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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

ACICLOVIR-5%W/W

Manufacturer/Marketer :

FDC Ltd

Consume Type :

Topical

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - OCU0090

Author Details

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About Ocuvir 5% Skin Cream

Uses of Ocuvir 5% Skin Cream

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Ocuvir 5% Skin Cream

Drug Warnings

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Drug-Diseases Interactions

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ACICLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
ACICLOVIR-5%W/WVolume depletion
Moderate

Drug-Diseases Interactions

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ACICLOVIR-5%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Ocuvir 5% Skin Cream 10 gm:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.

How to manage the interaction:
The use of Ocuvir 5% Skin Cream 10 gm in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACICLOVIR-5%W/WVolume depletion
Moderate
How does the disease interact with Ocuvir 5% Skin Cream 10 gm:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.

How to manage the interaction:
Ocuvir 5% Skin Cream 10 gm is excreted through the kidneys, dehydration may cause damage to kidney functions. Ocuvir 5% Skin Cream 10 gm infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACICLOVIR-5%W/WCare involving dialysis
Moderate
How does the disease interact with Ocuvir 5% Skin Cream 10 gm:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.

How to manage the interaction:
Patients undergoing hemodialysis should be given Ocuvir 5% Skin Cream 10 gm after completing hemodialysis as hemodialysis removes 60% of Ocuvir 5% Skin Cream 10 gm from the body.

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