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Prescription drug
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

INDIA

Manufacturer/Marketer address

Biochem Pharma, Lg 113 / A, Xth Central Mall, Mahavir Nagar, 90Ft Road, Next To D Mart, Kandivali - West, Mumbai - 400067.
Other Info - CYC0025

Author Details

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FAQs

Cycloxan Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloxan Tablet helps to treat cancer by killing the cancer cells.

Do not stop taking Cycloxan Tablet on your own. You are advised to take Cycloxan Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Cycloxan Tablet .

Cycloxan Tablet might interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm) and could impair fertility. Before starting treatment with Cycloxan Tablet , talk to your doctor regarding cryopreservation/freezing of eggs/sperm if you consider becoming parents.

Cycloxan Tablet might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding, or bruising or if the wounds do not heal properly.

No, it is not safe to father a child while taking Cycloxan Tablet . Use effective contraception while taking Cycloxan Tablet and for at least four months after treatment. Women of childbearing age taking Cycloxan Tablet should use highly effective contraceptives while taking Cycloxan Tablet up to 1 year after the treatment.

Disclaimer

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Alcohol

Consult your doctor

It is not known if alcohol affects Cycloxan Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Cyclophosphamide belongs to pregnancy category D. Cycloxan Tablet should not be taken during pregnancy as it might cause fetal harm. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnant.

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Breast Feeding

Unsafe

Cycloxan Tablet passes into breastmilk. Avoid breastfeeding while taking Cycloxan Tablet .

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Driving

Caution

Cycloxan Tablet may cause dizziness. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Cycloxan Tablet should be used with caution in patients with renal impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Cycloxan Tablet should be given to children only if prescribed by a doctor.

About Cycloxan Tablet

Cycloxan Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia,  nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Cycloxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Cycloxan Tablet contains ‘Cyclophosphamide’, an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloxan Tablet helps to treat cancer by killing the cancer cells.
 
You are advised to take Cycloxan Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.
 
Do not take Cycloxan Tablet if you are allergic to any of its components; or if you have bladder obstruction or other urination problems. Avoid taking Cycloxan Tablet if you are pregnant or breastfeeding. Cycloxan Tablet may cause dizziness, so drive only if you are alert. Cycloxan Tablet should be given to children only if prescribed by the doctor. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Cycloxan Tablet

Cancer, nephrotic syndrome (kidney disease)

Medicinal Benefits Mweb

Medicinal Benefits

Cycloxan Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma(cancer of plasma cells), Burkitt’s lymphoma, leukaemia (blood cancer), neuroblastoma (nerve tissue cancer), retinoblastoma (eye cancer), adenocarcinoma of the ovary (ovarian cancer), mycosis fungoides (T-cell lymphoma), rhabdomyosarcoma (soft tissue cancer), osteosarcoma (bone cancer), and breast carcinoma. Additionally, Cycloxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in pediatric patients. Cycloxan Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloxan Tablet helps to treat cancer by killing the cancer cells.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Oral liquid: Check the label for directions before use and take the prescribed dose using the dosing syringe or medicine spoon.

Side Effects of Cycloxan Tablet

  • Fever
  • Nausea
  • Vomiting
  • Diarrhoea
  • Hair loss
  • Low blood cell count
  • Abdominal pain

Drug Warnings

Do not take Cycloxan Tablet if you are allergic to any of its contents; or have urinary flow obstruction, bone marrow suppression, or infections. Talk to your doctor if you have myelosuppression, immunosuppression, infections, diabetes, heart, lung, liver, or kidney problems. Inform your doctor if you are receiving any radiotherapy or chemotherapy. Avoid taking Cycloxan Tablet if you are pregnant or breastfeeding. Cycloxan Tablet may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cycloxan Tablet:
Co-administration of Cycloxan Tablet and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Cycloxan Tablet:
Co-administration of Nalidixic acid with Cycloxan Tablet may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Cycloxan Tablet and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cycloxan Tablet:
Co-administration of Tenofovir alafenamide may cause kidney problems, and combining it with Cycloxan Tablet may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Cycloxan Tablet can be taken with Tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
How does the drug interact with Cycloxan Tablet:
Co-administration of Cycloxan Tablet and Deferiprone may increase the risk of serious and potential infections.

How to manage the interaction:
Co-administration of Cycloxan Tablet with Deferiprone can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cycloxan Tablet:
Taking Cycloxan Tablet with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Cycloxan Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideCertolizumab
Severe
How does the drug interact with Cycloxan Tablet:
When Cycloxan Tablet is taken with Certolizumab, may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between Cycloxan Tablet and Certolizumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cycloxan Tablet:
Taking Fingolimod's ability to suppress the immune system may be enhanced by Cycloxan Tablet.

How to manage the interaction:
Although taking Cycloxan Tablet and Fingolimod together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away - a serious infection, problems, high body temperature, feeling cold, loose stools, a painful throat, body discomfort, difficulty breathing, losing weight, or experiencing pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cycloxan Tablet:
The combined use of Cladribine with Cycloxan Tablet can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Cladribine with Cycloxan Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cycloxan Tablet:
Co-administration of Cycloxan Tablet with Levobupivacaine can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levobupivacaine with Cycloxan Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cycloxan Tablet:
Co-administration of Cycloxan Tablet with Teriflunomide can increase the risk of side effects.

How to manage the interaction:
Although taking Cycloxan Tablet and Teriflunomide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like fever, chills, sore throat, or muscle aches, it's best to contact a doctor right away. Other symptoms to watch out for include diarrhea, shortness of breath, weight loss, or pain during urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CYCLOPHOSPHAMIDE-50MGOther diseases of blood and blood-forming organs
Severe
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe

Drug-Diseases Interactions

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CYCLOPHOSPHAMIDE-50MGOther diseases of blood and blood-forming organs
Severe
How does the disease interact with Cycloxan Tablet:
Cycloxan Tablet usage can result in severe immunosuppression, bone marrow failure, myelosuppression (leukopenia, neutropenia, thrombocytopenia, and anaemia), and myelosuppression, which can all lead to serious and occasionally deadly infections including sepsis and septic shock. During Cycloxan Tablet treatment, complete blood counts must be closely monitored in order to determine whether the dose has to be changed. Patients should not be given Cycloxan Tablet if their neutrophil and platelet counts are below 1,500/mm3 and 50,000/mm3, respectively.

How to manage the interaction:
Close monitoring of complete blood count is advised during treatment with Cycloxan Tablet. Inform the doctor if you notice any signs or symptoms of bone marrow suppression such as fever, sore throat, local infection, or bleeding.
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe
How does the disease interact with Cycloxan Tablet:
Cycloxan Tablet should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Cycloxan Tablet treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Cycloxan Tablet should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe
How does the disease interact with Cycloxan Tablet:
Cycloxan Tablet should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Cycloxan Tablet treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Cycloxan Tablet should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe
How does the disease interact with Cycloxan Tablet:
Cycloxan Tablet should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Cycloxan Tablet treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Cycloxan Tablet should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.

Drug-Drug Interactions Checker List

  • DOXORUBICIN
  • PACLITAXEL
  • APREPITANT
  • ONDANSETRON
  • ZIDOVUDINE

Habit Forming

No

Special Advise

  • Monitoring of complete blood count while taking Cycloxan Tablet is advised.
  • Drink plenty of fluids to prevent urinary problems.
  • If you are due to have any surgery, inform the doctor that you are taking Cycloxan Tablet .

Diet & Lifestyle Advise

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Stay protected from the sun. Avoid tanning beds and cover up with clothing, sunscreen, and sunglasses.

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