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  3. Gintrex 7.5mg Tablet

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

METHOTREXATE-7.5MG

Manufacturer/Marketer :

Roussel Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

IMMUNOSUPPRESSANTS

Manufacturer/Marketer address

Plot No:53,53/1384, Block B, 1st Floor, Bhagwan Tower, Laxmi Sagar, Bhubaneswar, District-Khorda, Odisha, Pin-751006
Other Info - GI47728

Author Details

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FAQs

Gintrex 7.5mg Tablet acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.

Gintrex 7.5mg Tablet works by suppressing the overactive immune system that is responsible for causing psoriasis. Gintrex 7.5mg Tablet interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis and psoriatic arthritis.

Diarrhoea might be a side-effect of Gintrex 7.5mg Tablet. Stop taking Gintrex 7.5mg Tablet and consult your doctor if you have diarrhoea. Do not take anti-diarrheal medicine on your own.

Gintrex 7.5mg Tablet can affect egg and sperm production and could lead to birth defects. Women of child-bearing potential and men using Gintrex 7.5mg Tablet must use effective contraception while on treatment with Gintrex 7.5mg Tablet and for at least six months after stopping the treatment. Gintrex 7.5mg Tablet can lead to infertility. Therefore male patients are advised to talk with their doctor regarding the possibility of sperm preservation before starting the treatment with Gintrex 7.5mg Tablet.

Gintrex 7.5mg Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Gintrex 7.5mg Tablet may cause mouth sores. Stop taking Gintrex 7.5mg Tablet and consult your doctor if you have sores in the mouth. Your doctor may recommend folate supplements to treat mouth sores.

Disclaimer

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Gintrex 7.5mg Tablet.

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Pregnancy

Unsafe

Gintrex 7.5mg Tablet may cause serious birth defects. It is not recommended to take Gintrex 7.5mg Tablet while you are pregnant.

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Breast Feeding

Unsafe

Gintrex 7.5mg Tablet passes into breast milk. Avoid breastfeeding whilst on treatment with Gintrex 7.5mg Tablet.

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Driving

Caution

Gintrex 7.5mg Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

Do not take Gintrex 7.5mg Tablet if you have chronic liver disease. Please consult your doctor if you have liver impairment before taking Gintrex 7.5mg Tablet.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Gintrex 7.5mg Tablet.

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Children

Caution

Gintrex 7.5mg Tablet should be used with caution in children and only if prescribed by the doctor.

About Gintrex 7.5mg Tablet

Gintrex 7.5mg Tablet belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis, severe psoriasis, and severe psoriatic arthritis. Gintrex 7.5mg Tablet is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).

Gintrex 7.5mg Tablet contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Gintrex 7.5mg Tablet prevents and stops the growth of cancer cells, thereby helps treat cancer. Gintrex 7.5mg Tablet treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.

In some cases, Gintrex 7.5mg Tablet may cause common side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience these side effects persistently.

Take Gintrex 7.5mg Tablet exactly as prescribed by the doctor; daily intake of Gintrex 7.5mg Tablet could lead to serious toxic effects. Do not take Gintrex 7.5mg Tablet if you are pregnant or breastfeeding. Gintrex 7.5mg Tablet may cause dizziness and fatigue, so drive only if you are alert. Avoid consuming alcohol whilst on treatment with Gintrex 7.5mg Tablet. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of Gintrex 7.5mg Tablet

Rheumatoid arthritis, Psoriatic arthritis, Psoriasis, Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Gintrex 7.5mg Tablet belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis (arthritis in children), severe psoriasis, and severe psoriatic arthritis. Gintrex 7.5mg Tablet helps treat rheumatoid arthritis and psoriatic arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Gintrex 7.5mg Tablet treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Gintrex 7.5mg Tablet is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). Gintrex 7.5mg Tablet prevents and stops the growth of cancer cells by interfering with DNA production. Gintrex 7.5mg Tablet may also be used to treat inflammatory bowel disease.

Directions for Use

Gintrex 7.5mg Tablet should be taken exactly as prescribed by the doctor. Tablet/capsule: Take it one hour after food in the evening or as advised by the doctor. Swallow the tablet/capsule as a whole with a glass of water whilst standing or sitting upright; do not break or chew it. Oral solution: Take the prescribed quantity by mouth using the dosing syringe.

Side Effects of Gintrex 7.5mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips

Drug Warnings

Do not take Gintrex 7.5mg Tablet if you are allergic to any of its contents; if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, chronic liver disease; if you are pregnant or breastfeeding. Talk to your doctor before taking Gintrex 7.5mg Tablet if you have/had liver or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any vaccinations, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Gintrex 7.5mg Tablet may cause dizziness and fatigue, so drive only if you are alert. Take Gintrex 7.5mg Tablet exactly as directed by the doctor as it may cause serious problems if not taken in the dose and duration prescribed by the doctor. Stop taking Gintrex 7.5mg Tablet and consult your doctor immediately if you have mouth sores, diarrhoea, a fever, dehydration, cough, bleeding, shortness of breath, any signs of infection, or a skin rash.

Drug-Drug Interactions

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MethotrexateEtretinate
Critical

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
How does the drug interact with Gintrex 7.5mg Tablet:
Co-administration of Etretinate with Gintrex 7.5mg Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Etretinate with Gintrex 7.5mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Taking tacrolimus with Gintrex 7.5mg Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between tacrolimus and Gintrex 7.5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting to a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Co-administration of Gintrex 7.5mg Tablet with Lansoprazole can increase the blood levels and side effects of Gintrex 7.5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Gintrex 7.5mg Tablet and Lansoprazole, you can take these medicines together if prescribed by a doctor. However, if you notice any symptoms of headaches, irritation, confusion, decreased hunger, fatigue, heart palpitations, or diarrhea, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Co-administration of Gintrex 7.5mg Tablet with cloxacillin can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between cloxacillin and Gintrex 7.5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, Consult a doctor. Do not stop using any medications without consulting to a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Coadministration of omeprazole with Gintrex 7.5mg Tablet may increase the levels and side effects of omeprazole.

How to manage the interaction:
Although there is a possible interaction between omeprazole and Gintrex 7.5mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
MethotrexatePhenylbutazone
Severe
How does the drug interact with Gintrex 7.5mg Tablet:
Coadministration of phenylbutazone with Gintrex 7.5mg Tablet may increase the levels and side effects of phenylbutazone.

How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Gintrex 7.5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Using thalidomide together with Gintrex 7.5mg Tablet can increase the risk of developing blood clots.

How to manage the interaction:
Although there is a possible interaction between thalidoamide and Gintrex 7.5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Co-administration of Gintrex 7.5mg Tablet and esomeprazole can increase the blood levels and side effects of Gintrex 7.5mg Tablet.

How to manage the interaction:
Although taking Esomeprazole with Gintrex 7.5mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Gintrex 7.5mg Tablet:
Co-administration of Gintrex 7.5mg Tablet with diclofenac can increase the levels and effects of Gintrex 7.5mg Tablet. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Gintrex 7.5mg Tablet and diclofenac, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Gintrex 7.5mg Tablet:
Coadministration of Gintrex 7.5mg Tablet with tolmetin can increase the levels and side effects of Gintrex 7.5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between tolmetin and Gintrex 7.5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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METHOTREXATE-7.5MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-7.5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of Gintrex 7.5mg Tablet. Avoid taking caffeine while taking Gintrex 7.5mg Tablet. This can increase the risk or severity of side effects.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CELECOXIB
  • ACETAMINOPHEN
  • HYDROCODONE
  • DULOXETINE
  • ETANERCEPT
  • ADALIMUMAB
  • ESOMEPRAZOLE
  • HYDROXYCHLOROQUINE

Habit Forming

No

Special Advise

  • Women of child-bearing age must use effective contraception whilst on treatment with Gintrex 7.5mg Tablet and for at least 6 months after the last dose.
  • Male patients are advised to consult their doctor regarding the possibility of sperm preservation before starting the treatment as Gintrex 7.5mg Tablet may cause infertility.
  • Gintrex 7.5mg Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
  • Your doctor may advise regular blood tests, kidney and liver tests to monitor your condition.
  • If you miss a dose of Gintrex 7.5mg Tablet, call your doctor and ask if you should take the missed dose or not.

Diet & Lifestyle Advise

Arthritis:

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Psoriasis:

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Cancer:

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

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