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Written By aquibnaseer ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

DEFLAZACORT-1MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Country of origin

INDIA

Manufacturer/Marketer address

7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA
Other Info - DEF0027

Author Details

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FAQs

Not recommended in mild allergies. Defza 1 mg Tablet is recommended only on consulting a doctor as Defza 1 mg Tablet is a strong medicine that produces considerable side effects & thus used only in moderate to severe cases.

It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.

It is not recommended to be taken Defza 1 mg Tablet with alcohol as it may cause stomach bleeding.

No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Defza 1 mg Tablet may be used in extreme cases of seasonal allergy.

You should not use Defza 1 mg Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Defza 1 mg Tablet if you have a compromised immune system, eye problems or weak bones.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

The effect of taking both alcohol and Defza 1 mg Tablet may lead to bleeding & ulcers in the stomach. Doctors' consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Defza 1 mg Tablet crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Defza 1 mg Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Defza 1 mg Tablet.

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Kidney

Caution

Before using Defza 1 mg Tablet by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Defza 1 mg Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Defza 1 mg Tablet.

About Defza 1 mg Tablet

Defza 1 mg Tablet belongs to the class of medication called steroid primarily used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy, psoriasis & arthritis, etc.

Defza 1 mg Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the switches (receptors) that lead to their abnormal functioning or damaging effects. After taking the drug Defza 1 mg Tablet binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defza 1 mg Tablet class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defza 1 mg Tablet make organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Defza 1 mg Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Defza 1 mg Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defza 1 mg Tablet can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Defza 1 mg Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defza 1 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Defza 1 mg Tablet, please inform your doctor that you are allergic (hypersensitive) to Defza 1 mg Tablet. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Defza 1 mg Tablet is not safe to use during pregnancy. 

Uses of Defza 1 mg Tablet

Duchenne muscular dystrophy (DMD) 

Medicinal Benefits Mweb

Medicinal Benefits

Defza 1 mg Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defza 1 mg Tablet is a steroid that interacts with overactive immune cells and slows their activity and decreases the damaging effects they cause in the body. 

Directions for Use

Tablet: Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.Suspension: Measure the suspension in the measuring cup provided with the pack and consume it in the doses as directed by your doctor.

Side Effects of Defza 1 mg Tablet

Most of the side effects of Defza 1 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defza 1 mg Tablet.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defza 1 mg Tablet. Before taking Defza 1 mg Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Defza 1 mg Tablet:
Co-administration of Defza 1 mg Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
How does the drug interact with Defza 1 mg Tablet:
Using Deferasirox together with Defza 1 mg Tablet may increase the risk of gastric and intestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Deferasirox with Defza 1 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like stomach pain, dizziness, loss of appetite, nausea, vomiting, or black or tarry stools, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
DeflazacortTelaprevir
Severe
How does the drug interact with Defza 1 mg Tablet:
Coadministration of Telaprevir with Defza 1 mg Tablet can increase the levels of Defza 1 mg Tablet in the body.

How to manage the interaction:
Taking Telaprevir with Defza 1 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Defza 1 mg Tablet:
Coadministration of Fosaprepitant with Defza 1 mg Tablet can increase the levels of Defza 1 mg Tablet in the body.

How to manage the interaction:
Taking Fosaprepitant with Defza 1 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Defza 1 mg Tablet:
Coadministration of Ritonavir with Defza 1 mg Tablet can increase the levels of Defza 1 mg Tablet in the body.

How to manage the interaction:
Taking Ritonavir with Defza 1 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, mood swings, acne, stretch marks, easy bruising, cataracts, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Defza 1 mg Tablet:
Co-administration of Defza 1 mg Tablet with Cladribine may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Defza 1 mg Tablet and Cladribine, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortFosphenytoin
Severe
How does the drug interact with Defza 1 mg Tablet:
Taking Fosphenytoin with Defza 1 mg Tablet may significantly reduce the blood levels of Defza 1 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Fosphenytoin and Defza 1 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortCertolizumab
Severe
How does the drug interact with Defza 1 mg Tablet:
Co-administration of Defza 1 mg Tablet with Certolizumab may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Defza 1 mg Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Defza 1 mg Tablet:
Sparfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Defza 1 mg Tablet.

How to manage the interaction:
Although there is an interaction, Sparfloxacin can be taken with Defza 1 mg Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortBoceprevir
Severe
How does the drug interact with Defza 1 mg Tablet:
Coadministration of Boceprevir with Defza 1 mg Tablet can increase the levels of Defza 1 mg Tablet in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Boceprevir with Defza 1 mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, chest pain, or tightness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Defza 1 mg Tablet therapy may elevate Defza 1 mg Tablet levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • RIFABUTIN
  • CARBAMAZEPINE
  • PHENOBARBITONE
  • PHENYTOIN
  • PRIMIDONE

Habit Forming

No

Special Advise

  • While taking Defza 1 mg Tablet and for at least 4-6 weeks before you start taking it. If you are taking Defza 1 mg Tablet, so do not receive a 'live' vaccine or you could develop a serious infection.  
  • Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Defza 1 mg Tablet.
  • Regular eye check-ups, bone mineral test and liver function test is suggested while using Defza 1 mg Tablet. 

Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Defza 1 mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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