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  3. Ixapana 20Mg Capsule 6'S

Ixapana 20Mg Capsule 6'S, Pack of 6 CapsuleS
48 Hrs returnable
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Whats That

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Composition :

PANOBINOSTAT-20MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - IXA0003

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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FAQs

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Do not stop taking Ixapana 20Mg Capsule on your own. Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Do not hesitate to speak with your doctor if you experience difficulty taking Ixapana 20Mg Capsule.

No, it is unsafe to father a child while taking Ixapana 20Mg Capsule. It is recommended for sexually active men to use condoms while on treatment and for at least six months after their last dose of Ixapana 20Mg Capsule.

The amount of red blood cells, white blood cells, and platelets in your blood may decrease as a result of Ixapana 20Mg Capsule. This can lead to anaemia (shortness of breath, exhaustion, and weakness) and fatigue, and make you more prone to infection and increase your risk of bleeding. You will be given supportive medication to alleviate these adverse effects and increase your blood cell count if necessary.

Panobinostat can induce swelling in the hands, ankles, and feet (peripheral oedema). Fluid may also accumulate around the abdomen, making you feel bloated. Your doctor will discuss a treatment strategy for your fluid retention with you. Diuretics (water tablets) are typically used to assist your body in removing excess fluid.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Ixapana 20Mg Capsule.

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Pregnancy

Unsafe

Ixapana 20Mg Capsule should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy.

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Breast Feeding

Unsafe

You should not breastfeed when taking Ixapana 20Mg Capsule as it is unknown if the panobinostat can pass to your baby in the milk.

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Driving

Caution

Ixapana 20Mg Capsule can cause a drop in blood pressure, which can make you feel dizzy, lightheaded or like you are about to faint. If you feel dizzy or lightheaded when taking Ixapana 20Mg Capsule, you should not operate machinery or drive a car.

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Liver

Caution

Caution should be exercised. Monitor hepatic enzymes and adjust the dosage if abnormal liver function tests are observed during panobinostat therapy.

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Kidney

Caution

Limited information is available. Please inform your doctor before prescribing Ixapana 20Mg Capsule if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Ixapana 20Mg Capsule.

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Children

Consult your doctor

The safety and efficacy of Ixapana 20Mg Capsule in children has not been established.

Reference

  1. https://www.myeloma.org.uk/wp-content/uploads/2023/04/Myeloma-UK-Panobinostat-Treatment-Guide.pdf
  2. https://chemocare.com/druginfo/panobinostat
  3. https://www.clinicaltrialsarena.com/projects/farydak-panobinostat-treatment-multiple-myeloma/
  4. https://www.novartis.com/us-en/sites/novartis_us/files/farydak.pdf

About Ixapana 20Mg Capsule

Ixapana 20Mg Capsule belongs to the group of anti-cancer medicines used to treat multiple myeloma. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Sometimes, you may experience common side effects, such as diarrhoea, fatigue, nausea, peripheral oedema, decreased appetite, pyrexia, vomiting and hematologic laboratory abnormalities. Do not be reluctant to talk with your doctor if you persistently experience any of these side effects.

Do not take Ixapana 20Mg Capsule if you are allergic to any of its components or if you are pregnant. Do not try to become pregnant as Ixapana 20Mg Capsule may cause Embryo-Fetal Toxicity. Advise women not to breastfeed while taking Ixapana 20Mg Capsule. Inform your doctor if you are suffering from Hepatic dysfunction, as this increases panobinostat exposure. Your doctor reduces the dose in patients with mild to moderate hepatic (liver) impairment. It is recommended not to be used in people with severe hepatic (liver) impairment. If you feel dizzy or lightheaded when taking panobinostat, you should not operate machinery or drive a car.

Uses of Ixapana 20Mg Capsule

Multiple myeloma

Medicinal Benefits Mweb

Medicinal Benefits

Ixapana 20Mg Capsule contains Panobinostat, which belongs to the anti-cancer medicines used to treat multiple myeloma. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Side Effects of Ixapana 20Mg Capsule

  • Nausea
  • Vomiting
  • Appetite loss
  • Feel dizzy
  • Lightheaded
  • Low blood pressure
  • Diarrhea
  • Fatigue (tiredness)
  • Peripheral edema
  • Decreased appetite
  • Pyrexia
  • Vomiting
  • Hematologic laboratory abnormalities

Drug Warnings

Do not take Ixapana 20Mg Capsule if you are allergic to any of its contents. Inform your doctor about your health condition and medications to rule out any side effects/interactions. Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Ixapana 20Mg Capsule for as long as your doctor has prescribed. Do not stop Ixapana 20Mg Capsule midway. Talk to your doctor before taking Ixapana 20Mg Capsule if you have severe allergic reactions to Ixapana 20Mg Capsule or other medicines or suffer from any medical illness. Avoid taking Ixapana 20Mg Capsule if you are pregnant or breastfeeding because this Ixapana 20Mg Capsule can cause harmful effects on the unborn baby. Both women and men using this Ixapana 20Mg Capsule should use birth control to avoid pregnancy. Inform your doctor if you have a history of low blood pressure; your doctor will closely monitor and manage it. If you are taking medication to help lower your blood pressure, you may need to reduce or discontinue it while taking panobinostat.

Drug-Drug Interactions

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PanobinostatRifabutin
Critical
PanobinostatClofazimine
Severe

Drug-Drug Interactions

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PanobinostatRifabutin
Critical
How does the drug interact with Ixapana 20Mg Capsule:
Taking Rifabutin and Ixapana 20Mg Capsule may significantly reduce the blood levels of Ixapana 20Mg Capsule.

How to manage the interaction:
Taking Rifabutin with Ixapana 20Mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately, iff you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PanobinostatClofazimine
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Co-administration of Ixapana 20Mg Capsule with clofazimine can increase the risk of irregular heart rhythms. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhoea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ixapana 20Mg Capsule with clofazimine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
PanobinostatDiclofenac
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Diclofenac with Ixapana 20Mg Capsule can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Diclofenac and Ixapana 20Mg Capsule, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
PanobinostatAzithromycin
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Azithromycin with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of azithromycin alongside Ixapana 20Mg Capsule can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PanobinostatCladribine
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Combining Cladribine with Ixapana 20Mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Ixapana 20Mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PanobinostatPrasugrel
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Co-administration of Prasugrel with Ixapana 20Mg Capsule can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Prasugrel with Ixapana 20Mg Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PanobinostatBosutinib
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Bosutinib and Ixapana 20Mg Capsule can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between bosutinib and Ixapana 20Mg Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or fainting. Do not discontinue any medications without consulting a doctor.
PanobinostatBicalutamide
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Co-administration of Bicalutamide and Ixapana 20Mg Capsule together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Bicalutamide and Ixapana 20Mg Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PanobinostatKetoconazole
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Taking Ketoconazole and Ixapana 20Mg Capsule together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ketoconazole and Ixapana 20Mg Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PanobinostatDoxepin
Severe
How does the drug interact with Ixapana 20Mg Capsule:
Co-administration of Ixapana 20Mg Capsule with Doxepin can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ixapana 20Mg Capsule with Doxepin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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Habit Forming

No

Special Advise

  • Monitoring of complete blood count while taking Ixapana 20Mg Capsule is advised.
  • Drink plenty of fluids to prevent urinary problems.
  • If you are due to have any surgery, inform the doctor that you are taking Ixapana 20Mg Capsule.
  • Insomnia or difficulty sleeping at night is a common side effect of panobinostat. This may be minimised by taking panobinostat in the morning.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

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