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  3. Nindev 100 mg Softgel Capsule 10's

Nindev 100 mg Softgel Capsule 10's, Pack of 10 CapsuleS
Nindev 100 mg Softgel Capsule 10's, Pack of 10 CapsuleS
Nindev 100 mg Softgel Capsule 10's, Pack of 10 CapsuleS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
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COD available

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Whats That

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Composition :

NINTEDANIB-100MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad ? 380015 Gujarat, India.
Other Info - NIN0046

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

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FAQs

NINDEV 100MG SOFTGEL CAPSULES helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.

Avoid smoking before starting the treatment while taking NINDEV 100MG SOFTGEL CAPSULES as smoking might alter the effectiveness of NINDEV 100MG SOFTGEL CAPSULES .

NINDEV 100MG SOFTGEL CAPSULES should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking NINDEV 100MG SOFTGEL CAPSULES until your doctor asks you to stop it.

If you have any surgery, including dental surgery, please inform your doctor if you are taking NINDEV 100MG SOFTGEL CAPSULES as your doctor might stop NINDEV 100MG SOFTGEL CAPSULES before undergoing surgery.

In elderly patients, the risk of side effects is more if you are taking NINDEV 100MG SOFTGEL CAPSULES . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

Idiopathic pulmonary fibrosis is treated with NINDEV 100MG SOFTGEL CAPSULES (IPF; scarring of the lungs with an unknown cause). It's also used to treat fibrosing interstitial lung disorders.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with NINDEV 100MG SOFTGEL CAPSULES . However, as a precautionary measure, you are recommended not to consume alcohol with the NINDEV 100MG SOFTGEL CAPSULES to avoid unpleasant side effects.

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Pregnancy

Unsafe

NINDEV 100MG SOFTGEL CAPSULES is listed as pregnancy category D. Because NINDEV 100MG SOFTGEL CAPSULES can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINDEV 100MG SOFTGEL CAPSULES .

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether NINDEV 100MG SOFTGEL CAPSULES can be taken by breastfeeding mothers or not.

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Driving

Caution

NINDEV 100MG SOFTGEL CAPSULES may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Caution

Dose adjustment may be needed. NINDEV 100MG SOFTGEL CAPSULES is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. NINDEV 100MG SOFTGEL CAPSULES is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Caution

NINDEV 100MG SOFTGEL CAPSULES is not recommended for children below 18 years as safety and effectiveness have not been established.

Product Substitutes

Reference

  1. https://www.nhs.uk/conditions/idiopathic-pulmonary-fibrosis/treatment/
  2. https://www.medicines.org.uk/emc/product/1786/smpc#gref
  3. https://www.medicines.org.uk/emc/files/pil.1786.pdf

About NINDEV 100MG SOFTGEL CAPSULES

NINDEV 100MG SOFTGEL CAPSULES belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

NINDEV 100MG SOFTGEL CAPSULES contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. NINDEV 100MG SOFTGEL CAPSULES helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking NINDEV 100MG SOFTGEL CAPSULES if you are pregnant or breastfeeding. NINDEV 100MG SOFTGEL CAPSULES may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with NINDEV 100MG SOFTGEL CAPSULES as it could lead to increased dizziness. NINDEV 100MG SOFTGEL CAPSULES is not recommended for children below 18 years as safety and effectiveness have not been established. NINDEV 100MG SOFTGEL CAPSULES is listed as pregnancy category D. Because NINDEV 100MG SOFTGEL CAPSULES can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINDEV 100MG SOFTGEL CAPSULES . Consult your doctor if you are breastfeeding; your doctor will decide whether the NINDEV 100MG SOFTGEL CAPSULES can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of NINDEV 100MG SOFTGEL CAPSULES

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

NINDEV 100MG SOFTGEL CAPSULES is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. NINDEV 100MG SOFTGEL CAPSULES can help effectively slow the rate of lung function decline by 50%. NINDEV 100MG SOFTGEL CAPSULES helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. NINDEV 100MG SOFTGEL CAPSULES helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of NINDEV 100MG SOFTGEL CAPSULES

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

Drug Warnings

Do not use NINDEV 100MG SOFTGEL CAPSULES if you are allergic to any components present in NINDEV 100MG SOFTGEL CAPSULES . NINDEV 100MG SOFTGEL CAPSULES is listed as pregnancy category D; because NINDEV 100MG SOFTGEL CAPSULES can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINDEV 100MG SOFTGEL CAPSULES . Consult your doctor if you are breastfeeding; your doctor will decide whether the NINDEV 100MG SOFTGEL CAPSULES can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. NINDEV 100MG SOFTGEL CAPSULES may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with NINDEV 100MG SOFTGEL CAPSULES as it could lead to increased dizziness. NINDEV 100MG SOFTGEL CAPSULES is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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NintedanibTeriflunomide
Severe
NintedanibPrimidone
Severe

Drug-Drug Interactions

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NintedanibTeriflunomide
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Teriflunomide and Nindev 100 mg Softgel Capsule can increase the risk of liver problems.

How to manage the interaction:
Coadministration of Teriflunomide and Nindev 100 mg Softgel Capsule can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately.
NintedanibPrimidone
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Nindev 100 mg Softgel Capsule and primidone can reduce the blood levels of Nindev 100 mg Softgel Capsule.

How to manage the interaction:
Although there is an interaction between Nindev 100 mg Softgel Capsule and primidone, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibRifampicin
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Nindev 100 mg Softgel Capsule with Rifampicin can decrease the blood levels of Nindev 100 mg Softgel Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Nindev 100 mg Softgel Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
NintedanibDexamethasone
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Dexamethasone may lower the blood levels of Nindev 100 mg Softgel Capsule, making the medication less effective in treating your condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Nindev 100 mg Softgel Capsule if prescribed by the doctor. Contact a doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
NintedanibPhenobarbital
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Taking Phenobarbital and Nindev 100 mg Softgel Capsule can drastically lower Nindev 100 mg Softgel Capsule levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Nindev 100 mg Softgel Capsule can lead to interaction, they can be taken if recommended by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.
NintedanibFosphenytoin
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Nindev 100 mg Softgel Capsule with Fosphenytoin can reduce the levels of Nindev 100 mg Softgel Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Nindev 100 mg Softgel Capsule and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
NintedanibRifapentine
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Nindev 100 mg Softgel Capsule and Rifapentine can reduce the blood levels of Nindev 100 mg Softgel Capsule.

How to manage the interaction:
There may be a possibility of interaction between Nindev 100 mg Softgel Capsule and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibLomitapide
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Co-administration of Lomitapide and Nindev 100 mg Softgel Capsule can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Nindev 100 mg Softgel Capsule can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NintedanibCarbamazepine
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Coadministration of Nindev 100 mg Softgel Capsule with Carbamazepine can reduce the levels and effects of Nindev 100 mg Softgel Capsule.

How to manage the interaction:
Although taking carbamazepine and Nindev 100 mg Softgel Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
NintedanibLeflunomide
Severe
How does the drug interact with Nindev 100 mg Softgel Capsule:
Co-administration of Leflunomide and Nindev 100 mg Softgel Capsule can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Nindev 100 mg Softgel Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CYCLOSPORINE
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Special Advise

  • Regular blood tests and occasional tests of your bone marrow will be carried out to check whether the treatment is working. If it does work, it will usually be taken for life.

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

NINDEV 100MG SOFTGEL CAPSULES Substitute

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