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DEXAMETHASONE+OFLOXACIN

About

DEXAMETHASONE+OFLOXACIN is a combination of 'corticosteroid and antibiotic', primarily used to treat bacterial eye infections. Bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids).

DEXAMETHASONE+OFLOXACIN contains Dexamethasone and Ofloxacin. Dexamethasone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen, and itchy. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for the replication, transcription, and repair of the DNA. 

Use DEXAMETHASONE+OFLOXACIN in the dose and duration prescribed by your doctor based on your medical condition. DEXAMETHASONE+OFLOXACIN is generally safe to use. However, some may experience side effects like eye discomfort, eye irritation, burning/stinging sensation, dryness, redness, and itching. Most of these side effects of DEXAMETHASONE+OFLOXACIN do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

If you are allergic to DEXAMETHASONE+OFLOXACIN or any other medicines, please tell your doctor. Inform your doctor if you have any liver or kidney diseases, fungal infections, or heart problems before using DEXAMETHASONE+OFLOXACIN. Pregnant and breastfeeding women should use DEXAMETHASONE+OFLOXACIN with proper consultation and caution. Drive or operate machinery only when you do not experience any discomfort in the eyes after the usage of eye drops.

Uses of DEXAMETHASONE+OFLOXACIN

Bacterial eye infections.

Medicinal Benefits

DEXAMETHASONE+OFLOXACIN contains Dexamethasone and Ofloxacin. Dexamethasone is a corticosteroid and blocks prostaglandins' production (chemical messengers) that make the affected area red, swollen and itchy. Ofloxacin is a quinolone antibiotic that inhibits bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Thus DEXAMETHASONE+OFLOXACIN treats bacterial eye infections.

Directions for Use

Tilt your head back and pull your lower eyelid downwards and outwards. Gently squeeze the dropper and put the eye drops inside the eye/eyes. Blink a few times to spread the medication inside your eye. It is advisable to press gently on the eyelid's inner corner for 3 minutes to prevent the solution from draining into the nose and throat, especially in children. If you are using more than one drop, it is advised to wait for about 5 minutes between drops.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DEXAMETHASONE+OFLOXACIN

  • Eye discomfort
  • Eye irritation
  • Burning/stinging sensation
  • Dryness
  • Redness
  • Itching

In-Depth Precautions and Warning

Drug Warnings

Brief your medical history to the doctor if you are allergic to DEXAMETHASONE+OFLOXACIN or any of its components. Please let your doctor know if you have a history of liver or kidney diseases, heart problems, glaucoma, cataracts, recent eye surgery, viral diseases of the conjunctiva and cornea, severe nearsightedness, diabetes, or fungal infections of the eye. Please consult your doctor if you are pregnant, planning pregnancy or breastfeeding before using DEXAMETHASONE+OFLOXACIN. Avoid driving or operating machines since the administration of DEXAMETHASONE+OFLOXACIN cause blurred vision for a while after using. DEXAMETHASONE+OFLOXACIN should be used for children only when advised by a doctor.

Drug Interactions

Drug-Drug Interaction: DEXAMETHASONE+OFLOXACIN may interact with fits medicine (phenytoin, phenobarbitone), respiratory medicines (ephedrine), antibiotics (rifampicin), and HIV/AIDS drugs (ritonavir, cobicistat)

Drug-Food Interaction: It is advised to limit alcohol intake while using DEXAMETHASONE+OFLOXACIN.

Drug-Disease Interaction: DEXAMETHASONE+OFLOXACIN is contraindicated in epithelial keratitis (foreign body sensation in the eye), viral diseases of the conjunctiva and cornea (parts of the eye), mycobacterial infection, and fungal infections of the eye.

Drug-Drug Interactions Checker List:

  • PHENYTOIN
  • PHENOBARBITONE
  • EPHEDRINE
  • RITONAVIR
  • COBICISTAT
  • RIFAMPICIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Limit alcohol consumption while on treatment with DEXAMETHASONE+OFLOXACIN.

    • Safety Warning

      Pregnancy

      caution

      There is limited data on how DEXAMETHASONE+OFLOXACIN affects pregnancy. Please consult your doctor if you are pregnant or planning pregnancy before using DEXAMETHASONE+OFLOXACIN.

    • Safety Warning

      Breast Feeding

      caution

      It is not known if DEXAMETHASONE+OFLOXACIN affects breastfeeding. Please consult your doctor before using DEXAMETHASONE+OFLOXACIN if you are a breastfeeding mother.

    • Safety Warning

      Driving

      caution

      DEXAMETHASONE+OFLOXACIN may cause side effects like temporary blurred vision, affecting your driving ability. Hence, do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before starting treatment with DEXAMETHASONE+OFLOXACIN.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases before starting the treatment with DEXAMETHASONE+OFLOXACIN.

    • Safety Warning

      Children

      caution

      DEXAMETHASONE+OFLOXACIN should be used for children only when recommended by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Know your allergy triggers, such as pollen, dust and other factors.
    • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
    • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before inserting and after removing the contact lens. 
    • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.
    • Avoid or limit the intake of alcohol and caffeine.

    Patients Concern

    Disease/Condition Glossary

    Bacterial eye infection: A bacterial eye infection occurs when bacteria invade any part of the eyeball or surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye inner eyelids). A bacterial eye infection symptoms include red eyes, pain, swelling of the eyes, watery eyes, itching, and blurry vision. Some very common eye infections are conjunctivitis (the inflammation and irritation of the eye's mucous membrane (conjunctiva), stye (bump on the eyelid), uveitis (inflammation of the uvea, middle layer of the eye), marginal keratitis (inflammation of the cornea), and blepharitis (inflammation of the eyelids).

    FAQs

    DEXAMETHASONE+OFLOXACIN contains Ofloxacin and Dexamethasone. It helps treat bacterial infections of the eye by preventing bacteria growth and reduces the redness and itchiness in the infected areas.

    It is advised to remove your contact lens if you are wearing it while administering eye drops. Also, remember to wash your hands before and after administering eye drops to avoid contamination.

    If you use other eye ointments/drops along with DEXAMETHASONE+OFLOXACIN, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.

    Do not stop using DEXAMETHASONE+OFLOXACIN even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.

    Take the missed dose of DEXAMETHASONE+OFLOXACIN as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

    Available Medicines for

    DEXAMETHASONE+OFLOXACIN

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