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Prescription drug
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

APREMILAST-30MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Return Policy :

Not Returnable

Therapeutic Class

[ANTIPSORIATICS]

Country of origin

INDIA

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103
Other Info - MPR0023

FAQs

Yes, Mprila Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Mprila Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.

Mprila Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.

Yes, Mprila Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Mprila Tablet . In case of big weight loss, inform your doctor. Your doctor may consider stopping Mprila Tablet .

Rifampicin is an antibiotic. You should not take rifampicin if you are taking Mprila Tablet . Rifampicin interferes with the working of Mprila Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Mprila Tablet .

As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

No reported interaction. But, it is best to avoid alcohol while taking medication.

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Pregnancy

Consult your doctor

There are no competent and well-controlled studies in pregnant women. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor; there has been no significant research on the use of Candid Cream 30 gm in breastfeeding/nursing mothers. If Candid Cream 30 gm is applied to the breast or nipple, wash the area properly before nursing the child.

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Driving

Safe if prescribed

Candid Cream 30 gm has no or negligible impact on the ability to drive or operate machinery.

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Liver

Consult your doctor

Limited information is available; hence, if you have any concerns, discuss them with your doctor.

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Kidney

Consult your doctor

Limited information is available; hence, if you have any concerns, discuss them with your doctor.

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Children

Safe if prescribed

Candid Cream 30 gm can be used safely for children provided a child specialist has prescribed the dose.

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Heart

Candid Cream 30 gm can be used safely due to minimal systemic absorption. If you have any concerns, please discuss them with your doctor.

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Geriatrics

Consult your doctor

Limited information available about the use of Candid Cream 30 gm in geriatric patients. Please consult your physician.

About Mprila Tablet

Mprila Tablet belongs to a class of drugs known as phosphodiesterase 4 (PDE4) inhibitors. It is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Mprila Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Mprila Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin), and thus, lowers the signs and symptoms of these conditions.

Take Mprila Tablet as prescribed by your doctor. You are advised to take Mprila Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Mprila Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Mprila Tablet should not be taken in the conditions like depression as it is getting worse with thoughts of suicide. Before starting Mprila Tablet , please inform your doctor if you have any allergy to Mprila Tablet and its part. Mprila Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Mprila Tablet . Mprila Tablet does not affect the ability to drive and use machines.

Uses of Mprila Tablet

Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Medicinal Benefits Mweb

Medicinal Benefits

Mprila Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Mprila Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

Directions for Use

Take Mprila Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Mprila Tablet with or without food. Swallow the Mprila Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Side Effects of Mprila Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

Drug Warnings

Inform your doctor before using Mprila Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Mprila Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Mprila Tablet if you have severe kidney problems. Inform your doctor while taking Mprila Tablet if you lose weight without meaning to. Mprila Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Mprila Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Mprila Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Mprila Tablet .

Drug-Drug Interactions

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ApremilastRifapentine
Severe

Drug-Drug Interactions

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How does the drug interact with Mprila Tablet:
Coadministration of phenobarbital with Mprila Tablet can drastically lower Mprila Tablet levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking phenobarbital with Mprila Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Mprila Tablet:
Rifapentine may decrease the blood levels of Mprila Tablet, which may make Mprila Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Mprila Tablet and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mprila Tablet:
Coadministration of Phenytoin with Mprila Tablet may reduce the blood levels of Mprila Tablet, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Mprila Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Mprila Tablet:
Taking Mprila Tablet with rifampicin can decrease the blood levels of Mprila Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Mprila Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mprila Tablet:
Coadministration of Nevirapine with Mprila Tablet may decrease the blood levels of Mprila Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Mprila Tablet and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastEnzalutamide
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Enzalutamide with Mprila Tablet may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Mprila Tablet and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastMitotane
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Mitotane with Mprila Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Mprila Tablet and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mprila Tablet:
Taking Mprila Tablet with carbamazepine can significantly reduce the blood levels of Mprila Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Mprila Tablet with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ApremilastFosphenytoin
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Fosphenytoin with Mprila Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Mprila Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mprila Tablet:
Coadministration of Mprila Tablet with primidone may decrease the blood levels of Mprila Tablet, which may make Mprila Tablet less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Mprila Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Special Advise

  • Mprila Tablet is a well-tolerated medicine. Mild stomach upset may arise early during the treatment.
  • Monitor your weight repeatedly as Mprila Tablet may lead to weight loss.
  • Inform your doctor immediately if you experience new or worsened depression, suicidal thoughts, unexplained weight loss, or other mood changes.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

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