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  1. Home
  2. Medicine

  3. Divolin ER 250 mg Tablet 10's

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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
48 Hrs returnable
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Divolin ER 250 mg Tablet 10's, Pack of 10 TABLETS
rxMedicinePrescription drug

Whats That

tooltip

Composition :

VALPROIC ACID-250MG

Manufacturer/Marketer :

Talin Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

India

Manufacturer/Marketer address

4 - 5, Nagpal Market, Bazar Bhagtan Wala., ,Amritsar ,Punjab ,India Pin Code :143001
Other Info - DIV0114

Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Doctor image

Reviewed By

Sunny S

MBBS

Last Updated

Aug 20, 2024 | 12:54 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Divolin ER 250 mg Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Divolin ER 250 mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Divolin ER 250 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Divolin ER 250 mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Divolin ER 250 mg Tablet . Avoid getting pregnant while taking Divolin ER 250 mg Tablet as it could lead to serious birth defects. Do not stop taking Divolin ER 250 mg Tablet and consult your doctor immediately if you become pregnant.

Divolin ER 250 mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Do not consume alcohol while taking Divolin ER 250 mg Tablet as alcohol can worsen the side effects of the Divolin ER 250 mg Tablet , including sleepiness and dizziness.

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Pregnancy

Unsafe

Divolin ER 250 mg Tablet is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Divolin ER 250 mg Tablet .

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Breast Feeding

Caution

Divolin ER 250 mg Tablet passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Divolin ER 250 mg Tablet . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Caution

Divolin ER 250 mg Tablet may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Divolin ER 250 mg Tablet .

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Liver

Caution

Inform your doctor before receiving the Divolin ER 250 mg Tablet if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Divolin ER 250 mg Tablet .

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Consult your doctor

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

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Reference

  1. https://www.drugs.com/mtm/valproic-acid.html
  2. https://www.medicines.org.uk/emc/files/pil.6102.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/018081s065_018082s048lbl.pdf
  4. https://www.nhs.uk/medicines/valproic-acid/

About Divolin ER 250 mg Tablet

Divolin ER 250 mg Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Divolin ER 250 mg Tablet also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Divolin ER 250 mg Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Divolin ER 250 mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Divolin ER 250 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Divolin ER 250 mg Tablet should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Divolin ER 250 mg Tablet . If you are pregnant, do not take Divolin ER 250 mg Tablet because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Divolin ER 250 mg Tablet . If you are breastfeeding, inform your doctor before taking Divolin ER 250 mg Tablet . As Divolin ER 250 mg Tablet causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Divolin ER 250 mg Tablet as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Divolin ER 250 mg Tablet

Epilepsy (fits), Bipolar disorder, Migraine

Medicinal Benefits Mweb

Medicinal Benefits

Divolin ER 250 mg Tablet contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Divolin ER 250 mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Divolin ER 250 mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Side Effects of Divolin ER 250 mg Tablet

  • Stomach pain
  • Feeling or being sick
  • Diarrhoea
  • Dry or sore mouth or swollen gums
  • Shakes (tremors) in a part of your body
  • Unusual eye movements
  • Feeling tired or sleepy
  • Headache
  • Weight gain
  • Thinning hair, or changes to the colour or texture of your hair
  • Irregular or delayed periods

Drug Warnings

Before taking the Divolin ER 250 mg Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Divolin ER 250 mg Tablet . Consult your doctor immediately if you become pregnant while receiving a Divolin ER 250 mg Tablet . Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Divolin ER 250 mg Tablet .

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateLithium
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Divolin ER 250 mg Tablet:
Combining Sodium phenylbutyrate and Divolin ER 250 mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Divolin ER 250 mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Lithium with Divolin ER 250 mg Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Divolin ER 250 mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Vorinostat with Divolin ER 250 mg Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Divolin ER 250 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Ketamine and Divolin ER 250 mg Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Divolin ER 250 mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Leflunomide and Divolin ER 250 mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Divolin ER 250 mg Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Divolin ER 250 mg Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Divolin ER 250 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Using buprenorphine together with Divolin ER 250 mg Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Divolin ER 250 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
The combined use of Ertapenem and Divolin ER 250 mg Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Divolin ER 250 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Meropenam and Divolin ER 250 mg Tablet together can reduce the effect of Divolin ER 250 mg Tablet.

How to manage the interaction:
Co-administration of Meropenam and Divolin ER 250 mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Divolin ER 250 mg Tablet:
Co-administration of Teriflunomide and Divolin ER 250 mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Divolin ER 250 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • WARFARIN
  • ASPIRIN
  • CIMETIDINE
  • RITONAVIR
  • ERYTHROMYCIN
  • VENLAFAXINE
  • QUETIAPINE
  • CHOLESTYRAMINE
  • MEFLOQUINE
  • CHLOROQUINE

Habit Forming

No

Special Advise

  • Blood and urine tests may be affected by the Divolin ER 250 mg Tablet . Inform the person conducting the exams that you will be taking Divolin ER 250 mg Tablet .
  • If you are of childbearing age, utilise effective contraception continuously during your treatment with Divolin ER 250 mg Tablet .
  • Contact your doctor immediately if you become pregnant while taking Divolin ER 250 mg Tablet .

Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

Divolin ER 250 mg Tablet Substitute

Substitutes safety advice

  • Dicorate ER 250 Tablet 10's

    by Others

    ₹10.38per tablet

  • Dv Exel-250 Tablet 10's

    by Others

    ₹12.60per tablet

  • Divaprime OD 250 Tablet 10's

    by Others

    ₹8.46per tablet

  • Dvlyf XR 250 Tablet 10's

    by Others

    ₹8.28per tablet

  • Manigrain Er 250 Tablet 10's

    by Others

    ₹8.90per tablet
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