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  1. Home
  2. Medicine

  3. Obparp-150 Tablet 8's

Obparp-150 Tablet 8's, Pack of 8 TabletS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
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Whats That

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Composition :

OLAPARIB-150MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - OBP0009

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Obparp-150 Tablet 8's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

If you are allergic to Olaparib or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Obparp-150 Tablet 8's.

Yes, Obparp-150 Tablet 8's can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Yes, Olaparib was generally a well-tolerated medication. Take Obparp-150 Tablet 8's pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Obparp-150 Tablet 8's unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Obparp-150 Tablet 8's therapy or adjust your Obparp-150 Tablet 8's dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Obparp-150 Tablet 8's.

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Pregnancy

Unsafe

Obparp-150 Tablet 8's should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Obparp-150 Tablet 8's and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Unsafe

Do not breastfeed during this treatment because the medicine may pass into your milk. Doctors normally advise against breastfeeding throughout this treatment and for one month after the final medication is taken.

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Driving

Caution

Obparp-150 Tablet 8's may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Caution

The safety and effectiveness of Obparp-150 Tablet 8's in pediatric patients have not been established.

Product Substitutes

Reference

  1. https://www.myeloma.org.uk/wp-content/uploads/2023/04/Myeloma-UK-Panobinostat-Treatment-Guide.pdf
  2. https://www.lynparza.com/
  3. https://medlineplus.gov/druginfo/meds/a614060.html#:~:text=Olaparib%20is%20used%20alone%20or,tissue%20that%20lines%20the%20abdomen)
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208558s001lbl.pdf
  5. https://www.medicines.org.uk/emc/product/9204/pil#gref
  6. https://reference.medscape.com/drug/lynparza-olaparib-999934
  7. https://www.medicines.org.uk/emc/files/pil.9204.pdf
  8. https://www.lynparzahcp.com/
  9. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/olaparib-lynparza#:~:text=Olaparib%20stops%20PARP%20working.&text=healthy.,damage%2C%20the%20cancer%20cells%20die.
  10. https://www.lynparza.com/what-is-lynparza.html
  11. https://www.drugs.com/drug-interactions/olaparib-index.html?filter=3

About Obparp-150 Tablet 8's

Obparp-150 Tablet 8's belongs to a group of medicines known as 'anti-cancer' drugs used to treat various cancers, including Ovarian, breast, pancreatic, and prostate. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs.

Obparp-150 Tablet 8's contains Olaparib, a targeted drug called a PARP inhibitor. PARP (polyadenosine 5’-diphosphoribose polymerase) is a protein that helps damaged cells repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage.

Use this medicine as directed by your doctor. You may sometimes experience shortness of breath (dyspnoea), feeling very tired, pale skin or fast heartbeat, anaemia, feeling sick (nausea), being sick (vomiting), indigestion or heartburn (dyspepsia), loss of appetite, headache, changes in taste of foods (dysgeusia), feeling dizzy, cough and diarrhoea. Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

To treat your condition effectually, continue taking Obparp-150 Tablet 8's for as long as your doctor has prescribed. Do not stop using the Obparp-150 Tablet 8's midway. Talk to your doctor before taking Obparp-150 Tablet 8's if you have severe allergic reactions to Obparp-150 Tablet 8's or other medicines or suffer from severe infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Obparp-150 Tablet 8's if you are pregnant or breastfeeding because this Obparp-150 Tablet 8's can cause harmful effects on the unborn baby. Both women and men using this Obparp-150 Tablet 8's should use birth control to avoid pregnancy. While on Obparp-150 Tablet 8's treatment, you should avoid eating grapefruit, Seville oranges or consuming grapefruit juice since it can affect how the medicine works.

Uses of Obparp-150 Tablet 8's

Cancer (Ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer)

Medicinal Benefits Mweb

Medicinal Benefits

Obparp-150 Tablet 8's contains Olaparib, a targeted drug called a PARP inhibitor. PARP is a protein that helps damaged cells to repair themselves. Olaparib stops PARP working. Some cancer cells rely on PARP to keep their DNA healthy. So, the cancer cells die when Olaparib stops PARP from repairing DNA damage. Thus, it treats various cancers, including Ovarian, breast, pancreatic, and prostate. It can be used alone or with other chemotherapy drugs, depending on your type of cancer.

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Side Effects of Obparp-150 Tablet 8's

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Feeling tired or weak (fatigue)
  • Feeling very tired
  • Indigestion or heartburn (dyspepsia)
  • Loss of appetite
  • Headache
  • Changes in the taste of foods (dysgeusia)
  • Feeling dizzy
  • Cough
  • Shortness of breath (dyspnoea)
  • Diarrhoea
  • Low white blood cell count (leukopenia or neutropenia)
  • Rash
  • Sore mouth (stomatitis)
  • Upper abdominal pain (pain in the stomach area under the ribs)
  • Blood clot in a deep vein, usually in the leg (venous thrombosis)

Drug Warnings

Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Obparp-150 Tablet 8's for as long as your doctor has prescribed. Do not stop Obparp-150 Tablet 8's midway. Talk to your doctor before taking Obparp-150 Tablet 8's if you have severe allergic reactions to Obparp-150 Tablet 8's or other medicines or suffer from any medical illness. Avoid taking Obparp-150 Tablet 8's if you are pregnant or breastfeeding because this Obparp-150 Tablet 8's can cause harmful effects on the unborn baby. Both women and men using this Obparp-150 Tablet 8's should use birth control to avoid pregnancy. Do not start Obparp-150 Tablet 8's unless patients have recovered from haematological damage induced by previous chemotherapy (Grade 1). Check full blood count for cytopenia at baseline and monthly afterwards for clinically significant changes during treatment. For persistent haematological toxicity, discontinue Obparp-150 Tablet 8's and monitor blood count weekly until recovery. Do not receive any immunization or vaccination without your doctor's approval while taking the Obparp-150 Tablet 8's.

Drug-Drug Interactions

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OlaparibDexamethasone
Severe
OlaparibVoriconazole
Severe

Drug-Drug Interactions

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OlaparibDexamethasone
Severe
How does the drug interact with Obparp-150 Tablet:
Co-administration of Dexamethasone together with Obparp-150 Tablet can reduce the blood levels of Obparp-150 Tablet.

How to manage the interaction:
Although taking Obparp-150 Tablet and Dexamethasone together can evidently cause an interaction, it can be taken if a doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
OlaparibVoriconazole
Severe
How does the drug interact with Obparp-150 Tablet:
When Obparp-150 Tablet is taken with Voriconazole may significantly increase the blood levels of Obparp-150 Tablet which increases risk of side effects.

How to manage the interaction:
Although taking Voriconazole and Obparp-150 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
OlaparibTeriflunomide
Severe
How does the drug interact with Obparp-150 Tablet:
Using Teriflunomide together with Obparp-150 Tablet may increase the risk of infections.

How to manage the interaction:
Combining Teriflunomide and Obparp-150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibEnzalutamide
Severe
How does the drug interact with Obparp-150 Tablet:
Co-administration of Enzalutamide and Obparp-150 Tablet may decrease the blood levels of Obparp-150 Tablet, which may make Obparp-150 Tablet less effective in treating your condition.

How to manage the interaction:
Although taking Enzalutamide and Obparp-150 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
OlaparibCladribine
Severe
How does the drug interact with Obparp-150 Tablet:
Combining Cladribine with Obparp-150 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Obparp-150 Tablet with Cladribine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
OlaparibBoceprevir
Severe
How does the drug interact with Obparp-150 Tablet:
Using Boceprevir and Obparp-150 Tablet can increase the blood levels of Obparp-150 Tablet.This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Boceprevir and Obparp-150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibRifampicin
Severe
How does the drug interact with Obparp-150 Tablet:
Taking Obparp-150 Tablet with rifampicin can decrease the blood levels of Obparp-150 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Obparp-150 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
OlaparibIndinavir
Severe
How does the drug interact with Obparp-150 Tablet:
Using Indinavir and Obparp-150 Tablet can increase the blood levels of Obparp-150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Indinavir and Obparp-150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
OlaparibPosaconazole
Severe
How does the drug interact with Obparp-150 Tablet:
Using Posaconazole and Obparp-150 Tablet can increase the blood levels of Obparp-150 Tablet. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort.

How to manage the interaction:
Although there is an interaction between posaconazole and Obparp-150 Tablet, it can be taken if advised by a doctor. However, if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without first consulting a doctor.
OlaparibAdalimumab
Severe
How does the drug interact with Obparp-150 Tablet:
Using adalimumab together with Obparp-150 Tablet may increase the risk of infections.

How to manage the interaction:
Combining adalimumab and Obparp-150 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • DARUNAVIR
  • APREPITANT
  • BCG VACCINE
  • DENGUE VACCINE
  • MUMPS (LIVE ATTENUATED)
  • CIPROFLOXACIN
  • FLUCONAZOLE
  • ITRACONAZOLE

Habit Forming

No

Special Advise

  • Pregnancy testing is recommended for females of reproductive potential prior to initiating treatment with Obparp-150 Tablet 8's.
  • Obparp-150 Tablet 8's should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Obparp-150 Tablet 8's.
  • Monitor complete blood count for cytopenia at baseline and monthly for clinically significant changes during treatment.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Peripheral blood counts should be frequently monitored during Obparp-150 Tablet 8's treatment and, when appropriate, until recovery is achieved.
  • Do not donate sperm during treatment with Obparp-150 Tablet 8's for three months after your last dose.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Obparp-150 Tablet 8's Substitute

Substitutes safety advice

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