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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

SELEGILINE-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIPARKINSON AGENTS

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - SEL0040

Author Details

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FAQs

Selgin 10 mg Tablet contains Selegiline, an antiparkinson agent that works by inhibiting the action of monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, improves the symptoms of Parkinson’s disease.

You recommend avoiding tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts as it may cause severe high blood pressure.

Selgin 10 mg Tablet may cause low blood pressure in some patients, especially while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Hence, to avoid orthostatic hypotension, you are recommended to get up slowly after lying down or sitting.

Selgin 10 mg Tablet is not recommended for glaucoma (damage of optic nerve that is essential for good vision) patients as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with Selgin 10 mg Tablet .

You are recommended to avoid taking Selgin 10 mg Tablet with escitalopram as it may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Selgin 10 mg Tablet with other medicines.

No, Selgin 10 mg Tablet does not cure Parkinson’s disease. Selgin 10 mg Tablet is only used to reduce the symptoms of Parkinson’s disease.

Selgin 10 mg Tablet should not be used with pain killers like meperidine, tramadol, methadone, propoxyphene and cough syrups containing dextromethorphan. Using together can cause severe side effects and can worsen your present condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol with Selgin 10 mg Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Selgin 10 mg Tablet is a Category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant as Selgin 10 mg Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Selgin 10 mg Tablet is not recommended for breastfeeding mothers. However, please consult a doctor before taking Selgin 10 mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Selgin 10 mg Tablet may cause drowsiness or dizziness and make you fall asleep suddenly. It is an offence to drive if Selgin 10 mg Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Selgin 10 mg Tablet .

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Liver

Caution

Take Selgin 10 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Selgin 10 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Selgin 10 mg Tablet is not recommended for children as the safety and efficacy were not established.

About Selgin 10 mg Tablet

Selgin 10 mg Tablet belongs to a class of antiparkinson drugs called monoamine oxidase-B inhibitors used in the treatment of Parkinson’s disease. Parkinson’s disease is a central nervous system disorder that affects movement. It causes stiffness, shaking, difficulty in walking, coordination and balance. In Parkinson’s patients, there is a decrease in dopamine (a chemical messenger that is important for movement control) levels as the nerve cells that produce dopamine begin to die.

Selgin 10 mg Tablet contains Selegiline that works by inhibiting the action of an enzyme called monoamine oxidase-B that naturally breaks down dopamine. Thereby, increases the level of dopamine and restores its level in the brain thereby improving the symptoms of Parkinson’s disease.

Take Selgin 10 mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take Selgin 10 mg Tablet based on your medical condition. Some people may experience a sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. Most of these side effects of Selgin 10 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Selgin 10 mg Tablet or any other medicines, please tell your doctor. Avoid taking Selgin 10 mg Tablet if you are pregnant or breastfeeding and consult a doctor. Selgin 10 mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selgin 10 mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selgin 10 mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, any unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selgin 10 mg Tablet .

Uses of Selgin 10 mg Tablet

Parkinson’s disease

Medicinal Benefits Mweb

Medicinal Benefits

Selgin 10 mg Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Selgin 10 mg Tablet works by inhibiting the action of the monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, it improves the symptoms of Parkinson’s disease. Selgin 10 mg Tablet can be used alone or in combination with other medicines such as levodopa to reduce uncontrolled movements.

Directions for Use

Take Selgin 10 mg Tablet as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Side Effects of Selgin 10 mg Tablet

  • Sore mouth
  • Swollen gums
  • Loss of balance
  • Difficulty in controlling movements
  • Headache
  • Dizziness
  • Nausea
  • Sleep disorders
  • Mouth ulcers
  • Constipation

Drug Warnings

If you are known to be allergic to Selgin 10 mg Tablet or any other medicines, please tell your doctor. Avoid taking Selgin 10 mg Tablet if you are pregnant or breastfeeding and consult a doctor. Selgin 10 mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selgin 10 mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selgin 10 mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of the prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selgin 10 mg Tablet .

Drug-Drug Interactions

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SelegilineErgotamine
Critical

Drug-Drug Interactions

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SelegilineErgotamine
Critical
How does the drug interact with Selgin 10 mg Tablet:
When Ergotamine is taken with Selgin 10 mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Ergotamine and Selgin 10 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhea-call a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Tapentadol together with Selgin 10 mg Tablet can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Co-administration of Selgin 10 mg Tablet with Tapentadol is generally avoided as it can result in an interaction, but it can be taken if a doctor has advised it. If you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Nortriptyline with Selgin 10 mg Tablet might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Nortriptyline with Selgin 10 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Taking Selgin 10 mg Tablet with Fluvoxamine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Fluvoxamine with Selgin 10 mg Tablet can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience confusion, hallucination (seeing & hearing things that do not exist), seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor (shaking of hands & legs), incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Imipramine with Selgin 10 mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Imipramine and Selgin 10 mg Tablet together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Oxcarbazepine can increase the effects of Selgin 10 mg Tablet on serotonin levels (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin 10 mg Tablet with Oxcarbazepine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Selgin 10 mg Tablet with Rasagiline can increase the risk of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Selgin 10 mg Tablet and Rasagiline, but can be taken together if prescribed by a doctor. However, if you experience confusion, hallucination (seeing or hearing things that do not exist), fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
When Mephentermine is combined with Selgin 10 mg Tablet, may increase the risk of high blood pressure.

How to manage the interaction:
Mephentermine with Selgin 10 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Taking Selgin 10 mg Tablet and Trazodone together can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Co-administration of Selgin 10 mg Tablet with Trazodone can possibly result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Selgin 10 mg Tablet can increase the effects of Clomipramine on serotonin levels (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin 10 mg Tablet with Clomipramine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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SELEGILINE-10MGTyramine-containing food
Moderate

Drug-Food Interactions

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SELEGILINE-10MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Consuming Selgin 10 mg Tablet with Tyramine-containing food it may increase the blood pressure. Avoid consuming Selgin 10 mg Tablet with Tyramine-containing food.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RASAGILINE
  • LEVODOPA
  • DOPAMINE
  • AMANTADINE
  • ESCITALOPRAM
  • CITALOPRAM
  • FLUVOXAMINE
  • FLUOXETINE
  • SERTRALINE
  • PAROXETINE
  • PROTRIPTYLINE
  • AMITRIPTYLINE
  • VENLAFAXINE
  • DULOXETINE
  • PETHIDINE
  • TRAMADOL
  • CODEINE
  • MEPERIDINE
  • LINEZOLID
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • RIZATRIPTAN
  • DIGITALIS
  • CLONAZEPAM
  • IBUPROFEN
  • NARATRIPTAN
  • ALTRETAMINE

Habit Forming

No

Special Advise

  • Selgin 10 mg Tablet may cause abnormalities in certain laboratory test results such as liver function tests and blood tests. Therefore, inform your doctor or lab technician that you are on treatment with Selgin 10 mg Tablet before undergoing any tests.
  • Selgin 10 mg Tablet should not be used at daily doses of more than 2.5 mg/day due to the risks associated with a change in the amount of chemical messenger in the brain called a neurotransmitter. 
  • Selgin 10 mg Tablet is contraindicated for use with medicine containing meperidine, as serious reactions have been experienced in patients taking both medications together. 

Diet & Lifestyle Advise

  • Avoid intake of tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts.
  • Eat more fibre rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid consumption of alcohol as it may increase drowsiness.

Selgin 10 mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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