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  1. Home
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  3. Grinia Tablet 10's

Grinia Tablet 10's, Pack of 10 TABLETS
Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
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COD available

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Whats That

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Composition :

DOMPERIDONE-10MG + PARACETAMOL-500MG

Manufacturer/Marketer :

Pharmia Biogenesis Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Grinia Tablet

Grinia Tablet is a combination medicine used for the symptomatic treatment of migraine, and any medical condition with concomitant nausea/vomiting and fever/pain. Migraine is a neurological condition that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head, eyes, face, and neck. Symptoms may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Grinia Tablet is a combination of two drugs, namely: Domperidone and Paracetamol. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Grinia Tablet as prescribed. Your doctor will recommend how often you take Grinia Tablet based on your medical condition. Some people may experience some side effects, dry mouth, skin rash, anxiety, diarrhoea, and drowsiness. Most of these side effects of Grinia Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You can increase the efficacy of Grinia Tablet by taking a small meal or snacks frequently. Do not take Grinia Tablet if you are allergic to Grinia Tablet and other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Grinia Tablet . Inform your doctor if you have heart, kidney, and liver disease. Prolonged intake of Grinia Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Grinia Tablet , immediately contact your doctor.

Uses of Grinia Tablet

Migraine

Directions for Use

Tablet: Take it on empty stomach or as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Suspension: Shake the bottle well before use. Check the label for directions and take it with or without food in doses as prescribed by a doctor with the help of a measuring cup.

Medicinal Benefits

Grinia Tablet is a combination of two drugs namely; Domperidone and Paracetamol used to treat the vomiting and pain in people with migraines. Domperidone belongs to a class of prokinetic agents that prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting center (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Grinia Tablet together used to prevent nausea, vomiting, pain, and fever associated with migraine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Grinia Tablet if you are allergic to any of its contents or any other medicines, have a history of gastrointestinal bleeding, heart disease, liver/ kidney problem. Prolonged intake of Grinia Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). So, if you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Grinia Tablet , immediately contact your doctor. This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you are pregnant or breastfeeding, inform your doctor before using Grinia Tablet . Avoid consumption of alcohol while using Grinia Tablet as it may increase the side effects and make worse your condition. Grinia Tablet should not be given to children below five years of age. The use of Grinia Tablet is safe in children above five years of age if prescribed by the doctor. Do not exceed dose paracetamol more than 4 gm per day as it can damage your liver.

Drug-Drug Interactions

verifiedApollotooltip
DomperidoneClarithromycin
Severe
DomperidoneBepridil
Severe

Drug-Drug Interactions

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DomperidoneClarithromycin
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Grinia Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Grinia Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Grinia Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Grinia Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Cisapride can increase the blood levels of Grinia Tablet.

How to manage the interaction:
There may be a possibility of interaction between Grinia Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Nefazodone can increase the blood levels of Grinia Tablet.

How to manage the interaction:
There may be a possibility of interaction between Grinia Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Grinia Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Grinia Tablet:
Combining Mizolastine with Grinia Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Grinia Tablet and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Grinia Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Grinia Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Grinia Tablet:
Coadministration of Grinia Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Grinia Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favorite food at that particular time as your taste for that food may get turned off.
  • Include more cool beverages in your food like clear soup, flavored gelatin, carbonated beverages. Also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas and acidity.
  • Drink after or any other liquid at least 30 minutes after eating food. 
  • Avoid smoking and alcohol intake.
  • Avoid chronic stress as it can raise your migraine pain. Try to enjoy and spending time with your friends to cope with stress and practice mindfulness techniques.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Grinia Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:30 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Grinia Tablet is a combination of drugs namely; Domperidone and Paracetamol. Domperidone is a prokinetic that prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, used to prevent nausea, vomiting, pain, and fever associated with migraine.

Talk to your doctor if you do not feel better even after taking Grinia Tablet for 14 days. Do not take Grinia Tablet for longer durations unless prescribed by the doctor.

If you or someone else have taken too much of Grinia Tablet , contact your doctor or nearest hospital casualty department.

It is best to avoid alcohol while taking Grinia Tablet as it can make damage to your liver.

Yes, Grinia Tablet can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • SOTALOL
  • DILTIAZEM
  • VERAPAMIL
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • MOXIFLOXACIN
  • CISAPRIDE
  • DOLASETRON
  • WARFARIN
  • METOCLOPRAMIDE
  • CHOLESTYRAMINE

Special Advise

  • Prolonged intake of Grinia Tablet can increase the risk of cardiac arrhythmia (irregular heartbeat), so close monitoring of heartbeat is required.

Disease/Condition Glossary

Migraine: is a neurological condition that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head. People may experience migraine pain in the eyes face and neck. Symptoms may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound. Migraine attacks can last for hours to days, and the pain and symptoms can be so severe that it interferes with your daily activities.

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