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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - DYF0005

Author Details

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About Dyfira 240 Capsule

Uses of Dyfira 240 Capsule

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Dyfira 240 Capsule

Drug Warnings

Drug-Drug Interactions

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Critical
Severe

Drug-Drug Interactions

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Critical
How does the drug interact with Dyfira 240 Capsule:
Co-administration of BCG vaccine with Dyfira 240 Capsule can increase the risk of infection.

How to manage the interaction:
Taking Dyfira 240 Capsule with the BCG vaccine can possibly lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Golimumab together with Dyfira 240 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Dyfira 240 Capsule and Golimumab, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a serious infection, sepsis, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without talking to a doctor.
Dimethyl fumarateCertolizumab
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Certolizumab and Dyfira 240 Capsule may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Dyfira 240 Capsule with Certolizumab can possibly result in an interaction, but it can be taken if a doctor has advised it. These signs may include a swollen spleen or liver, stomach pain, ongoing fever, night sweats, and weight loss. If you experience any of these symptoms, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Dyfira 240 Capsule with Natalizumab can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dyfira 240 Capsule with Natalizumab can possibly result in an interaction, but it can be taken if a doctor has advised it. It is important to be aware of any symptoms such as infections, neurological problems, fever, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, burning during urination, weakness, vision problems, or confusion. If you experience any of these symptoms, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Dyfira 240 Capsule with Voclosporin can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Dyfira 240 Capsule and Voclosporin, you can take these medicines together if prescribed by a doctor. Make sure to contact a doctor right away if you notice any signs of infection like fever, chills, or sore throat. Other symptoms to watch out for include diarrhea, muscle aches, difficulty breathing, weight loss, or pain while urinating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Teriflunomide and Dyfira 240 Capsule may significantly increase the risk of serious infections.

How to manage the interaction:
Although taking Dyfira 240 Capsule and Teriflunomide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - liver damage, complications, infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine or bleeding - please call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyfira 240 Capsule:
Taking Cladribine with Dyfira 240 Capsule can increase the risk of serious infections.

How to manage the interaction:
Taking Dyfira 240 Capsule with Cladribine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination, contact a doctor right away. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Mipomersen and Dyfira 240 Capsule may significantly increase the risk of liver problems.

How to manage the interaction:
Although taking Dyfira 240 Capsule and Mipomersen together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, liver damage, or bleeding - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Dyfira 240 Capsule with Fingolimod may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dyfira 240 Capsule can be taken with Fingolimod if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhea, sore throat, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Leflunomide with Dyfira 240 Capsule may increase the risk of serious infections. These medications may also lead to liver damage rarely.

How to manage the interaction:
Although there is a possible interaction, Dyfira 240 Capsule can be taken with Leflunomide if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhoea, sore throat, weight loss, red or inflamed skin, b1ody sores, pain or burning during urination. Seek immediate medical attention if you notice signs and symptoms of the liver such as fatigue, nausea, vomiting, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, and dark-coloured urine. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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DIMETHYL FUMARATE-240MGBacterial infection of unspecified site
Moderate
DIMETHYL FUMARATE-240MGOther diseases of liver
Moderate

Drug-Diseases Interactions

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DIMETHYL FUMARATE-240MGBacterial infection of unspecified site
Moderate
How does the disease interact with Dyfira 240 Capsule:
individuals should be monitored for herpes zoster signs and symptoms while taking Dyfira 240 Capsule because serious herpes zoster instances have been reported in individuals receiving the medication. Dyfira 240 Capsule has also been linked to other severe opportunistic infections, such as bacterial, fungal, and viral infections.

How to manage the interaction:
Patients should be monitored for signs/symptoms of herpes zoster (shingles) while on Dyfira 240 Capsule as serious cases of herpes zoster have occurred in patients treated with Dyfira 240 Capsule. Withholding Dyfira 240 Capsule treatment in patients with herpes zoster or other serious infections until the infection has resolved should be considered.
DIMETHYL FUMARATE-240MGOther diseases of liver
Moderate
How does the disease interact with Dyfira 240 Capsule:
Although there is no need to change the dosage when taking Dyfira 240 Capsule in patients with liver disease, caution is advised because these patients have not been examined with the drug. Patients using Dyfira 240 Capsule in post-marketing situations have experienced clinically severe liver damage. Serum aminotransferase rises to more than five times the upper limit of normal (ULN) and elevation of total bilirubin to more than two times the ULN have also been noted as signs or symptoms of liver impairment; both abnormalities disappeared after the medication was stopped.

How to manage the interaction:
Caution is recommended when using Dyfira 240 Capsule in patients with liver problems.
DIMETHYL FUMARATE-240MGOther disorders of white blood cells
Moderate
How does the disease interact with Dyfira 240 Capsule:
Dyfira 240 Capsule usage may result in lower lymphocyte numbers. It is recommended use with caution while deciding whether or not to restart Dyfira 240 Capsule therapy for these patients.

How to manage the interaction:
The use of Dyfira 240 Capsule may decrease white blood cell counts. Withholding treatment in patients with serious infections and interruption of therapy in patients with low white blood cell count should be considered.
DIMETHYL FUMARATE-240MGMultiple sclerosis
Moderate
How does the disease interact with Dyfira 240 Capsule:
Patients with multiple sclerosis (MS) who were taking Dyfira 240 Capsule experienced progressive multifocal leukoencephalopathy (PML). PML is an opportunistic viral infection of the brain brought on by the John Cunningham virus (JC virus), and it typically results in death or severe disability. For patients with MS, caution and monitoring are advised. When a patient exhibits the first PML symptom or sign, Dyfira 240 Capsule should be discontinued and a proper diagnostic examination should be carried out.

How to manage the interaction:
Dyfira 240 Capsule should be withheld at the first sign/symptom suggestive of Progressive multifocal leukoencephalopathy (PML-a viral infection) and an appropriate diagnostic evaluation should be performed.
DIMETHYL FUMARATE-240MGAcute renal failure
Moderate
How does the disease interact with Dyfira 240 Capsule:
Although there is no need to change the dosage for patients with renal failure, caution is advised when taking Dyfira 240 Capsule in these individuals because it has not been tested in this population.

How to manage the interaction:
Caution is recommended when using Dyfira 240 Capsule in patients with kidney impairment.

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