apollo
0
  1. Home
  2. Medicine
  3. Mantedanib-100 Softgel Cap 10'S

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

NINTEDANIB-100MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase 3, New Delhi - 110020.
Other Info - MAN0479

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Mantedanib-100 Softgel Cap helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

Avoid smoking before starting the treatment while taking Mantedanib-100 Softgel Cap as smoking might alter the effectiveness of Mantedanib-100 Softgel Cap .

Mantedanib-100 Softgel Cap should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Mantedanib-100 Softgel Cap until your doctor asks you to stop it.

If you have any surgery, including dental surgery, please inform your doctor if you are taking Mantedanib-100 Softgel Cap as your doctor might stop Mantedanib-100 Softgel Cap before undergoing surgery.

In elderly patients, the risk of side effects is more if you are taking Mantedanib-100 Softgel Cap . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

Idiopathic pulmonary fibrosis is treated with Mantedanib-100 Softgel Cap (IPF; scarring of the lungs with an unknown cause). It's also used to treat fibrosing interstitial lung disorders.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Caution

It is not known if alcohol interacts with Mantedanib-100 Softgel Cap . However, as a precautionary measure, you are recommended not to consume alcohol with the Mantedanib-100 Softgel Cap to avoid unpleasant side effects.

bannner image

Pregnancy

Unsafe

Mantedanib-100 Softgel Cap is listed as pregnancy category D. Because Mantedanib-100 Softgel Cap can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Mantedanib-100 Softgel Cap .

bannner image

Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Mantedanib-100 Softgel Cap can be taken by breastfeeding mothers or not.

bannner image

Driving

Caution

Mantedanib-100 Softgel Cap may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

bannner image

Liver

Caution

Dose adjustment may be needed. Mantedanib-100 Softgel Cap is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

bannner image

Kidney

Caution

Dose adjustment may be needed. Mantedanib-100 Softgel Cap is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

bannner image

Children

Caution

Mantedanib-100 Softgel Cap is not recommended for children below 18 years as safety and effectiveness have not been established.

About Mantedanib-100 Softgel Cap

Mantedanib-100 Softgel Cap belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

Mantedanib-100 Softgel Cap contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Mantedanib-100 Softgel Cap helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Mantedanib-100 Softgel Cap if you are pregnant or breastfeeding. Mantedanib-100 Softgel Cap may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Mantedanib-100 Softgel Cap as it could lead to increased dizziness. Mantedanib-100 Softgel Cap is not recommended for children below 18 years as safety and effectiveness have not been established. Mantedanib-100 Softgel Cap is listed as pregnancy category D. Because Mantedanib-100 Softgel Cap can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Mantedanib-100 Softgel Cap . Consult your doctor if you are breastfeeding; your doctor will decide whether the Mantedanib-100 Softgel Cap can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Mantedanib-100 Softgel Cap

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

Mantedanib-100 Softgel Cap is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Mantedanib-100 Softgel Cap can help effectively slow the rate of lung function decline by 50%. Mantedanib-100 Softgel Cap helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Mantedanib-100 Softgel Cap helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Mantedanib-100 Softgel Cap

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

Drug Warnings

Do not use Mantedanib-100 Softgel Cap if you are allergic to any components present in Mantedanib-100 Softgel Cap . Mantedanib-100 Softgel Cap is listed as pregnancy category D; because Mantedanib-100 Softgel Cap can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Mantedanib-100 Softgel Cap . Consult your doctor if you are breastfeeding; your doctor will decide whether the Mantedanib-100 Softgel Cap can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Mantedanib-100 Softgel Cap may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Mantedanib-100 Softgel Cap as it could lead to increased dizziness. Mantedanib-100 Softgel Cap is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Teriflunomide and Mantedanib-100 Softgel Cap can increase the risk of liver problems.

How to manage the interaction:
Coadministration of Teriflunomide and Mantedanib-100 Softgel Cap can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately.
How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Mantedanib-100 Softgel Cap and primidone can reduce the blood levels of Mantedanib-100 Softgel Cap.

How to manage the interaction:
Although there is an interaction between Mantedanib-100 Softgel Cap and primidone, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Mantedanib-100 Softgel Cap with Rifampicin can decrease the blood levels of Mantedanib-100 Softgel Cap, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Mantedanib-100 Softgel Cap and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Dexamethasone may lower the blood levels of Mantedanib-100 Softgel Cap, making the medication less effective in treating your condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Mantedanib-100 Softgel Cap if prescribed by the doctor. Contact a doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mantedanib-100 Softgel Cap:
Taking Phenobarbital and Mantedanib-100 Softgel Cap can drastically lower Mantedanib-100 Softgel Cap levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Mantedanib-100 Softgel Cap can lead to interaction, they can be taken if recommended by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.
NintedanibFosphenytoin
Severe
How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Mantedanib-100 Softgel Cap with Fosphenytoin can reduce the levels of Mantedanib-100 Softgel Cap. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Mantedanib-100 Softgel Cap and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
NintedanibRifapentine
Severe
How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Mantedanib-100 Softgel Cap and Rifapentine can reduce the blood levels of Mantedanib-100 Softgel Cap.

How to manage the interaction:
There may be a possibility of interaction between Mantedanib-100 Softgel Cap and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibLomitapide
Severe
How does the drug interact with Mantedanib-100 Softgel Cap:
Co-administration of Lomitapide and Mantedanib-100 Softgel Cap can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Mantedanib-100 Softgel Cap can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Mantedanib-100 Softgel Cap:
Coadministration of Mantedanib-100 Softgel Cap with Carbamazepine can reduce the levels and effects of Mantedanib-100 Softgel Cap.

How to manage the interaction:
Although taking carbamazepine and Mantedanib-100 Softgel Cap together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Mantedanib-100 Softgel Cap:
Co-administration of Leflunomide and Mantedanib-100 Softgel Cap can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Mantedanib-100 Softgel Cap can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CYCLOSPORINE
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Special Advise

  • Regular blood tests and occasional tests of your bone marrow will be carried out to check whether the treatment is working. If it does work, it will usually be taken for life.

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Have a query?

Buy Now
Add to Cart