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  3. Eldepryl 10mg Tablet

Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

SELEGILINE-10MG

Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIPARKINSON AGENTS

Country of origin

India
Other Info - EL49997

Author Details

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FAQs

Eldepryl 10mg Tablet contains Selegiline, an antiparkinson agent that works by inhibiting the action of monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, improves the symptoms of Parkinson’s disease.

You recommend avoiding tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts as it may cause severe high blood pressure.

Eldepryl 10mg Tablet may cause low blood pressure in some patients, especially while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Hence, to avoid orthostatic hypotension, you are recommended to get up slowly after lying down or sitting.

Eldepryl 10mg Tablet is not recommended for glaucoma (damage of optic nerve that is essential for good vision) patients as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with Eldepryl 10mg Tablet.

You are recommended to avoid taking Eldepryl 10mg Tablet with escitalopram as it may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Eldepryl 10mg Tablet with other medicines.

No, Eldepryl 10mg Tablet does not cure Parkinson’s disease. Eldepryl 10mg Tablet is only used to reduce the symptoms of Parkinson’s disease.

Eldepryl 10mg Tablet should not be used with pain killers like meperidine, tramadol, methadone, propoxyphene and cough syrups containing dextromethorphan. Using together can cause severe side effects and can worsen your present condition.

Disclaimer

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Alcohol

Unsafe

Avoid consumption of alcohol with Eldepryl 10mg Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Eldepryl 10mg Tablet is a Category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant as Eldepryl 10mg Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Eldepryl 10mg Tablet is not recommended for breastfeeding mothers. However, please consult a doctor before taking Eldepryl 10mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Eldepryl 10mg Tablet may cause drowsiness or dizziness and make you fall asleep suddenly. It is an offence to drive if Eldepryl 10mg Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Eldepryl 10mg Tablet.

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Liver

Caution

Take Eldepryl 10mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Eldepryl 10mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Eldepryl 10mg Tablet is not recommended for children as the safety and efficacy were not established.

About Eldepryl 10mg Tablet

Eldepryl 10mg Tablet belongs to a class of antiparkinson drugs called monoamine oxidase-B inhibitors used in the treatment of Parkinson’s disease. Parkinson’s disease is a central nervous system disorder that affects movement. It causes stiffness, shaking, difficulty in walking, coordination and balance. In Parkinson’s patients, there is a decrease in dopamine (a chemical messenger that is important for movement control) levels as the nerve cells that produce dopamine begin to die.

Eldepryl 10mg Tablet contains Selegiline that works by inhibiting the action of an enzyme called monoamine oxidase-B that naturally breaks down dopamine. Thereby, increases the level of dopamine and restores its level in the brain thereby improving the symptoms of Parkinson’s disease.

Take Eldepryl 10mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take Eldepryl 10mg Tablet based on your medical condition. Some people may experience a sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. Most of these side effects of Eldepryl 10mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Eldepryl 10mg Tablet or any other medicines, please tell your doctor. Avoid taking Eldepryl 10mg Tablet if you are pregnant or breastfeeding and consult a doctor. Eldepryl 10mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Eldepryl 10mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Eldepryl 10mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, any unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Eldepryl 10mg Tablet.

Uses of Eldepryl 10mg Tablet

Parkinson’s disease

Medicinal Benefits Mweb

Medicinal Benefits

Eldepryl 10mg Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Eldepryl 10mg Tablet works by inhibiting the action of the monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, it improves the symptoms of Parkinson’s disease. Eldepryl 10mg Tablet can be used alone or in combination with other medicines such as levodopa to reduce uncontrolled movements.

Directions for Use

Take Eldepryl 10mg Tablet as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Side Effects of Eldepryl 10mg Tablet

  • Sore mouth
  • Swollen gums
  • Loss of balance
  • Difficulty in controlling movements
  • Headache
  • Dizziness
  • Nausea
  • Sleep disorders
  • Mouth ulcers
  • Constipation

Drug Warnings

If you are known to be allergic to Eldepryl 10mg Tablet or any other medicines, please tell your doctor. Avoid taking Eldepryl 10mg Tablet if you are pregnant or breastfeeding and consult a doctor. Eldepryl 10mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Eldepryl 10mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Eldepryl 10mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of the prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Eldepryl 10mg Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Eldepryl 10mg Tablet:
Co-administration of Amitriptyline together with Eldepryl 10mg Tablet can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Eldepryl 10mg Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Co-administration of Imipramine with Eldepryl 10mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Imipramine and Eldepryl 10mg Tablet together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Taking Eldepryl 10mg Tablet and Trazodone together can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Co-administration of Eldepryl 10mg Tablet with Trazodone can possibly result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Co-administration of Dextromethorphan and Eldepryl 10mg Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Eldepryl 10mg Tablet with Dextromethorphan can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Co-administration of Eldepryl 10mg Tablet with Rasagiline can increase the risk of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Eldepryl 10mg Tablet and Rasagiline, but can be taken together if prescribed by a doctor. However, if you experience confusion, hallucination (seeing or hearing things that do not exist), fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
SelegilinePhentermine
Critical
How does the drug interact with Eldepryl 10mg Tablet:
Co-administration of Phentermine with Eldepryl 10mg Tablet can increase blood pressure.

How to manage the interaction:
Taking Eldepryl 10mg Tablet with Phentermine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, or fainting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Co-administration of Eldepryl 10mg Tablet with Thiopental can reduce blood pressure.

How to manage the interaction:
Taking Eldepryl 10mg Tablet with Thiopental together can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any symptoms like lightheadedness, blurred vision, fainting or confusion, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Taking Eldepryl 10mg Tablet with Fluvoxamine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Fluvoxamine with Eldepryl 10mg Tablet can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience confusion, hallucination (seeing & hearing things that do not exist), seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor (shaking of hands & legs), incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Eldepryl 10mg Tablet:
Using pheniramine with selageline can cause severe high blood pressure

How to manage the interaction:
Taking Pheniramine with Eldepryl 10mg Tablet is not recommended, but it should be taken if prescribed by a doctor. However, if you experience headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Eldepryl 10mg Tablet:
When Paroxetine is taken with Eldepryl 10mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Paroxetine with Eldepryl 10mg Tablet can possibly lead to an interaction but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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SELEGILINE-10MGTyramine-containing food
Moderate

Drug-Food Interactions

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SELEGILINE-10MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Consuming Eldepryl 10mg Tablet with Tyramine-containing food it may increase the blood pressure. Avoid consuming Eldepryl 10mg Tablet with Tyramine-containing food.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RASAGILINE
  • LEVODOPA
  • DOPAMINE
  • AMANTADINE
  • ESCITALOPRAM
  • CITALOPRAM
  • FLUVOXAMINE
  • FLUOXETINE
  • SERTRALINE
  • PAROXETINE
  • PROTRIPTYLINE
  • AMITRIPTYLINE
  • VENLAFAXINE
  • DULOXETINE
  • PETHIDINE
  • TRAMADOL
  • CODEINE
  • MEPERIDINE
  • LINEZOLID
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • RIZATRIPTAN
  • DIGITALIS
  • CLONAZEPAM
  • IBUPROFEN
  • NARATRIPTAN
  • ALTRETAMINE

Habit Forming

No

Special Advise

  • Eldepryl 10mg Tablet may cause abnormalities in certain laboratory test results such as liver function tests and blood tests. Therefore, inform your doctor or lab technician that you are on treatment with Eldepryl 10mg Tablet before undergoing any tests.
  • Eldepryl 10mg Tablet should not be used at daily doses of more than 2.5 mg/day due to the risks associated with a change in the amount of chemical messenger in the brain called a neurotransmitter. 
  • Eldepryl 10mg Tablet is contraindicated for use with medicine containing meperidine, as serious reactions have been experienced in patients taking both medications together. 

Diet & Lifestyle Advise

  • Avoid intake of tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts.
  • Eat more fibre rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid consumption of alcohol as it may increase drowsiness.

Eldepryl 10mg Tablet Substitute

Substitutes safety advice

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