bone mineral density, as in the case of osteoporosis

How to manage the interaction:
Calcitonin may cause hypocalcemic effects. Therefore, it should be administered cautiously to patients with preexisting hypocalcemia, since they may be particularly sensitive to these effects.
CALCITONIN-200IUDisorders of mineral metabolism
Moderate
How does the disease interact with Bonspark Nasal Spray 3.7ml:
Prior to beginning medication, hypocalcemia and other abnormalities of mineral metabolism, such as vitamin D deficiency, should be corrected when calcitonin is used to treat osteoporosis. The body must have an adequate quantity of calcium and vitamin D for the necessary increase in bone mineral density to occur. When treating patients with these conditions with calcitonin salmon nasal spray, serum calcium and hypocalcemia symptoms should be kept under close observation. Throughout the course of treatment, it is important to ensure an adequate intake of calcium and vitamin D

How to manage the interaction:
In patients with mineral metabolism disorders, serum calcium and symptoms of hypocalcemia should be monitored during therapy. Appropriate intake of calcium and vitamin D should be ensured throughout the course of treatment.

Drug-Drug Interactions Checker List

  • LITHIUM
  • ETELCALCETIDE
  • FOSCARNET

Habit Forming

No

Special Advise

  • Hypocalcemia has been reported. Make sure you get enough calcium and vitamin D, as recommended by the doctor.
  • Nasal side effects, including severe ulceration, are possible. Nasal examinations should be done regularly.

Diet & Lifestyle Advise

  • Consume calcium-rich foods like milk, yoghurt, cheese, green leafy vegetables, fish with bones such as salmon, sardines, calcium-fortified cereals and orange juice.
  • Exposure to sunlight helps synthesise vitamin D, essential for strong bones and muscles.
  • Eating vitamin-D-rich foods such as egg yolks, salmon, oily fish like sardines, and mackerel.
  • Indulging in regular exercise to prevent bone loss. Activities include brisk walking, dancing, jogging, and strength training exercises like lifting weights and using weight machines or elastic bands.
  • Engaging in activities for stress relief, such as meditation and yoga.
  • Preserving a healthy weight eases pressure on the bones.
  • Taking medications if one is at risk for osteoporosis.
  • Quitting smoking and limiting alcohol consumption.

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