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Alcohol
Caution
No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.
Pregnancy
Caution
Insusita-100 Tablet is not suggested during pregnancy since there is insufficient evidence on how it may impact a growing infant.
Breast Feeding
Unsafe
Consult your doctor; there is no substantial research yet on using Insusita-100 Tablet in breastfeeding/nursing mothers. Insusita-100 Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks.
Driving
Caution
Insusita-100 Tablet should not impair your ability to drive, or operate machinery or tools if your blood sugar levels are stable. When your blood sugar levels drop too low, your concentration suffers. If this occurs, refrain from driving or using equipment or tools until you feel better.
Liver
Caution
In rare cases, liver enzyme elevations have been reported in the prolonged usage of Insusita-100 Tablet . So, if you have or have a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.
Kidney
Unsafe
Acute renal failure has been reported in the patients taking Insusita-100 Tablet . In severe cases, it sometimes requires dialysis. Hence, dosage adjustment can be recommended in patients with moderate or severe kidney disease and patients with kidney failure (ESRD - end-stage renal dialysis).
Children
Unsafe
The safety and efficacy of Insusita-100 Tablet in children have not been established.
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About Insusita-100 Tablet
Insusita-100 Tablet belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in treating type 2 diabetes in adults. Insusita-100 Tablet is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.
Insusita-100 Tablet contains sitagliptin. Insusita-100 Tablet work by blocking the action of DPP-4 (an enzyme which destroys the hormone 'Incretin'). The enzyme 'Incretins' helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed.
Insusita-100 Tablet should be taken with food or an empty stomach. However, it should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Insusita-100 Tablet is hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of the nose and throat with common cold) and headache.
Insusita-100 Tablet should not be used in patients with type 1 diabetes and for treating diabetic ketoacidosis. Insusita-100 Tablet should not be stopped even if you feel better without consulting your doctor as the sugar levels change. If you stop taking Insusita-100 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Insusita-100 Tablet should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeed. Prolonged intake of Insusita-100 Tablet may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Insusita-100 Tablet is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Insusita-100 Tablet . Severe allergic reactions might occur in some patients taking Insusita-100 Tablet like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Insusita-100 Tablet in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Insusita-100 Tablet should be closely monitored as severe drug interaction has been observed.
Uses of Insusita-100 Tablet
Medicinal Benefits
Insusita-100 Tablet work by blocking the action of DPP-4 (an enzyme which destroys the hormone ‘Incretin’). The enzyme ‘Incretins’ helps produce more insulin only when required and reduces blood sugar produced by the liver when not needed. Thus, Insusita-100 Tablet plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
Directions for Use
Side Effects of Insusita-100 Tablet
Drug Warnings
Tell your doctor before consuming Insusita-100 Tablet if you have allergic reactions to sitagliptin, any medications, foods, or any components present in Insusita-100 Tablet . Prolonged intake of Insusita-100 Tablet may cause acute pancreatitis (swollen pancreas) and critical kidney problem. Increased risk of hypoglycaemia (low blood sugar level) can occur when Insusita-100 Tablet is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Insusita-100 Tablet . Severe allergic reactions might occur in some patients taking Insusita-100 Tablet like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions, including Stevens-Johnson syndrome. The safety and efficacy of Insusita-100 Tablet in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Insusita-100 Tablet should be closely monitored as severe drug interaction has been observed.
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